Inheritance of Crises and Dysfunction

Inheritance of Crises and Dysfunction
Author: James J. Maiwurm
Publisher: iUniverse
Total Pages: 185
Release: 2020-07-27
Genre: Fiction
ISBN: 1663204675

Inheritance of Crises and Dysfunction is a novel about the daunting challenges waiting at home and abroad for the next US Administration, the search for innovative responses and people asked to implement solutions. In addition to global and domestic political issues, the book grapples with the stubborn trauma that accompanies the loss of a spouse, the pain of moving, the mixed emotions associated with contemplating retirement, and the psychological need to remain relevant and connected as one grows older. It is designed to be thought-provoking as well as entertaining, and light enough to stir an occasional laugh or smile. The book opens on inauguration day in 2021. Through the eyes of the protagonist, “’Salt Pepper,” whose career included stints with the US Government and a Washington law firm, it portrays the deep disagreements and partisanship that divide our citizens from one another and their Government, and the US from the rest of the world. Salt thinks he has retired and moved to his ancestral farm near the foot of the Blue Ridge mountains in rural Virginia. Then an old acquaintance, who is about to become the Secretary of State in a new Administration, talks him into accepting a temporary clandestine diplomatic role that takes Salt and a new and able female colleague to the White House, London, Berlin, and Prague and into sensitive meetings with diplomats there and from the Middle East. With roots in history, current events and human nature, the book provides insight into an inheritance of international disarray, toxic domestic politics, the harmful dissonance emanating from our battered small town and rural America, small business and manufacturing, as well as global clamor for US leadership. The crises and dysfunction are not imaginary; neither is the need for leaders willing to grasp nettles and contribute to much needed solutions, even when risky and inconvenient.

Inheritance of Crises and Dysfunction

Inheritance of Crises and Dysfunction
Author: James J. Maiwurm
Publisher:
Total Pages: 0
Release: 2023-09-22
Genre: Political Science
ISBN: 9781958518595

Inheritance of Crises and Dysfunction is a novel about the daunting challenges waiting at home and abroad for the next US Administration, the search for innovative responses and people asked to implement solutions. In addition to global and domestic political issues, the book grapples with the stubborn trauma that accompanies the loss of a spouse, the pain of moving, the mixed emotions associated with contemplating retirement, and the psychological need to remain relevant and connected as one grows older. It is designed to be thought-provoking as well as entertaining, and light enough to stir an occasional laugh or smile. The book opens on inauguration day in 2021. Through the eyes of the protagonist, "'Salt Pepper," whose career included stints with the US Government and a Washington law firm, it portrays the deep disagreements and partisanship that divide our citizens from one another and their Government, and the US from the rest of the world. Salt thinks he has retired and moved to his ancestral farm near the foot of the Blue Ridge mountains in rural Virginia. Then an old acquaintance, who is about to become the Secretary of State in a new Administration, talks him into accepting a temporary clandestine diplomatic role that takes Salt and a new and able female colleague to the White House, London, Berlin, and Prague and into sensitive meetings with diplomats there and from the Middle East. With roots in history, current events, and human nature, the book provides insight into an inheritance of international disarray, toxic domestic politics, the harmful dissonance emanating from our battered small town and rural America, small business and manufacturing, as well as global clamor for US leadership. The crises and dysfunction are not imaginary; neither is the need for leaders willing to grasp nettles and contribute to much-needed solutions, even when risky and inconvenient.

Emery and Rimoin's Essential Medical Genetics

Emery and Rimoin's Essential Medical Genetics
Author: David L. Rimoin
Publisher: Elsevier
Total Pages: 647
Release: 2013-05-15
Genre: Science
ISBN: 0124169821

For decades, Emery and Rimoin’s Principles and Practice of Medical Genetics has provided the ultimate source for practicing clinicians to learn how the study of genetics can be integrated into practice. Developed in parallel to the sixth edition, and featuring 174 original contributions from the many authors of the full set, this one volume work expertly condenses and synthesizes the most clinically relevant content, for convenient desk reference. Helping to bridge the gap between high-level molecular genetics and individual application, it follows the multi-volume set in encompassing scientific fundamentals, full spectrum discussion of major inherited disorders, and actionable therapies. Clinically oriented information is supported by concise descriptions of the principles of genetics, research approaches, and analytics to embrace the evolving population of students, researchers, and practitioners who are integrating their work to provide advanced diagnosis, prevention and treatment of human disease. This print volume is complemented and enhanced with online access to the complete text, online-only references, and high quality illustrations on www.expertconsult.com. Features 174 summarized contributions concisely discussing advances in cancer genetics, genomic technologies, and molecular genetics Contains hundreds of full colour illustrations supporting users with identification, concept illustration, and method processing Enhanced with full text online access, high quality illustrations, and online-only references at www.expertconsult.com

