The Routledge Handbook of Human Research Ethics and Integrity in Australia highlights why it is important to look at the subject of human research ethics and integrity within the Australian context, and what the Australian perspective can offer to all researchers in the social sciences and humanities globally. Australia has one of the world’s most rigorous ethics governance frameworks. This edited collection comprises 35 chapters, compiled with the aim of presenting human research ethics and integrity in a way that can be readily understood and applied by undergraduate and postgraduate students, early career and seasoned researchers, Human Research Ethics Committee members, and those who work in the administration of human research ethics. Chapters that focus on research ethics with Aboriginal and Torres Strait Islander people are likely to be of great interest to an international audience interested in Indigenous research ethics more broadly. This collection will act as a prism through which ethical ‘first principles’ can be seen afresh from the vista of contemporary Australian research ethics frameworks. The issues raised in this collection are likely to resonate beyond the Australian context and will speak to researchers and educators in a variety of settings who find themselves grappling with thorny ethical issues ranging from the rapid evolution of data security and privacy concerns to research about cultural heritage and ethical approaches to Indigenous cultural and intellectual property.