Introduction to Computational Cardiology

Introduction to Computational Cardiology
Author: Boris Ja. Kogan
Publisher: Springer Science & Business Media
Total Pages: 236
Release: 2009-12-09
Genre: Computers
ISBN: 0387766863

Introduction to Computational Cardiology provides a comprehensive, in-depth treatment of the fundamental concepts and research challenges involved in the mathematical modeling and computer simulation of dynamical processes in the heart, under normal and pathological conditions. About this textbook: - Presents descriptions of models used in both biology and medicine for discovering the mechanisms of heart function and dysfunction on several physiological scales across different species. - Provides several examples throughout the textbook and exercises at the end which facilitate understanding of basic concepts and introduces, for implementation, treated problems to parallel supercomputers. Introduction to Computational Cardiology serves as a secondary textbook or reference book for advanced-level students in computer science, electrical engineering, biomedical engineering, and cardiac electrophysiology. It is also suitable for researchers employing mathematical modeling and computer simulations of biomedical problems.

Computational Cardiology

Computational Cardiology
Author: Frank B. Sachse
Publisher: Springer
Total Pages: 364
Release: 2005-01-12
Genre: Medical
ISBN: 3540259260

This book is devoted to computer-based modeling in cardiology, by taking an educational point of view, and by summarizing knowledge from several, commonly considered delimited areas of cardiac research in a consistent way. First, the foundations and numerical techniques from mathematics are provided, with a particular focus on the finite element and finite differences methods. Then, the theory of electric fields and continuum mechanics is introduced with respect to numerical calculations in anisotropic biological media. In addition to the presentation of digital image processing techniques, the following chapters deal with particular aspects of cardiac modeling: cardiac anatomy, cardiac electro physiology, cardiac mechanics, modeling of cardiac electro mechanics. This book was written for researchers in modeling and cardiology, for clinical cardiologists, and for advanced students.

Modeling and Simulating Cardiac Electrical Activity

Modeling and Simulating Cardiac Electrical Activity
Author: David J. Christini
Publisher:
Total Pages: 0
Release: 2020
Genre: Electrocardiography
ISBN: 9780750320641

This book provides a thorough introduction to the topic of mathematical modeling of electrical activity in the heart, from molecular details of ionic channel dynamics to clinically derived patient-specific models. It discusses how cellular ionic models are formulated, introduces commonly used models and explains why there are so many different models available. The chapters cover modeling of the intracellular calcium handling that underlies cellular contraction as well as modeling molecular-level details of cardiac ion channels, and also focus on specialized topics such as cardiomyocyte energetics and signalling pathways. It is an excellent resource for experienced and specialised researchers in the field, but also biological scientists with a limited background in mathematical modelling and computational methods. Part of Biophysical Society-IOP series.

Computing the Electrical Activity in the Heart

Computing the Electrical Activity in the Heart
Author: Joakim Sundnes
Publisher: Springer Science & Business Media
Total Pages: 323
Release: 2007-06-26
Genre: Computers
ISBN: 3540334378

This book describes mathematical models and numerical techniques for simulating the electrical activity in the heart. It gives an introduction to the most important models, followed by a detailed description of numerical techniques. Particular focus is on efficient numerical methods for large scale simulations on both scalar and parallel computers. The results presented in the book will be of particular interest to researchers in bioengineering and computational biology.

Mathematical Cardiac Electrophysiology

Mathematical Cardiac Electrophysiology
Author: Piero Colli Franzone
Publisher: Springer
Total Pages: 410
Release: 2014-10-30
Genre: Mathematics
ISBN: 3319048015

This book covers the main mathematical and numerical models in computational electrocardiology, ranging from microscopic membrane models of cardiac ionic channels to macroscopic bidomain, monodomain, eikonal models and cardiac source representations. These advanced multiscale and nonlinear models describe the cardiac bioelectrical activity from the cell level to the body surface and are employed in both the direct and inverse problems of electrocardiology. The book also covers advanced numerical techniques needed to efficiently carry out large-scale cardiac simulations, including time and space discretizations, decoupling and operator splitting techniques, parallel finite element solvers. These techniques are employed in 3D cardiac simulations illustrating the excitation mechanisms, the anisotropic effects on excitation and repolarization wavefronts, the morphology of electrograms in normal and pathological tissue and some reentry phenomena. The overall aim of the book is to present rigorously the mathematical and numerical foundations of computational electrocardiology, illustrating the current research developments in this fast-growing field lying at the intersection of mathematical physiology, bioengineering and computational biomedicine. This book is addressed to graduate student and researchers in the field of applied mathematics, scientific computing, bioengineering, electrophysiology and cardiology.