The Obstetric Hematology Manual

The Obstetric Hematology Manual
Author: Sue Pavord
Publisher: Cambridge University Press
Total Pages: 362
Release: 2018-02-08
Genre: Medical
ISBN: 1108548377

Understand the rapidly growing complexities of obstetric hematology and high-risk pregnancy management, with experts in the field. Now in its second edition, this comprehensive and essential guide focuses on providing the best support for patients and clinical staff, to prevent serious complications in pregnancy and the post-partum period for both mother and baby. Wide-ranging and detailed, the guide offers discussions on basic principles of best care, through to tackling lesser-known hematological conditions, such as cytopenias and hemoglobinopathies. Updated with color illustrations, cutting-edge research, accurate blood film reproductions, and practical case studies, the revised edition places invaluable advice into everyday context. This unique resource is essential reading for trainees and practitioners in obstetrics, anesthesia, and hematology, as well as midwives, nurses, and laboratory staff. Clarifying difficult procedures for disease prevention, the guide ensures safety when the stakes are high. Reflecting current evidence-based guidelines, the updated volume is key to improving pregnancy outcomes worldwide.

Genetic Disorders and the Fetus

Genetic Disorders and the Fetus
Author: Aubrey Milunsky
Publisher: John Wiley & Sons
Total Pages: 1216
Release: 2015-11-09
Genre: Medical
ISBN: 1118981529

Genetic Disorders and the Fetus: Diagnosis, Prevention and Treatment, Seventh Edition is the eagerly awaited new edition of the discipline-leading text that has been at the forefront of diagnosis, prevention, and treatment of fetal genetic disorders for over 36 years. The seventh edition continues the long-established tradition of excellence that has become synonymous with this text. The book builds on the foundations of preconception and prenatal genetic counseling and the original pillars of prenatal diagnosis while also providing authoritative coverage of exciting developments in non-invasive genetic testing and rapidly developing molecular techniques, including microarray analysis and next generation sequencing, that are revolutionizing the field. Chapters are once again authored by internationally recognized authorities in the field of prenatal diagnosis. The editors have added three entirely new chapters to this edition to complement the complete revision of existing content. The three new chapters focus on non-invasive prenatal screening, placental genetics, and the psychology of prenatal and perinatal grief. The broad-ranging coverage and international scope will ensure that the new edition maintains its role as the major repository for information on all aspects of prenatal diagnosis. The editors have brought together an invaluable collection of evidence-based facts bolstered by knowledge and decades of experience in the field. Genetic Disorders and the Fetus: Diagnosis, Prevention and Treatment, 7th Edition is a timely update to this world-leading text.

Paroxysmal Movement Disorders

Paroxysmal Movement Disorders
Author: Kapil D. Sethi
Publisher: Springer Nature
Total Pages: 145
Release: 2020-11-18
Genre: Medical
ISBN: 3030537218

This book addresses the challenges in the differential diagnosis and management of paroxysmal movement disorders. It provides the latest information on the genetics and pathophysiology, neurophysiology and neuroimaging of the core group of disorders in the field, namely the paroxysmal dyskinesias (PxD). Focused and concise, this guide features chapters that discuss other conditions that may be paroxysmal such as, episodic ataxia, startle syndromes and other more complicated groups of paroxysmal movement disorders such as ATP1A3 spectrum disorders. A chapter on secondary (acquired) paroxysmal dyskinesia highlights medical and other disorders that may result in paroxysmal dyskinesia. The book features a particularly nuanced chapter that discusses recent discoveries in the genetic aspects of PxD, relaying that paroxysmal dyskinesias are not channelpathies, but in fact are synaptophies and transportopathies. Additionally, expertly written chapters are supplemented by high quality images, tables, and videos. Paroxysmal Movement Disorders: A Practical Guide is primarily written to educate the reader on how to make a syndromic diagnosis of paroxysmal movement disorders and how to build the diagnostic work-up accordingly, as well as how to manage patients with paroxysmal movement disorders.

