Dermatology Made Easy

Dermatology Made Easy
Author: Amanda Oakley
Publisher: Scion Publishing Ltd
Total Pages: 438
Release: 2017-05-06
Genre: Medical
ISBN: 1911510118

A concise overview of the common dermatological conditions most likely to present in general medicine From reviews: "... a perfect solution to the constant struggle that dermatology diagnosis presents to primary care physicians and other providers... This well-formatted book covers a vast array of topics ranging from common to rare skin disorders. The pictures are immensely helpful in the understanding of various skin rashes...." Fam Med 2019;51(5):451–452. “... easy to read and informative. One cannot emphasise enough the quality and comprehensive nature of the photographic content.... As someone who was interested in dermatology even as a medical student my only regret is that this book was not around when I was a student as it would have very adequately guided me into my beloved subspecialty.” Ulster Med J 2017;86(3):1–1. “The introduction outlines dermatological conditions by symptom, morphology and body site, providing an excellent index prior to delving into greater detail in the following chapters. The logical approach and level of detail make this text perfect for medical students, interns/residents, primary care physicians and other specialists who wish to quickly identify differential diagnoses or refresh their knowledge of dermatological conditions.” A Lecturer in Dermatology Dermatology Made Easy is based on the hugely popular DermNet New Zealand website and is designed to help GPs, medical students and dermatologists diagnose skin conditions with confidence. The book starts by providing a series of comprehensive tables, complete with over 500 thumbnail photos, to aid diagnosis according to symptoms, morphology, or body site. Once you have narrowed down the diagnosis, cross-references then guide you to more detailed descriptions, and another 700 photographs, covering: common infections inflammatory rashes non-inflammatory conditions skin lesions Every section provides consistent information on the disorder: who gets it and what causes it? what are the clinical features and does it cause any complications? how do you diagnose it? how do you treat it and how long does it take to resolve? The book concludes with a comprehensive section on further investigations and treatment options. Dermatology Made Easy combines the essential focus of the Made Easy book series with the authority and knowledge base of DermNet New Zealand’s unparalleled resources. Printed in full colour throughout.

Retinoids in Dermatology

Retinoids in Dermatology
Author: Ayse Serap Karadag
Publisher: CRC Press
Total Pages: 508
Release: 2019-10-28
Genre: Medical
ISBN: 0429852614

Retinoids are valuable drugs in the dermatologic armamentarium, being employed in daily clinical practice. The text provides an in-depth update on the latest thinking on pharmacology, clinical use, side effects, and follow-up of retinoid therapy in dermatology; it also addresses topics related to retinoid use in special circumstances, such as vulnerable populations, concomitant surgery, and aesthetic procedures. CONTENTS: The background of retinoids * Mechanism of action of vitamin A * Mechanism of action of topical retinoids * Mechanism of action of isotretinoin * Mechanism of action of acitretin * Mechanism of action of bexarotene * Mechanism of action of alitretinoin * Effects of retinoids at the cellular level (differentiation, apoptosis, autophagy, cell cycle regulation, and senescence) * Effects of retinoids at the systemic level * New aspects of isotretinoin teratogenicity * Mucocutaneous side effects * Ophthalmologic side effects * Musculoskeletal side effects * Neurologic side effects * Psychiatric side effects * Gastrointestinal side effects * Endocrine and metabolic side effecs * Other systemic side effects: Cardiovascular, pulmonary, otolaryngorhinologic, genitourinary, renal, and immunologic * Retinoids in acne * Retinoids in hidradenitis suppurativa/acne inversa * Retinoids in rosacea * Retinoids in hair disorders * Retinoids in psoriasis * Retinoids in keratinization disorders * Retinoids in antiaging therapy * Retinoids in other skin diseases * Retinoids in lymphoma * Retinoids in cutaneous chemoprophylaxis * Guide to good clinical practice for vulnerable populations (infancy, childhood, fertile period, elderly) * Retinoids and concomitant surgery * Retinoids and concomitant aesthetic procedures * Laboratory and clinical follow-up * Teratogenicity and registry programs * Management of vitamin A and retinoid side effects * Future and novel unexplored indications of retinoids Published in association with the Journal of Dermatological Treatment.

Hepatotoxicity

Hepatotoxicity
Author: Hyman J. Zimmerman
Publisher: Lippincott Williams & Wilkins
Total Pages: 848
Release: 1999
Genre: Medical
ISBN: 9780781719520

Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

Advances in Acne Management, An Issue of Dermatologic Clinics, E-Book

Advances in Acne Management, An Issue of Dermatologic Clinics, E-Book
Author: James Q. Del Rosso
Publisher: Elsevier Health Sciences
Total Pages: 233
Release: 2016-04-20
Genre: Medical
ISBN: 0323417531

This most common of all dermatologic conditions seen by dermatologists. What are new developments. What do dermatologists need to best treat their patients? In this issue of Dermatologic Clinics, expert practitioners and academics, Dr. James Del Rosso and Dr. Joshua Zeichner lead distinguished clinicians in presenting such topics as: How the Internet and Social Media Have Changed the Management of Acne; Evaluation of Acne Scars: How to Assess Them and What To Tell The Patient; Pathophysiology of Acne; The Role of Skin Care in the Management of Acne Vulgaris; Top Ten List of Clinical Pearls in the Treatment of Acne Vulgaris; Use of Oral Contraceptives for Acne Vulgaris: Practical Considerations in Real World Practice; Use of Antibiotics in Acne: Achieving Optimal Outcomes While Maintaining Antibiotic Stewardship; Status Report on Oral Isotretinoin: Has Anything Changed That Is Relevant to Clinicians?; Safety Considerations and Monitoring in Patients Treated with Systemic Medications for Acne; Evaluation and Management of Refractory Acne Vulgaris in Adolescent and Adult Men; Physical Modalities in the Management of Acne; 12. Cases of "Acne" That Turned Out To Not Be Acne.

