Immunoelectron Microscopic Studies Using Monoclonal Antibodies Demonstrating The Presence Of An Antigen On The Surface Of Merozoites Of The Rodent Malarial Parasite Plasmodium Yoelii
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| Author | : Irwin W. Sherman |
| Publisher | : Amer Society for Microbiology |
| Total Pages | : 575 |
| Release | : 1998-01 |
| Genre | : Medical |
| ISBN | : 9781555811310 |
Every 30 seconds a death is caused by Malaria. This book brings together recent advances in our understanding of the basic biology, genetics and pathogenesis of malaria, to facilitate the rapid generation of new insights and interventions. Each chapter is written by a leading expert(s), and serves as both a useful introduction to the area and a helpful set of references. Malaria: Parasite Biology, Pathogenesis and Protection is a useful entry point for graduate and medical students, scientists and individuals engaged in a subspecialty of Malaria research, as well as those who are simply interested in getting a grasp on the present status of this ever burgeoning public health problem.
| Author | : R. Killick-Kendrick |
| Publisher | : Elsevier |
| Total Pages | : 435 |
| Release | : 2012-12-02 |
| Genre | : Medical |
| ISBN | : 0323150578 |
Rodent Malaria reviews significant findings concerning malaria parasites of rodents, including their taxonomy, zoogeography, and evolution, along with life cycles and morphology; genetics and biochemistry; and concomitant infections. This volume is organized into eight chapters and begins by sketching out the history of the discovery of rodent as well as aspects of parasitology, immunology, and chemotherapy. These concepts are investigated two decades following Ignace Vincke's major discovery and Meir Yoeli's successful establishment of the method of cyclical transmission of the parasite. The following chapters focus on the taxonomy and systematics of the subgenus Vinckeia, with reference to the concepts of species and subspecies of animals and the degree to which they apply to malaria parasites, in particular to those of rodents. The discussion then shifts to how the rodent malaria parasites provide a unique insight into the subcellular organization of Plasmodium species, the use of rodent malaria as an experimental model to study immunological responses, and infectious agents that interact with malaria parasites. The book concludes with a chapter on malaria chemotherapy, with emphasis on the value of rodent malaria in antimalarial drug screening and the use of antimalarial drugs as biological probes. This book will be of interest to protozoologists and physicians as well as those from other disciplines including biochemistry, immunology, pharmacology, cell biology, and genetics.
| Author | : Masamichi Aikawa |
| Publisher | : |
| Total Pages | : 88 |
| Release | : 1974 |
| Genre | : Medical |
| ISBN | : |
| Author | : Joseph Marr |
| Publisher | : Elsevier |
| Total Pages | : 363 |
| Release | : 1995-09-06 |
| Genre | : Science |
| ISBN | : 0080527884 |
The study of parasitic organisms at the molecular level has yielded fascinating new insights of great medical, social, and economical importance, and has pointed the way for the treatment and prevention of the diseases they cause. Biochemistry and Molecular Biology of Parasites presents an up-to-date account of this modern scientific discipline in a manner that allows and encourages the reader to place the biochemistry and molecular biology of these organisms in their biological context. The chapters are cross-referenced and grouped in an arrangement that provides a fully integrated whole, and permits the reader to create a composite of the biochemical function of these organisms.Individual chapter includes those devoted to metabolism, in both aerobic and anaerobic protozoa; antioxidant mechanisms; parasite surfaces; organelles; invasion mechanisms; and chemotherapy. The helminths are discussed not only from the point of view of their cellular biochemistry and metabolism, but also with respect to both their integrated functions such as neurochemistry, structure and functions of surfaces, and reproduction. Written by expert investigators, this book will be of interest to all experienced researchers, graduate students, and to the newcomer eager to become familiar with the biochemistry and molecular biology of parasites.
