In Vivo Nmr Spectroscopy
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| Author | : Robin A. de Graaf |
| Publisher | : John Wiley & Sons |
| Total Pages | : 584 |
| Release | : 2019-03-11 |
| Genre | : Science |
| ISBN | : 1119382548 |
Presents basic concepts, experimental methodology and data acquisition, and processing standards of in vivo NMR spectroscopy This book covers, in detail, the technical and biophysical aspects of in vivo NMR techniques and includes novel developments in the field such as hyperpolarized NMR, dynamic 13C NMR, automated shimming, and parallel acquisitions. Most of the techniques are described from an educational point of view, yet it still retains the practical aspects appreciated by experimental NMR spectroscopists. In addition, each chapter concludes with a number of exercises designed to review, and often extend, the presented NMR principles and techniques. The third edition of In Vivo NMR Spectroscopy: Principles and Techniques has been updated to include experimental detail on the developing area of hyperpolarization; a description of the semi-LASER sequence, which is now a method of choice; updated chemical shift data, including the addition of 31P data; a troubleshooting section on common problems related to shimming, water suppression, and quantification; recent developments in data acquisition and processing standards; and MatLab scripts on the accompanying website for helping readers calculate radiofrequency pulses. Provide an educational explanation and overview of in vivo NMR, while maintaining the practical aspects appreciated by experimental NMR spectroscopists Features more experimental methodology than the previous edition End-of-chapter exercises that help drive home the principles and techniques and offer a more in-depth exploration of quantitative MR equations Designed to be used in conjunction with a teaching course on the subject In Vivo NMR Spectroscopy: Principles and Techniques, 3rd Edition is aimed at all those involved in fundamental and/or diagnostic in vivo NMR, ranging from people working in dedicated in vivo NMR institutes, to radiologists in hospitals, researchers in high-resolution NMR and MRI, and in areas such as neurology, physiology, chemistry, and medical biology.
| Author | : Robin A. de Graaf |
| Publisher | : John Wiley & Sons |
| Total Pages | : 563 |
| Release | : 2013-03-21 |
| Genre | : Science |
| ISBN | : 1118681304 |
This is the second edition of a unique book in the field of in vivo NMR covering in detail the technical and biophysical aspects of the technique. The contents of the book are appropriate to both beginners and experienced users of in vivo NMR spectroscopy. The new edition is focussed on bringing the reader practical insights and advice, but is also geared towards use as a study aid and in NMR courses. Recent advances in NMR spectroscopy, like high field NMR, hyperpolarized NMR and new localization and editing techniques have been included. An extensive and updated treatment of radiofrequency pulses is given, together with several tables and recipes for their generation. Solutions to the exercises within this text can be found here
| Author | : Paul A. Bottomley |
| Publisher | : John Wiley & Sons |
| Total Pages | : 1231 |
| Release | : 2016-10-19 |
| Genre | : Medical |
| ISBN | : 1118997697 |
This handbook covers the entire field of magnetic resonance spectroscopy (MRS), a unique method that allows the non-invasive identification, quantification and spatial mapping of metabolites in living organisms–including animal models and patients. Comprised of three parts: Methodology covers basic MRS theory, methodology for acquiring, quantifying spectra, and spatially localizing spectra, and equipment essentials, as well as vital ancillary issues such as motion suppression and physiological monitoring. Applications focuses on MRS applications, both in animal models of disease and in human studies of normal physiology and disease, including cancer, neurological disease, cardiac and muscle metabolism, and obesity. Reference includes useful appendices and look up tables of relative MRS signal-to-noise ratios, typical tissue concentrations, structures of common metabolites, and useful formulae. About eMagRes Handbooks eMagRes (formerly the Encyclopedia of Magnetic Resonance) publishes a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of eMagRes articles. In consultation with the eMagRes Editorial Board, the eMagRes Handbooks are coherently planned in advance by specially-selected Editors, and new articles are written to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this handbook and the complete content of eMagRes at your fingertips! Visit the eMagRes Homepage
| Author | : Joseph B. Lambert |
| Publisher | : John Wiley & Sons |
| Total Pages | : 485 |
| Release | : 2019-01-04 |
| Genre | : Science |
| ISBN | : 1119295238 |
Combines clear and concise discussions of key NMR concepts with succinct and illustrative examples Designed to cover a full course in Nuclear Magnetic Resonance (NMR) Spectroscopy, this text offers complete coverage of classic (one-dimensional) NMR as well as up-to-date coverage of two-dimensional NMR and other modern methods. It contains practical advice, theory, illustrated applications, and classroom-tested problems; looks at such important ideas as relaxation, NOEs, phase cycling, and processing parameters; and provides brief, yet fully comprehensible, examples. It also uniquely lists all of the general parameters for many experiments including mixing times, number of scans, relaxation times, and more. Nuclear Magnetic Resonance Spectroscopy: An Introduction to Principles, Applications, and Experimental Methods, 2nd Edition begins by introducing readers to NMR spectroscopy - an analytical technique used in modern chemistry, biochemistry, and biology that allows identification and characterization of organic, and some inorganic, compounds. It offers chapters covering: Experimental Methods; The Chemical Shift; The Coupling Constant; Further Topics in One-Dimensional NMR Spectroscopy; Two-Dimensional NMR Spectroscopy; Advanced Experimental Methods; and Structural Elucidation. Features classical analysis of chemical shifts and coupling constants for both protons and other nuclei, as well as modern multi‐pulse and multi-dimensional methods Contains experimental procedures and practical advice relative to the execution of NMR experiments Includes a chapter-long, worked-out problem that illustrates the application of nearly all current methods Offers appendices containing the theoretical basis of NMR, including the most modern approach that uses product operators and coherence-level diagrams By offering a balance between volumes aimed at NMR specialists and the structure-determination-only books that focus on synthetic organic chemists, Nuclear Magnetic Resonance Spectroscopy: An Introduction to Principles, Applications, and Experimental Methods, 2nd Edition is an excellent text for students and post-graduate students working in analytical and bio-sciences, as well as scientists who use NMR spectroscopy as a primary tool in their work.
