Immunology of ENT Disorders

Immunology of ENT Disorders
Author: Glenis K. Scadding
Publisher: Springer Science & Business Media
Total Pages: 236
Release: 2012-12-06
Genre: Medical
ISBN: 9401114366

Until recently, the contribution of immunological knowledge to the under standingand management ofENTdisorders was slight, being largely confined to the appreciation that many rhinitic patients were allergic. Happily, this situation is rapidly changing: the immunological basis of many disorders of the ears, nose and throat is becoming recognized and the mechanisms of the reactions involved are being elucidated. From this, rational therapy should evolve. This book aims to highlight some of the areas in which immunological mechanisms are involved in otorhinolaryngology. It is written by experts in their respective fields of immunology and allergy, otology, rhinology and pathology. It opens with an overview ofthe pathways ofthe immune response and the cells and molecules involved, leading to an appreciation of the normal defence mechanisms of the upper respiratory tract and possible areas offailure. There is then a chapter on HIV infection and how this may present to otorhinolaryngologists. The normal function of the tonsil and the immunological effects oftonsillectomy are then considered. The varying roles of fungi in ENT disorders ranging from commensal through allergen to invasive organisms is assessed by Professor R. J. Hay. Perhaps the most obvious immunological contribution to management thus far lies in the immunocytochemical diagnosis of pathological conditions of the ears, nose and throat and this is covered in a chapter by Professor Leslie Michaels.

Interleukins in Cancer Biology

Interleukins in Cancer Biology
Author: Arseniy Yuzhalin
Publisher: Academic Press
Total Pages: 361
Release: 2014-06-27
Genre: Medical
ISBN: 0128013338

Interleukins in Cancer Biology responds to the growing need for credible and up-to-date information about the impact of interleukins on occurrence, development and progression of cancer. It provides reliable information about all known interleukins (38), describes recent discoveries in the field, and moreover, suggests further directions of research on the most promising aspects of this topic. The structure and presentation of the work is very understandable and clear with attention to detail maintained throughout. There are multiple illustrations throughout to help in comprehending and remembering the most important facts. . - Summarizes and discusses existing facts on the impact of all known interleukins in occurrence, development, and progression of cancer - Categorizes and clarifies all interleukins based on their role in cancer - Contains comprehensive and exhaustive information on each molecule

Evidence-Based Clinical Practice in Otolaryngology

Evidence-Based Clinical Practice in Otolaryngology
Author: Luke Rudmik
Publisher: Elsevier Health Sciences
Total Pages: 203
Release: 2018-01-20
Genre: Medical
ISBN: 0323544614

Get a quick, expert overview of the many key facets of today's otolaryngology practice with this concise, practical resource. Dr. Luke Rudmik and a leading team of experts in the field address high-interest clinical topics in this fast-changing field. - Presents an evidence-based, clinical approach to leading topics in otolaryngology. - Covers key topics such as management of vertigo; management of adult sensorineural hearing loss; reflux in sinusitis; balloon catheter dilation in rhinology; epistaxis; functional rhinoplasty; sublingual immunotherapy for allergic rhinitis; pediatric obstructive sleep apnea; pediatric tonsillectomy; evaluation and management of unilateral vocal fold paralysis; management of hoarseness; endoscopic skull base resection for malignancy; management of glottic cancer; management of well-differentiated thyroid cancer; and management of the clinical node-negative neck in early stage oral cavity squamous cell carcinoma. - Consolidates today's available information and experience in this challenging area into one convenient resource.

Immunological Aspects of Gastroenterology

Immunological Aspects of Gastroenterology
Author: Y.R. Mahida
Publisher: Springer Science & Business Media
Total Pages: 359
Release: 2012-12-06
Genre: Medical
ISBN: 940100790X

Diseases of the gastrointestinal tract are common. There is increasing appreciation of the importance of the immune system in the pathogenesis of a number of these diseases. This book covers basic aspects of innate and adaptive immunity in the gastrointestinal tract, oral tolerance, and cellular and molecular mechanisms of acute and chronic inflammation. Specific disease covered include bacterial infections, human immunodeficiency virus (HIV) infection, coeliac disease, and inflammatory bowel disease. Other topics include mucosal immunisation and intestinal transplantation immunology. The readership of this book includes clinicians, scientists, and students interested in the gastrointestinal tract.

