Immunohistochemistry And In Situ Hybridization Of Human Carcinomas Molecular Genetics Liver And Pancreatic Carcinomas
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Handbook of Immunohistochemistry and in situ Hybridization of Human Carcinomas
| Author | : M. A. Hayat |
| Publisher | : Elsevier |
| Total Pages | : 261 |
| Release | : 2005-09-21 |
| Genre | : Science |
| ISBN | : 0080456251 |
Immunohistochemistry is the use of specific antibodies to stain particular molecular species in situ. This technique has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system, and has the potential to improve diagnosis, prognosis and therapeutic options of cancer. This book discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method. The topics of region-specific gene expression, its role in cancer development and the techniques that assist in the understanding of the molecular basis of disease are relevant and necessary in science today.* The only book available that translates molecular genetics into cancer diagnosis * The results of each Immunohistochemical and in situ hybridization method are presented in the form of color illustrations * Methods discussed were either developed or refined by expert contributors in their own laboratories
Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas
| Author | : M. A. Hayat |
| Publisher | : Academic Press |
| Total Pages | : 536 |
| Release | : 2005-01-12 |
| Genre | : Medical |
| ISBN | : |
Discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. The series provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method. The topics of region-specific gene expression, its role in cancer development and the techniques that assist in the understanding of the molecular basis of disease are relevant and necessary in science today, ensuring a wide audience for this book. Translates molecular genetics into cancer diagnosis and the results of each Immunohistochemical and in situ hybridization method are presented in the form of color illustrations.
The Papanicolaou Society of Cytopathology System for Reporting Pancreaticobiliary Cytology
| Author | : Martha Bishop Pitman |
| Publisher | : Springer |
| Total Pages | : 107 |
| Release | : 2015-05-30 |
| Genre | : Medical |
| ISBN | : 3319165895 |
This text and the terminology developed by the Papanicolaou Society of Cytopathology (P.S.C.) represents an important advance in the field of pancreaticobiliary cytopathology. This textbook/atlas is designed to present a comprehensive and state of the art approach to the cytologic diagnosis and reporting of pancreaticobiliary lesions. Chapters address each of the diagnostic categories defined by the P.S.C. The definition of each category along with the clinical pathologic entities contained within the category are discussed along with specific cytologic criteria for inclusion of a cytologic specimen within the category. Each chapter is lavishly illustrated demonstrating diagnostic criteria and examples of lesions contained within the category. Additionally, appropriate ancillary testing is discussed and where appropriate illustrated. Each chapter concludes with a discussion of appropriate management as well as estimates of malignancy risk for the category. The Papanicolaou Society of Cytopathology System for Reporting Pancreaticobiliary Cytology: Definitions, Criteria, Ancillary Testing and Management will provide the reader with a unified approach to diagnosing and reporting interpretations of cytologic specimens obtained from the pancreaticobiliary tract. This text/atlas will serve as a reference guide for pathologists, surgeons, endoscopists and radiologists.
Modern Immunohistochemistry
| Author | : Peiguo Chu |
| Publisher | : Cambridge University Press |
| Total Pages | : 1179 |
| Release | : 2014-02-27 |
| Genre | : Medical |
| ISBN | : 1316184455 |
Since the publication of the first edition of this best-selling book in 2009, the field of immunohistochemistry has advanced significantly. Fully updated to reflect the latest developments in the field, Modern Immunohistochemistry, Second Edition, is a practical guide to all the important diagnostic markers in each organ system. Concise text is supplemented by over 1,100 high-quality colour images and algorithms. The new edition features even more summary tables, highlighting the key points of differential immunophenotypic panels. A new, expanded introduction explains the basic principles of immunohistochemistry, and chapters have been updated to incorporate predictive/prognostic markers and the latest WHO classifications. All chapters are written by the same expert authors, providing a consistent, engaging style throughout and avoiding contradictory advice. An essential text for residents, this is also an extremely valuable resource for practitioners in anatomic pathology wishing to familiarise themselves with diagnostic markers at a quick glance.
