Improving Metabolic Engineering And Characterization Of Clostridium Thermocellum For Improved Cellulosic Ethanol Production
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| Author | : John Kadla |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 238 |
| Release | : 2013-08-29 |
| Genre | : Science |
| ISBN | : 9535111728 |
Cellulose is only one of the components of biomass, although being the most abundant. To make useful chemicals or materials from cellulose requires as the first step the separation of cellulose from biomass. Various issues of cellulose extraction and its conversion are discussed in the chapters of this book on cellulose, the third and last one of a series of books on cellulose. This conversion of cellulose is an integral part of the biorefinery concept, an effort to derive optimum value from all biomass components, and as such compulsory reading for students and researchers in this area.
| Author | : Christoph Wittmann |
| Publisher | : John Wiley & Sons |
| Total Pages | : 789 |
| Release | : 2017-04-10 |
| Genre | : Science |
| ISBN | : 352734179X |
The latest volume in the Advanced Biotechnology series provides an overview of the main production hosts and platform organisms used today as well as promising future cell factories in a two volume book. Alongside describing tools for genetic and metabolic engineering for strain improvement, the authors also impart topical information on computational tools, safety aspects and industrial-scale production. Following an introduction to general concepts, historical developments and future technologies, the text goes on to cover multi-purpose bacterial cell factories, including those organisms that exploit anaerobic biosynthetic power. Further chapters deal with microbes used for the production of high-value natural compounds and those obtained from alternative raw material sources, concluding with eukaryotic workhorses.
| Author | : Sang Yup Lee |
| Publisher | : John Wiley & Sons |
| Total Pages | : 1075 |
| Release | : 2021-06-02 |
| Genre | : Science |
| ISBN | : 352782345X |
Learn more about foundational and advanced topics in metabolic engineering in this comprehensive resource edited by leaders in the field Metabolic Engineering: Concepts and Applications delivers a one-stop resource for readers seeking a complete description of the concepts, models, and applications of metabolic engineering. This guide offers practical insights into the metabolic engineering of major cell lines, including E. Coli, Bacillus and Yarrowia Lipolytica, and organisms, including human, animal, and plant). The distinguished editors also offer readers resources on microbiome engineering and the use of metabolic engineering in bioremediation. Written in two parts, Metabolic Engineering begins with the essential models and strategies of the field, like Flux Balance Analysis, Quantitative Flux Analysis, and Proteome Constrained Models. It also provides an overview of topics like Pathway Design, Metabolomics, and Genome Editing of Bacteria and Eukarya. The second part contains insightful descriptions of the practical applications of metabolic engineering, including specific examples that shed light on the topics within. In addition to subjects like the metabolic engineering of animals, humans, and plants, you’ll learn more about: Metabolic engineering concepts and a historical perspective on their development The different modes of analysis, including flux balance analysis and quantitative flux analysis An illuminating and complete discussion of the thermodynamics of metabolic pathways The Genome architecture of E. coli, as well as genome editing of both bacteria and eukarya An in-depth treatment of the application of metabolic engineering techniques to organisms including corynebacterial, bacillus, and pseudomonas, and more Perfect for students of biotechnology, bioengineers, and biotechnologists, Metabolic Engineering: Concepts and Applications also has a place on the bookshelves of research institutes, biotechnological institutes and industry labs, and university libraries. It's comprehensive treatment of all relevant metabolic engineering concepts, models, and applications will be of use to practicing biotechnologists and bioengineers who wish to solidify their understanding of the field.
| Author | : Ayerim Y. Hernández Almanza |
| Publisher | : CRC Press |
| Total Pages | : 542 |
| Release | : 2022-07-07 |
| Genre | : Science |
| ISBN | : 1000565130 |
This new book, Bioethanol: Biochemistry and Biotechnological Advances, presents some insightful perspectives and important advances in the bioethanol industry. The volume goes into detail on the biochemical and physiological parameters carried out by the main bioethanol-producing microorganisms as well as the discusses the potential applications that bioproducts can have and the advantages they generate. The chapter authors discuss a variety of issues, including the physiology of ethanol production by yeasts, by Zymomonas mobilis, and by Clostridium thermocellum. Other sources of biofuel, such as sweet sorghum, Agave americana L. leaves waste, and fungi are included as well. Chapters also discuss the genetic regulation and genetic engineering of principal microorganisms and then go on to address ways to increase ethanol tolerance in industrially important ethanol fermenting organisms, methods for developing sustainable fermentable substrates, and new strategies for ethanol purification. Chapters explore the design and engineering requirements for bioreactors, bioelectrosynthesis of ethanol via bioelectrochemical systems, and more. The book will be a valuable resource for faculty and students in this area as well as for scientists, researchers, and managers in the biofuel industry in the area of biofuel production, fermentation process, environmental engineering and all other related scientific areas.