Cancer Immunology

Cancer Immunology
Author: R.A. Robins
Publisher: Springer Science & Business Media
Total Pages: 268
Release: 2013-03-14
Genre: Medical
ISBN: 9401709637

This publication provides a comprehensive account of the known groups of human tumour antigens, and the immune effector cells involved in tumour rejection. Chapters dealing with all the major groups of human tumour antigens are included, covering differentiation antigens, testes-associated antigens, CEA, mucin, viral antigens, anti-idiotypic antibodies as antigens, and fusion proteins. The role of heat shock proteins as mediators of tumour immunity is discussed and consideration is given to the immune mechanisms which mediate tumour rejection in both human and animal systems. The application of antibody targeting to identify cancers, and the mechanisms by which tumours evade immune detection and/or destruction is covered in detail. Although the focus of this publication is experimental, as with other recent publications progress in clinical immunotherapy is included in some detail, to provide postgraduate and post-doctoral scientists with in-depth reviews of the field.

Endocrine Autoimmunity and Associated Conditions

Endocrine Autoimmunity and Associated Conditions
Author: Anthony P. Weetman
Publisher: Springer Science & Business Media
Total Pages: 324
Release: 1998
Genre: Medical
ISBN: 9780792350422

Autoimmunity is the most common cause of endocrine disorders. This volume provides an up-to-date summary of advances in this field. In addition, it describes developments in our understanding of conditions such as vitiligo and pernicious anaemia which are frequently associated with autoimmune endocrinopathies. There is a detailed review of animal models of endocrine disease which have contributed greatly to current knowledge. Furthermore, the aetiology, pathogenesis and treatment of the clinical disorders are discussed in depth. The book should be of interest to anyone working in the areas of endocrinology and immunology.

Therapeutic Immunosuppression

Therapeutic Immunosuppression
Author: Angus W. Thomson
Publisher: Springer Science & Business Media
Total Pages: 534
Release: 2001
Genre: Medical
ISBN: 9780792368892

This work has broad applications in clinical medicine, ranging from prevention and treatment of organ and bone marrow transplant rejection, management of various autoimmune disorders (for example, rheumatoid arthritis), skin disease and asthma. Whereas traditionally only a small repertoire of immunosuppressive agents was available for clinical use, recent discoveries have significantly increased the number of approved agents, resulting in numerous trials to further evaluate their potential. There is also considerable interest in the potential of cell-based therapies (particularly hematopoietic stem and dendritic cell therapy) of allo- and autoimmunity. Important recent advances in the immunotherapy of allergic diseases are also covered in this book. This volume is intended both for practising physicians and surgeons and for biomedical scientists at the graduate/postdoctoral levels, and is designed to provide the theory behind these various approaches to immunosuppression, and to provide state-of-the-art reviews of current developments in each area.

Oxford Handbook of ENT and Head and Neck Surgery

Oxford Handbook of ENT and Head and Neck Surgery
Author: Rogan Corbridge
Publisher: OUP Oxford
Total Pages: 243
Release: 2009-12-24
Genre: Medical
ISBN: 0191039640

This second edition of a best-selling Oxford Medical Handbook provides a comprehensive guide to the practice of ENT and head and neck surgery in a concise, practical, and easily accessible format. For use on the ward or for revision purposes, this new edition is organised anatomically and each section provides a summary of the essential approach to a specific presenting complaint. Quick access chapters are included detailing emergency conditions and their acute management. This new edition includes expanded sections on anatomy, paediatrics, drugs, practical and surgical procedures, and emergencies. There are new chapters covering ENT manifestations in HIV/AIDS and sleep disorders. Still the only pocket-sized reference of ENT available, this handbook is unique in offering diagnostic flowcharts which guide readers based on specific sets of symptoms. Patient-centred and practical, this book represents a more accurate experience for those typically faced with ENT and head and neck surgery in clinical practice.

Diseases of the Sinuses

Diseases of the Sinuses
Author: Christopher C. Chang
Publisher: Springer
Total Pages: 600
Release: 2014-06-06
Genre: Medical
ISBN: 1493902652

Diseases of the Sinuses: A Comprehensive Textbook of Diagnosis and Treatment, 2nd Edition, offers the definitive source of information about the basic science of the sinuses and the clinical approach to sinusitis. Since the widely praised publication of the first edition, understanding of sinus disease has changed dramatically, mainly as a result of recent developments and new discoveries in the field of immunology. This updated and expanded edition is divided into sections addressing, separately, the pathogenesis, clinical presentation, medical and surgical management of acute and chronic rhinosinusitis. Special entities such as autoimmune-related sinusitis, allergy and sinusitis, and aspirin-exacerbated respiratory disease are discussed in separate chapters. The role of immunodeficiency is also addressed. The management section has been fully updated to incorporate new medical modalities and surgical procedures. Developed by a distinguished group of international experts who share their expertise and insights from years of collective experience in treating sinus diseases, the book will appeal to anyone who has an interest in sinus disease, including both physicians and allied health professionals. Internists, pediatricians, allergists, otolaryngologists and infectious disease specialists will find the book to be an invaluable, comprehensive reference. Physician assistants and nurse practitioners who work with specialists who treat sinus disease will also benefit from the book.