Odze and Goldblum Surgical Pathology of the GI Tract, Liver, Biliary Tract and Pancreas
| Author | : Robert D. Odze |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 2356 |
| Release | : 2022-06-21 |
| Genre | : Medical |
| ISBN | : 0323872646 |
Unparalleled in scope and content, Surgical Pathology of the GI Tract, Liver, Biliary Tract and Pancreas provides the most relevant and up-to-date clinical, etiologic, molecular, and therapeutic management information for surgical pathologists in training and in practice. The fully revised 4th Edition of this award-winning title offers a wealth of information in this fast-changing field, including recent advances in molecular biology and immunohistochemistry, in a clearly written, well-structured manner that is easy to read and navigate. This one-stop reference for the entire gastrointestinal system enables you to improve turnaround time when diagnosing a specimen and to clearly report on the prognosis and therapeutic management options to surgical and medical colleagues. Covers the latest developments in molecular technologies and immunohistochemical markers to provide useful diagnostic and prognostic information and inform therapeutic decisions. Provides all the necessary tools to make a comprehensive diagnostic workup, including data from ancillary techniques and molecular findings whenever appropriate. Incorporates more than 3000 high-quality color illustrations to help you recognize and diagnose any tissue sample under the microscope. Reviews next-generation sequencing (NGS) to help identify targetable mutations in gastrointestinal tract tumors and provide more accurate classification and precision therapies. Features extensive tables, graphs, and flowcharts to help you effectively grasp complex topics and streamline your decision-making. Helps you avoid diagnostic errors with practical advice on pitfalls in differential diagnosis. Incorporates the latest WHO guidelines throughout. Winner of the 2015 BMA Medical Book Awards First Prize Award in Pathology.
How Tobacco Smoke Causes Disease
| Author | : United States. Public Health Service. Office of the Surgeon General |
| Publisher | : |
| Total Pages | : 728 |
| Release | : 2010 |
| Genre | : Government publications |
| ISBN | : |
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Molecular Genetic Pathology
| Author | : Liang Cheng |
| Publisher | : Springer |
| Total Pages | : 1136 |
| Release | : 2013-03-05 |
| Genre | : Medical |
| ISBN | : 9781461447993 |
Molecular Genetic Pathology, Second Edition presents up-to-date material containing fundamental information relevant to the clinical practice of molecular genetic pathology. Fully updated in each area and expanded to include identification of new infectious agents (H1N1), new diagnostic biomarkers and biomarkers for targeted cancer therapy. This edition is also expanded to include the many new technologies that have become available in the past few years such as microarray (AmpliChip) and high throughput deep sequencing, which will certainly change the clinical practice of molecular genetic pathology. Part I examines the clinical aspects of molecular biology and technology, genomics. Poharmacogenomics and proteomics, while Part II covers the clinically relevant information of medical genetics, hematology, transfusion medicine, oncology, and forensic pathology. Supplemented with many useful figures and presented in a helpful bullet-point format, Molecular Genetic Pathology, Second Edition provides a unique reference for practicing pathologists, oncologists, internists, and medical genetisists. Furthermore, a book with concise overview of the field and highlights of clinical applications will certainly help those trainees, including pathology residents, genetics residents, molecular pathology fellows, internists, hematology/oncology fellows, and medical technologists in preparing for their board examination/certification.
Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas
| Author | : M. A. Hayat |
| Publisher | : Academic Press |
| Total Pages | : 662 |
| Release | : 2006 |
| Genre | : Medical |
| ISBN | : |
Discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. The series provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method. The topics of region-specific gene expression, its role in cancer development and the techniques that assist in the understanding of the molecular basis of disease are relevant and necessary in science today, ensuring a wide audience for this book. Translates molecular genetics into cancer diagnosis and the results of each Immunohistochemical and in situ hybridization method are presented in the form of color illustrations.