| Author | : Karl H. Hausser |
| Publisher | : Springer |
| Total Pages | : 0 |
| Release | : 2012-02-24 |
| Genre | : Science |
| ISBN | : 9783642761065 |
0 e From the reviews of the German edition: "NMR: readable yet professional... Through this book the reader with a scientific background becomes familiar with all important NMR phenomena, methods and conceptions... The great amount of carefully drawn figures and skillfully selected biologically relevant spectra and figures are an decisive bridge to the ... aim, to convey the NMR basics without mathematics. Besides biologists and physicians the book can be highly recommended to physicists and chemists..." #Nachrichten a. d. Chemie, Technik u. Laboratorien#1 "An extraordinary NMR textbook ... The authors succeeded in presenting the subject vividly. This book is clearly set out and easy to follow at a glance, and its numerous figures are extremely well done." #Labo#2
| Author | : Norbert W. Lutz |
| Publisher | : Cambridge University Press |
| Total Pages | : 641 |
| Release | : 2013-01-21 |
| Genre | : Medical |
| ISBN | : 0521765900 |
Metabolomics, the global characterisation of the small molecule complement involved in metabolism, has evolved into a powerful suite of approaches for understanding the global physiological and pathological processes occurring in biological organisms. The diversity of metabolites, the wide range of metabolic pathways and their divergent biological contexts require a range of methodological strategies and techniques. Methodologies for Metabolomics provides a comprehensive description of the newest methodological approaches in metabolomic research. The most important technologies used to identify and quantify metabolites, including nuclear magnetic resonance and mass spectrometry, are highlighted. The integration of these techniques with classical biological methods is also addressed. Furthermore, the book presents statistical and chemometric methods for evaluation of the resultant data. The broad spectrum of topics includes a vast variety of organisms, samples and diseases, ranging from in vivo metabolomics in humans and animals to in vitro analysis of tissue samples, cultured cells and biofluids.
| Author | : Donald W. McRobbie |
| Publisher | : Cambridge University Press |
| Total Pages | : 380 |
| Release | : 2003 |
| Genre | : Medical |
| ISBN | : 9780521523196 |
Presents the basics of MR practice and theory as the practitioner first meets them.
| Author | : Roger S. Macomber |
| Publisher | : John Wiley & Sons |
| Total Pages | : 406 |
| Release | : 1997-12-23 |
| Genre | : Science |
| ISBN | : 0471157368 |
Clear, accessible coverage of modern NMR spectroscopy-for students and professionals in many fields of science Nuclear magnetic resonance (NMR) spectroscopy has made quantum leaps in the last decade, becoming a staple tool in such divergent fields as chemistry, physics, materials science, biology, and medicine. That is why it is essential that scientists working in these areas be fully conversant with current NMR theory and practice. This down-to-basics text offers a comprehensive, up-to-date treatment of the fundamentals of NMR spectroscopy. Using a straightforward approach that develops all concepts from a rudimentary level without using heavy mathematics, it gives readers the knowledge they need to solve any molecular structure problem from a complete set of NMR data. Topics are illustrated throughout with hundreds of figures and actual spectra. Chapter-end summaries and review problems with answers are included to help reinforce and test understanding of key material. From NMR studies of biologically important molecules to magnetic resonance imaging, this book serves as an excellent all-around primer on NMR spectroscopic analysis.
| Author | : Lu-Yun Lian |
| Publisher | : John Wiley & Sons |
| Total Pages | : 384 |
| Release | : 2011-08-08 |
| Genre | : Science |
| ISBN | : 0470721936 |
Nuclear Magnetic Resonance (NMR) spectroscopy, a physical phenomenon based upon the magnetic properties of certain atomic nuclei, has found a wide range of applications in life sciences over recent decades. This up-to-date volume covers NMR techniques and their application to proteins, with a focus on practical details. Providing newcomers to NMR with practical guidance to carry out successful experiments with proteins and analyze the resulting spectra, those familiar with the chemical applications of NMR will also find it useful in understanding the special requirements of protein NMR.
| Author | : Jacob Valk |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 734 |
| Release | : 2013-04-17 |
| Genre | : Medical |
| ISBN | : 366202568X |
Magnetic resonance imaging (MRI) is now considered the imaging modality of choice for the majority of disorders affecting the central nervous system. This is particularly true for gray and white matter disorders, thanks to the superb soft tis sue contrast in MRI which allows gray matter, unmyelinated, and myelinated white matter to be distinguished and their respective disorders identified. The pre sent book is devoted to the disorders of myelin and myelination. A growing amount of detailed in vivo information about myelin, myelination, and myelin dis orders has been derived both from MRI and from MR spectroscopy (MRS). This prompted us to review the clinical, laboratory, biochemical, and pathological data on this subject in order to integrate all available information and to provide im proved insights into normal and disordered myelin and myelination. We will show how the synthesis of all available information contributes to the interpretation of MR images. After a brief historical review about the increasing knowledge on myelin and my elin disorders, we propose a new classification of myelin disorders based on the subcellular localization of the enzymatic defects as far as the inborn errors of me tabolism are concerned. This classification serves as a guide throughout the book. All items of the classification will be discussed and, whenever relevant and possi ble, be illustrated by MR images.