Computational And Mathematical Methods In Cardiovascular Physiology

Computational And Mathematical Methods In Cardiovascular Physiology
Author: Liang Zhong
Publisher: World Scientific
Total Pages: 458
Release: 2019-04-26
Genre: Medical
ISBN: 9813270659

Cardiovascular diseases (CVD) including heart diseases, peripheral vascular disease and heart failure, account for one-third of deaths throughout the world. CVD risk factors include systolic blood pressure, total cholesterol, high-density lipoprotein cholesterol, and diabetic status. Clinical trials have demonstrated that when modifiable risk factors are treated and corrected, the chances of CVD occurring can be reduced. This illustrates the importance of this book's elaborate coverage of cardiovascular physiology by the application of mathematical and computational methods.This book has literally transformed Cardiovascular Physiology into a STEM discipline, involving (i) quantitative formulations of heart anatomy and physiology, (ii) technologies for imaging the heart and blood vessels, (iii) coronary stenosis hemodynamics measure by means of fractional flow reserve and intervention by grafting and stenting, (iv) fluid mechanics and computational analysis of blood flow in the heart, aorta and coronary arteries, and (v) design of heart valves, percutaneous valve stents, and ventricular assist devices.So how is this mathematically and computationally configured landscape going to impact cardiology and even cardiac surgery? We are now entering a new era of mathematical formulations of anatomy and physiology, leading to technological formulations of medical and surgical procedures towards more precise medicine and surgery. This will entail reformatting of (i) the medical MD curriculum and courses, so as to educate and train a new generation of physicians who are conversant with medical technologies for applying into clinical care, as well as (ii) structuring of MD-PhD (Computational Medicine and Surgery) Program, to train competent medical and surgical specialists in precision medical care and patient-specific surgical care.This book provides a gateway for this new emerging scenario of (i) science and engineering based medical educational curriculum, and (ii) technologically oriented medical and surgical procedures. As such, this book can be usefully employed as a textbook for courses in (i) cardiovascular physiology in both the schools of engineering and medicine of universities, as well as (ii) cardiovascular engineering in biomedical engineering departments worldwide.

Mathematical Modelling of the Human Cardiovascular System

Mathematical Modelling of the Human Cardiovascular System
Author: Alfio Quarteroni
Publisher: Cambridge University Press
Total Pages: 291
Release: 2019-05-09
Genre: Mathematics
ISBN: 110848039X

Addresses the mathematical and numerical modelling of the human cardiovascular system, from patient data to clinical applications.

Cardiovascular Mathematics

Cardiovascular Mathematics
Author: Luca Formaggia
Publisher: Springer Science & Business Media
Total Pages: 528
Release: 2010-06-27
Genre: Mathematics
ISBN: 8847011523

Mathematical models and numerical simulations can aid the understanding of physiological and pathological processes. This book offers a mathematically sound and up-to-date foundation to the training of researchers and serves as a useful reference for the development of mathematical models and numerical simulation codes.

Cardiac Computed Tomography

Cardiac Computed Tomography
Author: Milind Y. Desai
Publisher: Lippincott Williams & Wilkins
Total Pages: 505
Release: 2011-12-21
Genre: Medical
ISBN: 1451171048

Technologic advances in imaging now allow cardiologists to diagnose, noninvasively, a wide range of cardiac disorders, from subclinical atherosclerosis to obstructive coronary artery disease. This 500+ Question & Answer review book serves as the board prep product for all cardiologists/fellows/radiologists interested in certifying in this rapidly expanding area. All aspects of cardiovascular CT principles and physics, methodologies, and clinical practice are covered. Features Include: • Cost-effective board preparation; • MCQs that mimic the CCT boards; • Review questions in CT physics, study acquisition, and interpretation; • Online access to video clips and over 500 Q&As.