Humoral Primary Immunodeficiencies
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| Author | : Mario Milco D'Elios |
| Publisher | : Springer |
| Total Pages | : 383 |
| Release | : 2018-12-29 |
| Genre | : Medical |
| ISBN | : 3319917854 |
This book presents detailed state of the art knowledge on the humoral primary immunodeficiencies (PIDs), i.e., disorders arising from impaired antibody production due to defects intrinsic to B cells or defective interaction between B and T cells. There is extensive coverage of both basic science discoveries and the latest clinical advances in the field. The book is structured in accordance with the most recent classification of PIDs and also covers updates on the B cell immunological synapse. Readers will find comprehensive, in-depth descriptions of novel humoral PID genes and related clinical applications, mucosal B cells, and the various clinical phenotypes of humoral PIDs. Aspects such as differential diagnosis, clinical management in children and adults, and the role of vaccines are also addressed. The authors are all recognized experts from Europe, Australia, and the United States. Humoral Primary Immunodeficiencies will be of high value for immunologists, pediatricians, rheumatologists, oncologists, internists, and infectious disease specialists and will also be informative for MD and PhD students.
| Author | : Kathleen E. Sullivan |
| Publisher | : Academic Press |
| Total Pages | : 1334 |
| Release | : 2020-05-23 |
| Genre | : Medical |
| ISBN | : 0128172959 |
Stiehm's Immune Deficiencies: Inborn Errors in Immunity, Second Edition, is ideal for physicians and other caregivers who specialize in immunology, allergies, infectious diseases and pulmonary medicine. It provides a validated source of information for care delivery to patients, covering approaches to diagnosis that use both new genetic information and emphasize screening strategies. Management has changed dramatically over the past five years, so approaches to infection and autoimmunity are emphasized in an effort to improve outcomes and disseminate new information on the uses of targeted therapy. - Covers immune deficiencies that are presented in a practical way, providing helpful information for active clinicians - Fills an increasingly deep gap in the information available to clinicians - Presents both clinical management and scientific advances for immune deficiencies - Provides a primary resource for physicians in the field of immunodeficiencies - Includes website access to a range of videos relevant to the topics discussed
| Author | : Asghar Aghamohammadi |
| Publisher | : Academic Press |
| Total Pages | : 396 |
| Release | : 2021-01-22 |
| Genre | : Medical |
| ISBN | : 0128231890 |
Awareness among clinicians about PIDs, which consist of more than 400 different entities, plays an important role in ensuring that patients receive a timely diagnosis. Furthermore, clinicians who are educated about PIDs can give their patients access to optimal management of their condition, thus helping the patient achieve a better quality-of-life and long-term prognosis. Inborn Errors of Immunity: A Practical Guide provides the most up-to-date information for busy students, nurses, clinical residents, practicing physicians, and even basic researchers. Readers will benefit from a well-structured breakdown of complicated PID diseases, including approaches to their clinical signs/symptoms and immunologic/laboratory findings. - Presents valuable contribution of more than 40 expert chapter authors, from top centers spanning five continents, each in a specific PID field - Covers various aspects of PID using updated clinical guidelines and standard stepwise pipelines - Focuses on the latest developments in the molecular diagnosis and pathogenesis of diseases, with easy explanation and schematic representation of defective signaling pathways - Includes dedicated sections for clinical features and immunological tests with carefully-curated figures of PID manifestations, imaging, and histological/pathological illustrations to create the first PID medial-color atlas - Summarizes the updated conventional and specific treatments and follow-up notes for different PID diseases
| Author | : Nima Rezaei |
| Publisher | : Springer |
| Total Pages | : 593 |
| Release | : 2016-11-30 |
| Genre | : Medical |
| ISBN | : 3662529092 |
The number of diagnosed cases of primary immunodeficiency diseases (PIDs) – a group of inborn disorders of the immune system – is growing rapidly, but misdiagnosis or late diagnosis still occurs in a significant number of patients, with serious consequences. This is the second edition of a practical reference textbook on PIDs that has been widely welcomed by scientists and clinicians from around the world. The new edition has been extensively revised to reflect advances in knowledge and includes various PIDs not previously covered. For each disease, information is provided on definition, etiology, clinical manifestations, diagnosis, and management. This book will represent an ideal resource for specialists when engaging in diagnosis, clinical decision-making, and treatment planning. It will also prove invaluable for doctors in training and other physicians and nurses who wish to learn more about PIDs.
