Network Pharmacology

Network Pharmacology
Author: Shao Li
Publisher: Springer Nature
Total Pages: 480
Release: 2021-09-29
Genre: Medical
ISBN: 9811607532

This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.

Phytochemistry of Medicinal Plants

Phytochemistry of Medicinal Plants
Author: John T. Arnason
Publisher: Springer Science & Business Media
Total Pages: 369
Release: 2013-11-11
Genre: Science
ISBN: 1489917780

Phytochemicals from medicinal plants are receiving ever greater attention in the scientific literature, in medicine, and in the world economy in general. For example, the global value of plant-derived pharmaceuticals will reach $500 billion in the year 2000 in the OECD countries. In the developing countries, over-the-counter remedies and "ethical phytomedicines," which are standardized toxicologically and clinically defined crude drugs, are seen as a promising low cost alternatives in primary health care. The field also has benefited greatly in recent years from the interaction of the study of traditional ethnobotanical knowledge and the application of modem phytochemical analysis and biological activity studies to medicinal plants. The papers on this topic assembled in the present volume were presented at the annual meeting of the Phytochemical Society of North America, held in Mexico City, August 15-19, 1994. This meeting location was chosen at the time of entry of Mexico into the North American Free Trade Agreement as another way to celebrate the closer ties between Mexico, the United States, and Canada. The meeting site was the historic Calinda Geneve Hotel in Mexico City, a most appropriate site to host a group of phytochemists, since it was the address of Russel Marker. Marker lived at the hotel, and his famous papers on steroidal saponins from Dioscorea composita, which launched the birth control pill, bear the address of the hotel.

Herbal Medicine

Herbal Medicine
Author: Iris F. F. Benzie
Publisher: CRC Press
Total Pages: 500
Release: 2011-03-28
Genre: Health & Fitness
ISBN: 1439807167

The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef

Personalized Machine Learning

Personalized Machine Learning
Author: Julian McAuley
Publisher: Cambridge University Press
Total Pages: 338
Release: 2022-02-03
Genre: Computers
ISBN: 1009008579

Every day we interact with machine learning systems offering individualized predictions for our entertainment, social connections, purchases, or health. These involve several modalities of data, from sequences of clicks to text, images, and social interactions. This book introduces common principles and methods that underpin the design of personalized predictive models for a variety of settings and modalities. The book begins by revising 'traditional' machine learning models, focusing on adapting them to settings involving user data, then presents techniques based on advanced principles such as matrix factorization, deep learning, and generative modeling, and concludes with a detailed study of the consequences and risks of deploying personalized predictive systems. A series of case studies in domains ranging from e-commerce to health plus hands-on projects and code examples will give readers understanding and experience with large-scale real-world datasets and the ability to design models and systems for a wide range of applications.

The Plant Hunter

The Plant Hunter
Author: Cassandra Leah Quave
Publisher: Penguin
Total Pages: 385
Release: 2022-06-14
Genre: Biography & Autobiography
ISBN: 1984879138

The uplifting, adventure-filled memoir of one groundbreaking scientist’s quest to develop new ways to fight illness and disease through the healing powers of plants. “A fascinating and deeply personal journey.” ­—Amy Stewart, author of Wicked Plants and The Drunken Botanist Traveling by canoe, ATV, mule, airboat, and on foot, Dr. Cassandra Quave has conducted field research everywhere from the flooded forests of the remote Amazon to the isolated mountaintops in Albania and Kosovo—all in search of natural compounds, long-known to traditional healers, that could help save us all from the looming crisis of untreatable superbugs. Dr. Quave is a leading medical ethnobotanist—someone who identifies and studies plants that may be able to treat antimicrobial resistance and other threatening illnesses—helping to provide clues for the next generation of advanced medicines. And as a person born with multiple congenital defects of her skeletal system, she's done it all with just one leg. In The Plant Hunter, Dr. Quave weaves together science, botany, and memoir to tell us the extraordinary story of her own journey.

Ethnopharmacology

Ethnopharmacology
Author: Michael Heinrich
Publisher: John Wiley & Sons
Total Pages: 464
Release: 2015-07-29
Genre: Medical
ISBN: 1118930738

Ethnopharmacology is one of the world’s fastest-growing scientific disciplines encompassing a diverse range of subjects. It links natural sciences research on medicinal, aromatic and toxic plants with socio-cultural studies and has often been associated with the development of new drugs. The Editors of Ethnopharmacology have assembled an international team of renowned contributors to provide a critical synthesis of the substantial body of new knowledge and evidence on the subject that has emerged over the past decade. Divided into three parts, the book begins with an overview of the subject including a brief history, ethnopharmacological methods, the role of intellectual property protection, key analytical approaches, the role of ethnopharmacology in primary/secondary education and links to biodiversity and ecological research. Part two looks at ethnopharmacological contributions to modern therapeutics across a range of conditions including CNS disorders, cancer, bone and joint health and parasitic diseases. The final part is devoted to regional perspectives covering all continents, providing a state-of-the –art assessment of the status of ethnopharmacological research globally. A comprehensive, critical synthesis of the latest developments in ethnopharmacology. Includes a section devoted to ethnopharmacological contributions to modern therapeutics across a range of conditions. Contributions are from leading international experts in the field. This timely book will prove invaluable for researchers and students across a range of subjects including ethnopharmacology, ethnobotany, medicinal plant research and natural products research. Ethnopharmacology- A Reader is part of the ULLA Series in Pharmaceutical Sciences www.ullapharmsci.org

Plants For Novel Drug Molecules

Plants For Novel Drug Molecules
Author: Bikarma Singh
Publisher: New India Publishing Agency
Total Pages: 8
Release: 2020-11-24
Genre: Medical
ISBN: 9389571944

The present book is based on twenty five excellent scientific contributions of seventy researchers from topmost research organizations. The book begin with plants used in Sowa-Rigpa system of food and medicine, followed by traditional uses of plants as medicine among Khasi tribe living in northeast India. This compilation contains several research techniques highlighting methods and analysis of documented data, and procedure for scientific validation of findings. Methods for assessing traditional knowledge of highly threatened plants such as Hodgsoniaheteroclita, pharmacological applications of family asteraceae, ethnobotany of family apiaceae, plants used in managing leucorrhea, plants as animal care, phytochemistry of Arisaemajacquemontii, Andrographispaniculata, Blumealacera, Boerhaaviadiffusa, Hemidesmusindicus, Pterocarpussantalinus, Rauwolfiaserpentina, Rauwolfiatetraphylla, and several other ethnobotanical and ethnopharmacological parameters used in studying current science is described in this book. Besides, it is followed by several research topics focused to the clinical arena, plants used in relation to cancer, diabetes, skin disorders and many other aspects relates to animal and human health care. Today's food supplements derived from plants are of high demand, and this compilation also highlighted several plants used as nutraceuticals. It has been observed that herbs contain many bioactive compounds with powerful antioxidant properties as evidence from the scientific data, and few research on lianas, lichens and role of allylisothiocyanate as a bioprotective agent also discussed added more value to this compilations. Focused theme such as ethnobotanical trends and techniques, phytochemistry, biological activities, ethnopharmacology and clinical studies is adding and contributing a lots value to this book in discovering leads for medicine formulations.