Hypospadias and Genital Development

Hypospadias and Genital Development
Author: Laurence S. Baskin
Publisher: Springer Science & Business Media
Total Pages: 258
Release: 2012-12-06
Genre: Medical
ISBN: 1441989951

This book focuses on the current basic science research of hypospadias and genital development. Congenital anomalies of the genitalia are the second most common birth abnormality besides congenital heart defects. Genital anomalies come in many varieties with the most common abnormality being hypospadias. The etiology of hypospadias remains unknown and the incidence is doubling in western countries with no definable explanation. It therefore seems especially germane to study this common congenital anomaly with a baseline incidence of 1/125-250 newborn males.

Hypospadias Surgery

Hypospadias Surgery
Author: Ahmed Hadidi
Publisher: Springer Science & Business Media
Total Pages: 372
Release: 2013-11-11
Genre: Medical
ISBN: 3662078414

Acknowledging the fact that hypospadiology has become a true subspecialty, this unique book highlights and explores current philosophy and different principles and techniques of hypospadias repair. It offers an excellent practical guide to all surgeons involved in the management of this common, but troublesome disease. The aim is to help interested surgeons to develop vision, philosophy and talent rather than just enumerate techniques. It is well illustrated with ample colour diagrams and photographs of various operations together with many technical tips. All surgeons in training will benefit by reading this book in preparing for their higher examinations and their surgical training. There is a wide diversity of opinions, and a large number of operations have been described. Here, the team of world class authors present an expert overview on the management of this condition.

An Illustrated Guide to Pediatric Surgery

An Illustrated Guide to Pediatric Surgery
Author: Ahmed H. Al-Salem
Publisher: Springer
Total Pages: 589
Release: 2014-09-24
Genre: Medical
ISBN: 331906665X

Written in a simple point by point style for ease of use, this volume covers all aspects of pediatric surgery with emphasis on important points for diagnosis and management. Each chapter covers a topic with emphasis on the most common conditions in neonatal and general pediatric surgery. The text is well illustrated with clinical, operative, radiological, and histopathological color figures and illustrations. The book also presents some of the rare conditions encountered in pediatric surgery, as well as common pediatric urology conditions. An Illustrated Guide to Pediatric Surgery is a useful reference to pediatric surgeons, specialists, fellows and residents, as well as general surgeons, pediatricians, neonatologists, medical students and interns interested in pediatric surgery.

Ashcraft's Pediatric Surgery E-Book

Ashcraft's Pediatric Surgery E-Book
Author: George W. Holcomb
Publisher: Elsevier Health Sciences
Total Pages: 1191
Release: 2014-01-31
Genre: Medical
ISBN: 0323187366

Acclaimed for its unsurpassed readability and manageable scope, Ashcraft’s Pediatric Surgery presents authoritative, practical guidance on treating the entire range of general surgical and urological problems in infants, children, and adolescents. State-of-the-art, expert coverage equips you to implement all the latest approaches and achieve optimal outcomes for all of your patients. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Make the most effective use of today’s best open and minimally invasive techniques, including single-site umbilical laparoscopic surgery, with guidance from internationally recognized experts in the field. Focus on evidence-based treatments and outcomes to apply today’s best practices. Stay current with timely topics thanks to brand-new chapters on Choledochal Cyst and Gallbladder Disease, Tissue Engineering, and Ethics in Pediatric Surgery, plus comprehensive updates throughout. Hone and expand your surgical skills by watching videos of minimally invasive procedures for recto urethral fistula, biliary atresia, laparoscopic splenectomy, uterine horn, and more. Grasp the visual nuances of surgery from over 1,000 images depicting today’s best surgical practices.