| Author | : Amos Etzioni |
| Publisher | : Academic Press |
| Total Pages | : 377 |
| Release | : 2014-09-13 |
| Genre | : Medical |
| ISBN | : 0124115543 |
Primary Immunodeficiency Disorders: A Historic and Scientific Perspective provides a complete historical context that is crucial for students and researchers concerned with primary immunodeficiency. When researchers have a poor understanding of the way we arrived where we are in research, they can miss important points about a disease, or miss out on how to approach new diseases. This historical knowledge of research can assist greatly by showing how it was done in the past, demonstrating the successes and failures, so that it can be done better in the future. This book provides an understanding of the process going from clinical problem to lab and back to the clinic, based on historical experiences. Its chapters proceed from the discovery of the T and B cell lineages through the first BMT for immunodeficiency disorder; lab investigation and gene therapy for PID; the discovery of the gene for AT and its function; understanding cytokine defects; and many other stops along the way. - Facilitates communication among physicians and other investigators concerned with immunological and inflammatory diseases - Summarizes for the first time all the known facts from 60 years of primary immunodeficiency research, and teaches how an important field in medicine was established - Provides stimulating discussions on developing new medical therapiesHighlights the importance of studying humans to understand mechanisms of disease that affect humans
| Author | : |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2009 |
| Genre | : Allergy |
| ISBN | : 9780323056595 |
This best-selling resource has a worldwide reputation as the leader in its field. Focusing on human immunology and biology, while also reporting on scientific experimentation and advancement, it provides comprehensive coverage of state-of-the-art basic science as well as authoritative guidance on the practical aspects of day-to-day diagnosis and management. This new edition includes 700 full-color illustrations and a new, more accessible format to make finding information a snap for the busy practitioner. And this Expert Consult Edition offers online access to the complete contents of the 2-volume set, fully searchable, and much more. Includes a glossary of allergy and immunology for quick and easy reference. Contains keypoints and clinical pearls highlighted to find important information quickly. links to useful online resources both for you and for your patients. Offers contributions from hundreds of international authorities for world-class expertise in overcoming any clinical challenge.
| Author | : Samir S. Shah |
| Publisher | : McGraw Hill Professional |
| Total Pages | : 643 |
| Release | : 2015-12-22 |
| Genre | : Medical |
| ISBN | : 0071830510 |
The ONLY handbook on pediatric hospitalist medicine! Focusing specifically on caring for pediatric patients in the hospital setting, this unique handbook addresses more than 350 of the most commonly encountered inpatient pediatric medical conditions. Unlike similar handbooks on the subject, The Philadelphia Guide goes beyond diagnostic strategies to include complete treatment and management guidelines. The emphasis on the treatment of so many inpatient conditions makes the book valuable to anyone who cares for pediatric patients in the hospital – medical students, residents, and pediatric attendings. Designed for immediate access, the handbook features alphabetized clinical sections and consistent chapter subheadings to make the book especially useful at the point of care. Valuable appendices include pediatric vital signs, neonatal codes, and PALS (pediatric advance life support) algorithms Includes evidence-based references NEW 2-color design
| Author | : Raif Geha |
| Publisher | : Garland Science |
| Total Pages | : 353 |
| Release | : 2010-07-29 |
| Genre | : Medical |
| ISBN | : 113515306X |
This book presents case histories to illustrate in a clinical context essential points about the mechanisms of immunity. It includes cases that illustrate both recently discovered genetic immunodeficiencies and some more familiar and common diseases with interesting immunology.
| Author | : Donald Y. M. Leung |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 705 |
| Release | : 2010-10-13 |
| Genre | : Medical |
| ISBN | : 1437737781 |
Pediatric Allergy supplies the comprehensive guidance you need to diagnose, manage, and treat virtually any type of allergy seen in children. Drs. Leung, Sampson, Geha, and Szefler present the new full-color second edition, with coverage of the diagnosis and management of anaphylaxis, the immune mechanisms underlying allergic disease, the latest diagnostic tests, and more. Treat the full range of pediatric allergic and immunologic diseases through clinically focused coverage relevant to both allergists and pediatricians. Understand the care and treatment of pediatric patients thanks to clinical pearls discussing the best approaches. Easily refer to appendices that list common food allergies and autoantibodies in autoimmune diseases. Apply the newest diagnostic tests available—for asthma, upper respiratory allergy, and more—and know their benefits and contraindications. Treat the allergy at its source rather than the resulting reactions through an understanding of the immune mechanisms underlying allergic diseases. Get coverage of new research that affects methods of patient treatment and discusses potential reasons for increased allergies in some individuals. Better manage potential anaphylaxis cases through analysis of contributing facts and progression of allergic disease. Effectively control asthma and monitor its progression using the new step-by-step approach. Eliminate difficulty in prescribing antibiotics thanks to coverage of drug allergies and cross-reactivity.
| Author | : Jennifer A. Namazy |
| Publisher | : Springer |
| Total Pages | : 256 |
| Release | : 2018-12-29 |
| Genre | : Medical |
| ISBN | : 3030033953 |
With insight and research from world-renowned experts, this book provides specific approaches to diagnosis and treatment, addressing pharmacologic and non-pharmacologic management. Specific conditions examined include asthma, rhinitis and sinusitis, anaphylaxis, atopic and contact dermatitis, urticaria and angioedema, hereditary angioedema, drug allergies, and primary immune deficiency. An overview of obstetric management of the high risk asthmatic and allergic patient is provided, and the book concludes with a discussion of the prevention of asthma and allergic diseases during childhood.