| Author | : Percy Cyril Claude Garnham |
| Publisher | : |
| Total Pages | : 1234 |
| Release | : 1966 |
| Genre | : Apicomplexa |
| ISBN | : |
| Author | : Denise L. Doolan |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 606 |
| Release | : 2008-02-02 |
| Genre | : Medical |
| ISBN | : 1592592716 |
The Plasmodium spp. parasite was identified as the causative agent of malaria in 1880, and the mosquito was identified as the vector in 1897. Despite subsequent efforts focused on the epidemiology, cell biology, immunology, molecular biology, and clinical manifestations of malaria and the Plasmodium parasite, there is still no licensed vaccine for the prevention of malaria. Physical barriers (bed nets, window screens) and chemical prevention methods (insecticides and mosquito repellents) intended to interfere with the transmission of the disease are not highly effective, and the profile of resistance of the parasite to chemoprophylactic and chemotherapeutic agents is increasing. The dawn of the new millennium has seen a resurgence of interest in the disease by government and philanthropic organizations, but we are still faced with compl- ities of the parasite, the host, and the vector, and the interactions among them. Malaria Methods and Protocols offers a comprehensive collection of protocols describing conventional and state-of-the-art techniques for the study of malaria, as well as associated theory and potential problems, written by experts in the field. The major themes reflected here include assessing the risk of infection and severity of disease, laboratory models, diagnosis and typing, molecular biology techniques, immunological techniques, cell biology techniques, and field applications.
| Author | : John E. Hyde |
| Publisher | : Taylor & Francis US |
| Total Pages | : 488 |
| Release | : 1993-08-11 |
| Genre | : Medical |
| ISBN | : 9780896032392 |
Experts present methods and protocols essential for understanding parasites at the molecular level. The protocols cover culturing techniques for the major experimental organisms, methods for isolating and processing nucleic acids and proteins, PCR-based protocols for parasite identification, gene isolation and mutation, antibody-based procedures, chromosome and epitope mapping, flow cytometry, RNA sequencing, and parasite transformation.
| Author | : |
| Publisher | : Elsevier |
| Total Pages | : 443 |
| Release | : 2007-03-23 |
| Genre | : Medical |
| ISBN | : 0080471021 |
First published in 1963, Advances in Parasitology contains comprehensive and up-to-date reviews in all areas of interest in contemporary parasitology. This volume is an outline of global environmental and global population data including scripts for predicting disease distributions and evaluating the accuracy of these mapped products. Several application chapters discuss current research topics appropriately addressed at the global scale. Topics such as tick-borne disease and the mapping of geographic and phylogenetic space; implications of global ecozonation and transportation networks on pathogen flow; and the impacts of climate change on vector-borne diseases are covered in this latest volume.* Includes DVD of global environmental and global population data, including scripts for predicting disease distributions and evaluating the accuracy of these mapped products* Valuable source of both technical and epidemiological data in this rapidly growing field* Discusses practical applications of techniques to the study of parasitic and infectious diseases
| Author | : Stephen L. Hoffman |
| Publisher | : Amer Society for Microbiology |
| Total Pages | : 310 |
| Release | : 1996-01 |
| Genre | : Medical |
| ISBN | : 9781555811112 |
Malaria Vaccine Development is an important reference that investigates exciting new strategies in the field. Chapters from the world's leading authorities report major breakthroughs in vaccine design and delivery and discuss the completely new generation of multicomponent vaccines. Immunologists, vaccinologists, parasitologists, and tropical medicine clinicians and researchers will find this volume to be an essential reference.
| Author | : Arch G. Mainous III |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 409 |
| Release | : 2010-02-04 |
| Genre | : Medical |
| ISBN | : 1603272399 |
Recent evidence suggests an increasing rate of antimicrobial resistant pathogens throughout the world. Pathogens like Staphylococcus aureus are showing substantial prevalence of resistance to antibiotics. Thus, we think that given these developments, clinicians would welcome an updated version of this book. A resource indicating appropriate, evidence-based antimicrobial treatment of infectious diseases encountered in both the hospital and outpatient settings would be of significant value to practicing clinicians. The book would focus on the clinical importance of appropriate diagnosis and treatment of infectious diseases particularly in terms of antibiotic-resistance. The resource would be valuable to countless numbers of junior-level practitioners (residents, nurse practitioners, physician-assistants). Moreover, the book could be a resource for generalists as well as infectious disease specialists.
