International Ethical Guidelines for Biomedical Research Involving Human Subjects

International Ethical Guidelines for Biomedical Research Involving Human Subjects
Author: Council for International Organizations of Medical Sciences
Publisher: World Health Organization
Total Pages: 116
Release: 2002
Genre: Bioethics
ISBN:

The present text is the revised/updated version of the CIOMS International Ethical Guidelines for Biomedical Research Involving Human Subjects. It consists of 21 guidelines with commentaries. A prefatory section outlines the historical background and the revision process and includes an introduction an account of earlier instruments and guidelines a statement of ethical principles and a preamble. An Appendix lists the items to be included in the research protocol to be submitted for scientific and ethical review and clearance. The Guidelines relate mainly to ethical justification and scientific validity of research; ethical review; informed consent; vulnerability - of individuals groups communities and populations; women as research subjects; equity regarding burdens and benefits; choice of control in clinical trials; confidentiality; compensation for injury; strengthening of national or local capacity for ethical review; and obligations of sponsors to provide health-care services. They are designed to be of use to countries in defining national policies on the ethics of biomedical research involving human subjects applying ethical standards in local circumstances and establishing or improving ethical review mechanisms. A particular aim is to reflect the conditions and the needs of low-resource countries and the implications for multinational or transnational research in which they may be partners.

A Practical Guide to Biomedical Research

A Practical Guide to Biomedical Research
Author: Peter Agger
Publisher: Springer
Total Pages: 185
Release: 2017-10-27
Genre: Medical
ISBN: 3319635824

This book advises and supports novice researchers in taking their first steps into the world of scientific research. Through practical tips and tricks presented in a clear, concise and step-wise manner, the book describes the entire research process from idea to publication. It also gives the reader insight into the vast opportunities a research career can provide. The books target demographic is aspiring researchers within the biomedical professions, be it medical students, young doctors, nurses, engineers, physiotherapists etc. The book will help aspirational inexperienced researchers turn their intentions into actions, providing crucial guidance for successful entry into the field of biomedical research.

The Ethics of Biomedical Research

The Ethics of Biomedical Research
Author: Baruch A. Brody
Publisher: Oxford University Press, USA
Total Pages: 412
Release: 1998
Genre: Medical
ISBN: 9780195090079

A broad critical review of national policies on biomedical research - human, epidemiologic, clinical trials, genetic, reproductive, etc.

Research as Development

Research as Development
Author: Salla Sariola
Publisher: Cornell University Press
Total Pages: 206
Release: 2019-03-15
Genre: Technology & Engineering
ISBN: 1501733621

In Research as Development, Salla Sariola and Bob Simpson show how international collaboration operates in a setting that is typically portrayed as "resource-poor" and "scientifically lagging." Based on their long-term fieldwork in Sri Lanka, Sariola and Simpson bring into clear ethnographic focus the ways international scientific collaborations feature prominently in the pursuit of global health in which research operates "as" development and not merely "for" it. The authors follow the design, inception, and practice of two clinical trials: one a global health charity funded trial and the other a pharmaceutical industry-sponsored trial. Research as Development situates these two trials within their historical, political and cultural contexts and thus counters the idea that local actors are merely passive recipients of new technical and scientific rationalities. While social studies of clinical trials are beginning to be an established niche in academic writing, Research as Development helps fill important gaps in the literature through its examination of clinical research situated in cultures in low-income settings. Research as Development is noteworthy for the way it highlights the critical and creative role that local researchers play in establishing international collaborations and making them work into locally viable forms. The volume shows how these clinical and research interactions bring about changes in culture, technologies and expertise in Sri Lanka, contexts that have not previously been written about in any detail.

International Ethical Guidelines for Health-Related Research Involving Humans

International Ethical Guidelines for Health-Related Research Involving Humans
Author: Council for International Organizations of Medical Sciences (CIOMS)
Publisher: World Health Organization
Total Pages: 0
Release: 2017-01-31
Genre: Bioethics
ISBN: 9789290360889

"In the new 2016 version of the ethical guidelines, CIOMS provides answers to a number of pressing issues in research ethics. The Council does so by stressing the need for research having scientific and social value, by providing special guidelines for health-related research in low-resource settings, by detailing the provisions for involving vulnerable groups in research and for describing under what conditions biological samples and health-related data can be used for research."--Page 4 de la couverture.

Network Pharmacology

Network Pharmacology
Author: Shao Li
Publisher: Springer Nature
Total Pages: 480
Release: 2021-09-29
Genre: Medical
ISBN: 9811607532

This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.

The Common Marmoset in Captivity and Biomedical Research

The Common Marmoset in Captivity and Biomedical Research
Author: Robert P. Marini
Publisher: Academic Press
Total Pages: 572
Release: 2018-11-19
Genre: Science
ISBN: 012811830X

The Common Marmoset in Captivity and Biomedical Research is the first text dedicated exclusively to this species,filling an urgent need for an encyclopedic compilation of the existing information. Sponsored by the AmericanCollege of Laboratory Animal Medicine as part of its authoritative Blue Book series, the book covers the biology,management, diseases, and clinical and research applications of this important species. The common marmoset(Callithrix jacchus) has come of age in the scientific community as a behaviorally complex, cognitively advanced,small, prolific, and easily maintained nonhuman primate with many of the advantages of larger animals, such asmacaques, but without the attendant physical and zoonotic risks. Marmosets are currently being used in diverse areas of inquiry, including vision and auditory research, infectious disease, cognitive neuroscience, behavior, reproductive biology, toxicology and drug development, and aging. Themarmoset genome has been sequenced and there is currently an intensive effort to apply gene editing technologies to the species. The creation of transgenic marmosets will provide researchers with a small nonhuman primatemodel to study a number of poorly understood disorders, like autism. - Presents a complete view of the marmoset, covering their biology and management, diseases and clinical applications, and research applications - Includes contributions from renowned and international authors and editors - Provides the first authoritative and comprehensive treatment of marmosets in biomedical research as part of the ACLAM Series

Ethical Issues in International Biomedical Research

Ethical Issues in International Biomedical Research
Author: James V. Lavery
Publisher:
Total Pages: 401
Release: 2007
Genre: Medical
ISBN: 0195179226

Ethical Issues in International Biomedical Research is the definitive book on the ethics of research involving human subjects in developing countries. Using 21 actual case studies, it covers the most controversial topics, including the ethics of placebo research in Africa, what benefits should be provided to the community after completion of a research trial, how to address conflicts between IRBs in developed and developing countries, and undue inducement of poor people in developing countries. Each case is accompanied by two expert commentaries, written by many of the worlds leading experts in bioethics as well as new voices with research experience in developing countries. No other volume has this scope. Students in bioethics, public and international health, and ethics will find this book particularly useful.