This is an open access book. It has been two years since the COVID-19 pandemic swept across the world. This has more or less left a mark of memories and trauma for more or fewer people. This pandemic reminds people around the world that there are things that can happen without people knowing it. People start to worry and pessimistically see the uncertainty that lies in the future. To deal with this, a strategy is needed through educational innovation and social science to answer and face the challenges of uncertainty in the future. Breakthroughs in education and social science are the most strategic ways to build and enhance human capacity to solve problems, environmental and social problems. The spirit of innovation, rising from an economic downturn, the use of technology is obtained through the role of educational institutions. This can be interpreted that innovation in education and social science produces superior humans, who have good behavior, and wise humans. So that in the face of uncertainty in the post-pandemic period, humans have strategies and become more prepared. To find out more about strategies for dealing with and responding to future uncertainties after the pandemic through educational innovations and social science, it is necessary to conduct research or studies that discuss these matters and be published widely. To support this, Universitas PGRI Yogyakarta held an international conference and Call for Papers The 1st UPY International Conference on Education and Social Science (UPINCESS) “Strategies to Deal with Uncertainty through Education and Social Science Innovation” on June 15, 2022.