Handbook of Pediatric Surgery

Handbook of Pediatric Surgery
Author: Chandrasen K. Sinha
Publisher: Springer Science & Business Media
Total Pages: 464
Release: 2010-06-25
Genre: Medical
ISBN: 1848821328

Although pediatric surgery is a distinct and evolving specialty, it still remains an integral part of most general surgical and paediatric medical practice. Nevertheless, surgery in children does differ from adult practice in various fundamental ways, and there are key physiological and anatomical differences that constantly need underlining. Progress and improvement in outcome has also been rapid but it is sometimes difficult for practitioners to keep themselves up-to-date with the usual surgical or paediatric text books. This book will give a concise overview of all important topics and is designed to provide information in order to recognise the common surgical conditions; namely typical symptoms and signs, investigation and then treatment management. It will also provide an anatomical and physiological background to aid understanding, in addition to emphasising logical, and where possible, evidence-based practice by the use of flow charts, tables and algorithms. Authored by an international range of leading contributors, this is the first book of its kind to offer comprehensive coverage to this topic in a quick reference, pocket-book format.

Atlas of Pediatric Surgery

Atlas of Pediatric Surgery
Author: Ahmed H. Al-Salem
Publisher: Springer Nature
Total Pages: 896
Release: 2020-01-02
Genre: Medical
ISBN: 3030292118

This book provides a practical guide to the congenital and acquired problems related to pediatric surgery and urology. A range of topics are covered, including; abdominal wall hernias, hemangioma and vascular malformations, gastrochesis, achalasia, congenital gastric outlet obstruction, renal and liver tumors, intestinal malrotation, and hydronephrosis. The book aims to be a quick reference text for the diagnosis and treatment of pediatric surgery conditions and presents information relevant to general surgeons, pediatricians, pediatric surgeons, and medical trainees.

Disorders of Sex Development

Disorders of Sex Development
Author: John M. Hutson
Publisher: Springer Science & Business Media
Total Pages: 311
Release: 2012-01-14
Genre: Medical
ISBN: 3642229646

The rapid advances in medicine over the last 50 years have totally changed the outlook for children with disorders of sex development (DSD), but there is still much to learn. This book crystallizes the combined experience of a leading dedicated unit over 25 years in delivering expert medical and surgical care to children with DSD in a holistic environment. It documents the most recent advances in the molecular biology and embryology of sex development, and describes each disorder in detail. The clinical presentation and approach to diagnosis are described both for babies and for children presenting later in childhood or at adolescence. The chapters on management highlight all the latest knowledge and include the shared wisdom of the authors on current controversies, such as the timing of surgical treatment. Finally, the authors describe their short-, medium-, and long-term outcomes, which demonstrate the strengths of holistic team management.

Environmental Development of the External Genitalia

Environmental Development of the External Genitalia
Author: Ciro Maurizio Amato
Publisher:
Total Pages: 151
Release: 2018
Genre:
ISBN:

Hypospadias is one of the most common birth defects in the world. The incidence of hypospadias has nearly doubled over the past 50 years and now occurs on average in 1 in 125 male newborns each year. Hypospadias is a malformation of the penis where the urethra does not exit at the distal tip, but rather ventrally along the shaft of the penis. The severity of hypospadias depends on the amount of preputial swelling closure, the urethral exit, and the overall shape of the penis. The presence of anti-androgenic and estrogenic endocrine disrupting chemicals (EDCs) in the environment is strongly linked with hypospadias incidence and severity. Still very little is known about the basic biology of penis development, how EDCs perturb normal development, and in-turn there are no known prenatal preventative treatments to protect the developing fetus from EDC exposure and abnormal penis development. In this dissertation I first review the basic biology of penis development. Then using geometric morphometrics I investigate the impact of the anti-androgen, vinclozolin, on morphological changes in the external genitalia. Based on where EDCs impacted penis development the most I then developed a quantitative scoring system to efficiently analyze variation in penis development. The scoring system then was implemented to investigate the temporal and endocrinological drivers of hypospadias severity. Lastly, I used the basic biological information gained to investigate a potential prenatal preventative to protect the developing fetus from EDCs.