Atlas of Inherited Metabolic Diseases

Atlas of Inherited Metabolic Diseases
Author: William L Nyhan
Publisher: CRC Press
Total Pages: 871
Release: 2020-07-14
Genre: Medical
ISBN: 1138196606

In a field where even experts may find that years have elapsed since they last encountered a child with a given disorder, it is essential for the clinician to have a comprehensive source of practical and highly illustrated information covering the whole spectrum of metabolic disease to refer to. The content is divided into sections of related disorders, including disorders of amino acid metabolism, lipid storage disorders, and mitochondrial diseases for ease of reference, with an introductory outline where appropriate summarizing the biochemical features and general management issues. Within the sections, each chapter deals with an individual disease, opening with a useful summary of major phenotypic expression including clear and helpful biochemical pathways, identifying for the reader exactly where the defect occurs. Throughout the book, plentiful photographs, often showing extremely rare disorders, are an invaluable aid to diagnosis. Key Features • Fully updated to incorporate all new developments in the field • Brand new chapters cover methylmalonic aciduria of ACSF3 deficiency, branched chain keto acid dehydrogenase deficiency, serine deficiencies, purine nucleoside phosphorylase deficiency, antiquitin deficiency, and others • Excellent and detailed clinical descriptions, with numerous valuable hints and suggestions for management • Helpful explanatory algorithms and decision trees, and high-quality illustrative material including biochemical pathways and an unrivaled photographic collection, which enhance clinical applicability The fourth edition of this highly regarded book, authored by two of the foremost authorities in pediatric metabolic medicine, continues to provide incomparable insight into the problems associated with metabolic diseases and remains invaluable to pediatricians, geneticists, and general clinicians worldwide.

Robbins Essential Pathology E-Book

Robbins Essential Pathology E-Book
Author: Vinay Kumar
Publisher: Elsevier Health Sciences
Total Pages: 451
Release: 2020-04-22
Genre: Medical
ISBN: 0323640265

The newest addition to the highly regarded Robbins family of pathology references, Robbins Essential Pathology is a concise resource that covers the core knowledge needed for coursework and exams in an integrated, multimedia format designed for today's students. Ideal for use with an integrated medical curriculum, this easy-to-study multimedia package provides reliable Robbins content in a concentrated, highly efficient format, now fully integrated with interactive digital resources (cases, MCQs, images). Efficient, effective, and up to date, this new Robbins learning resource delivers the essential information you need to obtain a strong scientific foundation in pathology. - The most concise Robbins text available, providing high-quality content and a case-based approach in a focused, multimedia learning package for coursework and exam preparation. - Focuses on the core knowledge of disease mechanisms and essential clinical aspects that medical students need to know. - Features more than 500 images and tables that illustrate key disorders and concepts.

Stroke Genetics

Stroke Genetics
Author: Hugh S. Markus
Publisher:
Total Pages: 362
Release: 2003
Genre: Medical
ISBN: 0198515863

Stroke is a major cause of death and the major cause of adult neurological disability in most of the world. Despite its importance on a population basis, research into the genetics of stroke has lagged behind that of many other disorders. However, the situation is now changing. An increasing number of single gene disorders causing stroke are being described, and there is growing evidence that polygenic factors are important in the risk of apparently "sporadic" stroke. Stroke Genetics provides an up-to-date review of the area, suitable for clinicians treating stroke patients, and both clinical and non-clinical researchers in the field of cerebrovascular disease. The full range of monogenic stroke disorders causing cerebrovascular disease, including ischaemic stroke, intracerebral haemorrhage, aneurysms and arteriovenous malformations, are covered. For each, clinical features, diagnosis, and genetics are described. Increasing evidence suggest that genetic factors are also important for the much more common multifactorial stroke; this evidence is reviewed along with the results of genetic studies in this area. Optimal and novel strategies for investigating multifactorial stroke, including the use of intermediate phenotypes such as intima-media thickness and MRI detected small vessel disease are reviewed. The book concludes by describing a practical approach to investigating patients with stroke for underlying genetic disorders. Also included is a list of useful websites.

Brain Disorders in Critical Illness

Brain Disorders in Critical Illness
Author: Robert D. Stevens
Publisher: Cambridge University Press
Total Pages: 457
Release: 2013-09-19
Genre: Medical
ISBN: 1107434424

Brain dysfunction is a major clinical problem in intensive care, with potentially debilitating long-term consequences for post-ICU patients of any age. The resulting extended length of stay in the ICU and post-discharge cognitive dysfunction are now recognized as major healthcare burdens. This comprehensive clinical text provides intensivists and neurologists with a practical review of the pathophysiology of brain dysfunction and a thorough account of the diagnostic and therapeutic options available. Initial sections review the epidemiology, outcomes, relevant behavioral neurology and biological mechanisms of brain dysfunction. Subsequent sections evaluate the available diagnostic options and preventative and therapeutic interventions, with a final section on clinical encephalopathy syndromes encountered in the ICU. Each chapter is rich in illustrations, with an executive summary and a helpful glossary of terms. Brain Disorders in Critical Illness is a seminal reference for all physicians and neuroscientists interested in the care and outcome of severely ill patients.