First published in 1905, the "Journal of the American Medical Association" (JAMA) is the leading medical journal in the United States. This edition includes issues 1-9 of volume 45, featuring groundbreaking research studies, insightful commentaries, and thought-provoking editorials on a wide range of topics. With contributions from leading researchers and clinicians from around the world, this journal is an essential resource for anyone interested in staying up to date on the latest developments in the field of medicine. This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.