Drug-Induced Liver Injury

Drug-Induced Liver Injury
Author:
Publisher: Academic Press
Total Pages: 290
Release: 2019-07-13
Genre: Medical
ISBN: 0128173173

Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series

Pharmaceutical and Medical Device Safety

Pharmaceutical and Medical Device Safety
Author: Sonia Macleod
Publisher: Bloomsbury Publishing
Total Pages: 321
Release: 2019-02-21
Genre: Law
ISBN: 1509916725

This book examines how regulatory and liability mechanisms have impacted upon product safety decisions in the pharmaceutical and medical devices sectors in Europe, the USA and beyond since the 1950s. Thirty-five case studies illustrate the interplay between the regulatory regimes and litigation. Observations from medical practice have been the overwhelming means of identifying post-marketing safety issues. Drug and device safety decisions have increasingly been taken by public regulators and companies within the framework of the comprehensive regulatory structure that has developed since the 1960s. In general, product liability cases have not identified or defined safety issues, and function merely as compensation mechanisms. This is unsurprising as the thresholds for these two systems differ considerably; regulatory action can be triggered by the possibility that a product might be harmful, whereas establishing liability in litigation requires proving that the product was actually harmful. As litigation normally post-dates regulatory implementation, the 'private enforcement' of public law has generally not occurred in these sectors. This has profound implications for the design of sectoral regulatory and liability regimes, including associated features such as extended liability law, class actions and contingency fees. This book forms a major contribution to the academic debate on the comparative utility of regulatory and liability systems, on public versus private enforcement, and on mechanisms of behaviour control.

Smooth

Smooth
Author: Matt Burns
Publisher: Candlewick Press
Total Pages: 369
Release: 2020-06-16
Genre: Young Adult Fiction
ISBN: 1536211842

Kevin’s acne is horribly, hideously bad. Can a risky treatment fix his face — and his entire life? A witty and sharply observed debut. Fifteen-year-old Kevin has acne, and not just any acne. Stinging red welts, painful pustules, and massive whiteheads are ruining his life. In an act of desperation, he asks his dermatologist to prescribe him a drug with a dizzying list of possible side effects — including depression — and an obligatory monthly blood test. But when he meets Alex, a girl in the lab waiting room, blood test day quickly becomes his safe haven — something he sorely needs, since everyone, including his two best friends, is trying his last nerve. But as Kevin’s friendships slip further away and he discovers who Alex is outside of the lab, he realizes he's not sure about anything anymore. Are loneliness and self-doubt the side effects of his new acne meds? Or are they the side effects of being fifteen? Told in a bitingly funny first-person narration, this debut novel crackles with wry and wistful insights about the absurdities of high school, longing and heartbreak, and a body out of control. A surefire hit for teen boys and reluctant readers, Smooth gets under the skin of a tenth-grader who is changing — inside and out.

Principles and Practice of Clinical Trials

Principles and Practice of Clinical Trials
Author: Steven Piantadosi
Publisher: Springer Nature
Total Pages: 2573
Release: 2022-07-19
Genre: Medical
ISBN: 3319526367

This is a comprehensive major reference work for our SpringerReference program covering clinical trials. Although the core of the Work will focus on the design, analysis, and interpretation of scientific data from clinical trials, a broad spectrum of clinical trial application areas will be covered in detail. This is an important time to develop such a Work, as drug safety and efficacy emphasizes the Clinical Trials process. Because of an immense and growing international disease burden, pharmaceutical and biotechnology companies continue to develop new drugs. Clinical trials have also become extremely globalized in the past 15 years, with over 225,000 international trials ongoing at this point in time. Principles in Practice of Clinical Trials is truly an interdisciplinary that will be divided into the following areas: 1) Clinical Trials Basic Perspectives 2) Regulation and Oversight 3) Basic Trial Designs 4) Advanced Trial Designs 5) Analysis 6) Trial Publication 7) Topics Related Specific Populations and Legal Aspects of Clinical Trials The Work is designed to be comprised of 175 chapters and approximately 2500 pages. The Work will be oriented like many of our SpringerReference Handbooks, presenting detailed and comprehensive expository chapters on broad subjects. The Editors are major figures in the field of clinical trials, and both have written textbooks on the topic. There will also be a slate of 7-8 renowned associate editors that will edit individual sections of the Reference.

The Future of Drug Safety

The Future of Drug Safety
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 347
Release: 2007-03-27
Genre: Medical
ISBN: 0309103045

In the wake of publicity and congressional attention to drug safety issues, the Food and Drug Administration (FDA) requested the Institute of Medicine assess the drug safety system. The committee reported that a lack of clear regulatory authority, chronic underfunding, organizational problems, and a scarcity of post-approval data about drugs' risks and benefits have hampered the FDA's ability to evaluate and address the safety of prescription drugs after they have reached the market. Noting that resources and therefore efforts to monitor medications' riskâ€"benefit profiles taper off after approval, The Future of Drug Safety offers a broad set of recommendations to ensure that consideration of safety extends from before product approval through the entire time the product is marketed and used.