From biology to economics to information theory, the theme of interdependence is in the air, framing our experiences of all sorts of everyday phenomena. Indeed, the network may be the ascendant metaphor of our time. Yet precisely because the language of interdependence has become so commonplace as to be almost banal, we miss some of its most surprising and far-reaching implications. In Interdependence, biologist Kriti Sharma offers a compelling alternative to the popular view that interdependence simply means independent things interacting. Sharma systematically shows how interdependence entails the mutual constitution of one thing by another—how all things come into being only in a system of dependence on others. In a step-by-step account filled with vivid examples, Sharma shows how a coherent view of interdependence can help make sense not only of a range of everyday experiences but also of the most basic functions of living cells. With particular attention to the fundamental biological problem of how cells pick up signals from their surroundings, Sharma shows that only an account which replaces the perspective of “individual cells interacting with external environments” with one centered in interdependent, recursive systems can adequately account for how life works. This book will be of interest to biologists and philosophers, to theorists of science, of systems, and of cybernetics, and to anyone curious about how life works. Clear, concise, and insightful, Interdependence: Biology and Beyond explicitly offers a coherent and practical philosophy of interdependence and will help shape what interdependence comes to mean in the twenty-first century.