Integrated Virus Detection

Integrated Virus Detection
Author: Charles H. Wick
Publisher: CRC Press
Total Pages: 260
Release: 2014-11-13
Genre: Medical
ISBN: 1482230054

Multiple viruses can be detected concurrently using the Integrated Virus Detection System (IVDS). Integrated Virus Detection describes this technology and provides many examples of applications including a chapter on viruses found in honeybees with descriptions of seasonal and yearly variation. This straightforward technology can be used to detect known, unknown, and unsequenced viruses collected from environmental and other complex biological sources. This book summarizes more than ten US patents issued for the invention of the IVDS, which is the common name of the electrospray–differential mobility analyzer method. The IVDS is powering mankind’s ability to rapidly detect, measure, and monitor viruses as well as virus-like particles. Three facts make rapid detection possible: virus size, which ranges from 20 to 800 nm.; disparity in each virus species’ particle size thus allowing size data to be used for detection and preliminary identification; and the fact that virus particle density is distinct from other nanoparticles. The IVDS can ascertain the absence of virion particles, thus presenting compelling evidence of a true negative, which is useful in verifying decontamination and other processes. In addition, large numbers of samples may be processed in an automated fashion, providing an excellent means to prescreen them for judicious targeting of subsequent tests such as PCR or the discriminating method for identifying microbes, which is mass spectrometry proteomics.* The book is helpful to anyone interested in virus detection, especially in situations where many viral types may coexist. *Identifying Microbes by Mass Spectrometry Proteomics (CRC Press 2013)

Virus Detection

Virus Detection
Author: Charles H. Wick
Publisher: CRC Press
Total Pages: 158
Release: 2023-05-03
Genre: Science
ISBN: 1000868303

Viruses do not behave as other microbes; their life cycles require infecting healthy cells, commandeering their cellular apparatus, replicating and then killing the host cell. Methods for virus detection and identification have been developed only in the past few decades. These recently developed methods include molecular, physical, and proteomic techniques. All these approaches (Electron Microscopy, Molecular, Direct Counting, and Mass Spectrometry Proteomics) to detection and identification are reviewed in this succinct volume. It is written in approachable language with enough detail for trained professionals to follow and want to recommend to others. Key Features Covers common detection methods Reviews the history of detection from antiquity to the present Documents the strengths and weaknesses of various detection methods Describes how to detect newly discovered viruses Recommends specific applications for clinical, hospital, environmental, and public health uses

Comprehensive Biotechnology

Comprehensive Biotechnology
Author:
Publisher: Elsevier
Total Pages: 4876
Release: 2019-07-17
Genre: Science
ISBN: 0444640479

Comprehensive Biotechnology, Third Edition, Six Volume Set unifies, in a single source, a huge amount of information in this growing field. The book covers scientific fundamentals, along with engineering considerations and applications in industry, agriculture, medicine, the environment and socio-economics, including the related government regulatory overviews. This new edition builds on the solid basis provided by previous editions, incorporating all recent advances in the field since the second edition was published in 2011. Offers researchers a one-stop shop for information on the subject of biotechnology Provides in-depth treatment of relevant topics from recognized authorities, including the contributions of a Nobel laureate Presents the perspective of researchers in different fields, such as biochemistry, agriculture, engineering, biomedicine and environmental science

Integrated Virus Detection

Integrated Virus Detection
Author: Charles H Wick
Publisher: CRC Press
Total Pages: 0
Release: 2021-03-30
Genre: Medical
ISBN: 9780367658939

Multiple viruses can be detected concurrently using the Integrated Virus Detection System (IVDS). Integrated Virus Detection describes this technology and provides many examples of applications including a chapter on viruses found in honeybees with descriptions of seasonal and yearly variation. This straightforward technology can be used to detect known, unknown, and unsequenced viruses collected from environmental and other complex biological sources. This book summarizes more than ten US patents issued for the invention of the IVDS, which is the common name of the electrospray-differential mobility analyzer method. The IVDS is powering mankind's ability to rapidly detect, measure, and monitor viruses as well as virus-like particles. Three facts make rapid detection possible: virus size, which ranges from 20 to 800 nm.; disparity in each virus species' particle size thus allowing size data to be used for detection and preliminary identification; and the fact that virus particle density is distinct from other nanoparticles. The IVDS can ascertain the absence of virion particles, thus presenting compelling evidence of a true negative, which is useful in verifying decontamination and other processes. In addition, large numbers of samples may be processed in an automated fashion, providing an excellent means to prescreen them for judicious targeting of subsequent tests such as PCR or the discriminating method for identifying microbes, which is mass spectrometry proteomics.* The book is helpful to anyone interested in virus detection, especially in situations where many viral types may coexist. *Identifying Microbes by Mass Spectrometry Proteomics (CRC Press 2013)

Virus Discovery by Metagenomics: The (Im)possibilities

Virus Discovery by Metagenomics: The (Im)possibilities
Author: Bas E. Dutilh
Publisher: Frontiers Media SA
Total Pages: 218
Release: 2017-10-25
Genre:
ISBN: 2889453081

Since the late 1800s, the discovery of new viruses was a gradual process. Viruses were described one by one using a suite of techniques such as (electron) microscopy and viral culture. Investigators were usually interested in a disease state within an organism, and expeditions in viral ecology were rare. The advent of metagenomics using high-throughput sequencing has revolutionized not only the rate of virus discovery, but also the nature of the discoveries. For example, the viral ecology and etiology of many human diseases are being characterized, non-pathogenic viral commensals are ubiquitous, and the description of environmental viromes is making progress. This Frontiers in Virology Research Topic showcases how metagenomic and bioinformatic approaches have been combined to discover, classify and characterize novel viruses.

Viral Metagenomics

Viral Metagenomics
Author: Vitantonio Pantaleo
Publisher: Springer Nature
Total Pages: 293
Release: 2023-12-07
Genre: Medical
ISBN: 1071635158

This second edition volume expands on the previous edition with discussions about the latest viral metagenomics aspects covering a range of different specimens such as soil, freshwater, wastewater, fecal samples, blood plasma, clinical tissues, fungi, and herbarium samples. Chapters also look at different viral groups including archaeal viruses, eukaryotic viruses, phages, mycoviruses, and circular DNA viruses. Techniques required for studying the three viral metagenomic steps of samples processing, library construction, and analysis of data are also discussed. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Vital Metagenomics: Methods and Protocols, Second Edition is a valuable resource for researchers who are interested in learning more about this important and developing field.

Human Retroviruses

Human Retroviruses
Author: Bryan Cullen
Publisher: Oxford University Press
Total Pages: 220
Release: 1993
Genre: Gene Expression Regulation.
ISBN: 9780199633821

The first book to specifically cover the molecular biology of retroviruses - of immense importance since the high profile of HIV. International contributors provide detailed reviews of the latest knowledge. An excellent text for both medical and non-medical researchers, it also serves as an illuminating introduction for scientists active in other areas.

Microbial Diversity in Honeybees

Microbial Diversity in Honeybees
Author: Charles H. Wick
Publisher: CRC Press
Total Pages: 275
Release: 2021-05-20
Genre: Science
ISBN: 1000377121

Honeybees are an important link in our food chain because they are major pollinators of food crops. In recent years, honeybee populations have declined precipitously perhaps due to changes in their microbiome. This book describes and identifies the bee microbiome using a proteomics technology. Chapters include the detection and identification of microbes found in honeybees collected around the United States. This book contains new data and illustrates the rich diversity of microbes as collected by honeybees. It is a must read for everyone concerned about the honeybee and working in the industry.