| Author | : Arindam Kuila |
| Publisher | : Elsevier |
| Total Pages | : 256 |
| Release | : 2020-02-19 |
| Genre | : Technology & Engineering |
| ISBN | : 0128179546 |
Genetic and Metabolic Engineering for Improved Biofuel Production from Lignocellulosic Biomass describes the different aspects of biofuel production from lignocellulosic biomass. Each chapter presents different technological approaches for cost effective liquid biofuel production from agroresidues/biomass. Two chapters cover future direction and the possibilities of biomass-based biofuel production at the industrial level. The book provides a genetic and metabolic engineering approach for improved cellulase production and the potential of strains that can ferment both pentose and hexose sugars. The book also gives direction on how to overcome challenges for the further advancement of lignocellulosic biomass-based biofuel production. - Covers genetic engineering approaches for higher cellulase production from fungi - Includes genetic and metabolic engineering approaches for development of potential pentose and hexose fermenting strain which can tolerate high ethanol and toxic phenolic compounds - Describe different bioreactors used in different steps of biomass-based biofuel production - Outlines future prospects and potential of biofuel production from lignocellulosic biomass
| Author | : Peter Duerre |
| Publisher | : CRC Press |
| Total Pages | : 1451 |
| Release | : 2005-03-29 |
| Genre | : Medical |
| ISBN | : 113550198X |
Clostridia is one of the largest bacterial genera with an enormous potential for biotechnical and medical applications. Despite growing scientific, medical, and industrial interest, information on basic methods, biochemical fundamentals, clinical practice, industrial applications, and novel developments remains scattered in a variety of research ar
| Author | : Pengcheng Fu |
| Publisher | : John Wiley & Sons |
| Total Pages | : 672 |
| Release | : 2009-08-13 |
| Genre | : Technology & Engineering |
| ISBN | : 9780470437971 |
The genomic revolution has opened up systematic investigations and engineering designs for various life forms. Systems biology and synthetic biology are emerging as two complementary approaches, which embody the breakthrough in biology and invite application of engineering principles. Systems Biology and Synthetic Biology emphasizes the similarity between biology and engineering at the system level, which is important for applying systems and engineering theories to biology problems. This book demonstrates to students, researchers, and industry that systems biology relies on synthetic biology technologies to study biological systems, while synthetic biology depends on knowledge obtained from systems biology approaches.
| Author | : Geoffrey M. Gadd |
| Publisher | : Academic Press |
| Total Pages | : 202 |
| Release | : 2020-09-16 |
| Genre | : Science |
| ISBN | : 0128207108 |
Advances in Applied Microbiology, Volume 113, continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topic, with this release focusing on Gaps in the Assortment of Rapid Assays for Microorganisms of Interest to the Dairy Industry, Metal reduction and corrosion by bacterial biofilms, The microbiology of red brines, Clostridium thermocellum: a microbial platform for high-value chemical production from lignocellulose, and The zincophore system in pathogenic yeasts. - Contains contributions from leading authorities in the field - Informs and updates on all the latest developments in the field of microbiology - Includes discussions on the role of specific molecules in pathogen life stages, interactions, and much more
| Author | : Mohammed Kuddus |
| Publisher | : Academic Press |
| Total Pages | : 340 |
| Release | : 2021-08-20 |
| Genre | : Science |
| ISBN | : 0128231025 |
Microbial Extremozymes: Novel Sources and Industrial Applications is a unique resource of practical research information on the latest novel sources and technologies regarding extremozymes in bioremediation, waste management, valorization of industrial by-products, biotransformation of natural polymers, nutrition, food safety and diagnosis of disease. The book's broad knowledge and varying applications are useful to the food industry, dairy industry, fruit and vegetable processing, and baking and beverages industries, as well as the pharmaceutical and biomedical industries. This is a concise, all-encompassing resource for a range of scientists needing knowledge of extremozymes to enhance and research. Furthermore, it provides an updated knowledge of microbial enzymes isolated from extreme environments (temperatures, etc.) and their biotechnological applications. It will be useful to researchers, scientists and students in enzyme research. In addition, users from the dairy and baking industries will benefit from the presented content. - Explores recent scientific research on extremophiles and extremozymes technologies that help innovate novel ideas - Provides innovative technologies for enzyme production from extremophilic microbes - Includes cutting-edge research for applications in various industries where extreme temperature conditions exist - Presents novel microorganisms and their enzymes from extreme environments (Thermophilic, Psychrophilic, Acidophilic, Alkaliphilic, Anaerobic, Halophilic, Barophilic, Metallotolerant, Radioresistant, etc.)
| Author | : Guillermo Gosset |
| Publisher | : Springer |
| Total Pages | : 203 |
| Release | : 2017-01-26 |
| Genre | : Medical |
| ISBN | : 3319517295 |
This book reviews state of the art regarding strategies for generating and improving microbial strains designed for utilizing renewable raw materials. It discusses methods for genetically engineering of thermophilic bacteria, Saccharomyces cerevisiae, Escherichia coli and Zymomonas mobilis, as well as approaches for obtaining useful products from these renewable raw materials based on biotechnological processes using microbes to chemically transform them. However, the efficient transformation of lignocellulosic biomass or glycerol to useful products represents a major challenge: Biomass has to be treated physically and chemically to release a mixture of sugars that potentially can be employed by the microbial production strains. These hydrolytic treatments result in diverse toxic compounds being generated and released, that negatively impact strain performance. Furthermore, most of the commonly used industrial microbes do not have the natural capacity to efficiently utilize and transform the generated sugar mixtures or glycerol. The microbial species reviewed in this book possess particular advantages as production strains and are currently employed for the synthesis of numerous biofuels and chemicals. The book reviews the general and strain-specific genetic engineering strategies for the improvement of sugar mixtures and glycerol catabolism. The issue of lignocellulosic hydrolysate toxicity is addressed in several chapters, where genetic engineering and adaptive laboratory evolution strategies are reviewed and discussed. The objective of this book is to provide the current knowledge regarding strategies for the generation and improvement of microbial strains designed for the transformation of renewable raw materials into useful products. This book aims to become a reference for researchers and students working in this field.
