Human Ochratoxicosis And Its Pathologies
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Author | : Eric Edmond Creppy |
Publisher | : John Libbey Eurotext |
Total Pages | : 276 |
Release | : 1993 |
Genre | : Medical |
ISBN | : 9782742000173 |
Among the various mycotoxins affecting man, OTA -- involved in the renal disease endemic in the Balkans -- is thought by the International Cancer Research Centre (ICRC) to be a potential carcinogen. The question facing the international ochratoxin-A specialists was whether endemic renal disease in the Balkans was still restricted to this geographical region. A careful study of human ochratoxicosis and other possibly associated pathologies in under-developed countries could enable future developments of the problems to be forecast in other parts of the globe and hence allow means of preventive action to be sought.
Author | : Wanda M. Haschek |
Publisher | : Elsevier |
Total Pages | : 2160 |
Release | : 2001-10-16 |
Genre | : Medical |
ISBN | : 0080491448 |
A comprehensive understanding of toxicologic pathology is essential for those in industry, academia, and government who make decisions concerning the safety and efficacy of drugs and chemicals. Toxicologic pathology relies heavily on the fields of both toxicology and pathology, which are well covered individually in various texts and references; however, there are few texts that address the field of toxicologic pathology. The Handbook of Toxicologic Pathology fills this void and is thus essential for all health professionals within or interacting with the field of toxicologic pathology. This two-volume set provides the reader with a single reference for toxicologic pathology. In volume I, the book covers toxicologic pathology in its basic aspects, including its definition, the basic biochemical and morphologic mechanisms underlying the discipline, the basic practice of toxicologic pathology (including special techniques) and issues essential to the understanding of toxicologic pathology such as risk assessment, experimental design, and statistical analysis. Next, the book moves to specific issues affecting the "practice" toxicologic pathology, including issues such as knowledge management, regulatory affairs and writing pathology reports. Finally, Volume I closes with several chapters that deal with specific classes of environmental toxicants such as endocrine disruptors and heavy metals. Volume II addresses the toxicologic pathology in a thoroughly standardized systems manner, addressing the basic structure and function of a particular organ system, its response to toxic injury, mechanisms of injury and methods of evaluation of such injury. Key Features * Easy to find, up-to-date reference information * Graphic and photographic plates * Current hot topics and anticipated changes in toxicologic pathology * Standardized chapter format * Topics that are addressed in both a broad and deep manner, resulting in a stand alone text * Added coverage of important environmental toxicants * Chapters authored by internationally recognized experts and peer-reviewed
Author | : A. Logrieco |
Publisher | : Springer Science & Business Media |
Total Pages | : 138 |
Release | : 2013-12-01 |
Genre | : Science |
ISBN | : 9401000018 |
There is an urgent need to expand our knowledge of both the nature of the toxigenic fungi that are widespread on economically-important plants and the effect of their toxic secondary metabolites on human health. Informa tion about the production of mycotoxins by plant pathogens, particularly by species of Fusarium, Aspergillus and Penicillium, their occurrence in infected plants, as well as their role in the plant-pathogen interaction, for example as virulence/pathogenicity factors, is a pre-requisite for preventing plant disease and hence for reducing the Ievels of mycotoxin contamination. Fusarium infections in cereals and other crops are a particular problern world-wide and recent epidemics on wheat in Europe, the USA and Canada have again focused attention on this problem. Fur thermore, species ofAspergillus and Penicillium and their related mycotoxins, particularly Ochratoxin A, represent another consistent problern on cereals and grapes, especially in Europe where 40% of the global grape crop is grown. The aim of this publication is to gather together specialist updated reviews based on papers originally presented during a Workshop of EU Cost Action 835 entitled 'Agriculturally Important Taxigenie Fungi', held in Rome, 7-8 October 1999 at the Plant Pathology Research Institute. We hope the diversity of the contents will stimulate discussion, encourage the sharing of information and result in cross-fertilization of ideas needed for the solution of the present problems. This special issue will be of particular value to interdisciplinary scientists and especially mycologists, mycotoxicologists, plant pathologists and those concerned about the quality of food and food products.
Author | : J. P. Felix D'Mello |
Publisher | : CRC Press |
Total Pages | : 551 |
Release | : 2020-03-27 |
Genre | : Medical |
ISBN | : 100008339X |
First published in 1997. Natural toxicants are the subject of research throughout the world, and they are used for many purposes. The Handbook of Plant and Fungal Toxicants presents a wide range of compounds and considers how they relate to food safety, therapeutic purposes in medicine, and uses in breeding plants for enhanced resistance to insects and disease. Alkaloids, both from plant and fungal sources, are emphasized. Also covered are a variety of toxicants and phytochemicals including: bracken fern poisons polyphenolics gossypol flavones isoflavones pyrimidine glycosides fruit and vegetable allergens linear furanocoumarins photosensitizing agents nitrates oxalates Pinus ponderosa toxicants The text stresses the positive aspects of plant secondary compounds and presents examples of beneficial attributes in the context of environmental protection and human health. An international authorship addresses the global diversity and ecological distribution of plant and fungal toxicants. This handbook is ideal for senior-level college students and post-graduate students studying animal science, toxicology, and pharmaceutical sciences.
Author | : Patrick Fénichel |
Publisher | : John Libbey Eurotext |
Total Pages | : 518 |
Release | : 1995 |
Genre | : Medical |
ISBN | : 9782742000944 |
This valuable reference work provides a synthesis of the latest knowledge about the acrosomatic reaction of human sperm. The acrosomatic reaction, which is a fundamental step in the process of fertilisation, is examined on both the fundamental and clinical levels. Three very recent aspects are also dealt with: what happens to the acrosome during intracytoplasmic microinjections, the usefulness of screening spermatozoa that have completed their acrosomatic reaction, and the development of contraception by a vaccine that targets one of the proteins of the acrosome. International Symposium, Collioure, France, September 1995.
Author | : Ram Lakhan Singh |
Publisher | : Academic Press |
Total Pages | : 405 |
Release | : 2019-07-30 |
Genre | : Medical |
ISBN | : 0128163348 |
Despite advances in hygiene, food treatment, and food processing, diseases caused by foodborne pathogens continue to constitute a worldwide public health concern. Ensuring food safety to protect public health remains a significant challenge in both developing and developed nations. Food Safety and Human Health provides a framework to manage food safety risks and assure a safe food system. Political, economic, and ecological changes have led to the re-emergence of many foodborne pathogens. The globalization of food markets, for example, has increased the challenge to manage the microbial risks. This reference will help to identify potential new approaches in the development of new microbiologically safe foods that will aid in preventing food borne illness outbreaks and provides the basic principles of food toxicology, food processing, and food safety. Food Safety and Human Health is an essential resource to help students, researchers, and industry professionals understand and address day-to-day problems regarding food contamination and safety. - Encompasses the first pedagogic treatment of the entire range of toxic compounds found naturally in foods or introduced by industrial contaminatio - Identifies areas of vital concern to consumers, such as toxicological implications of food, and human health implications of food processing - Focuses on safety aspects of genetically modified foods and the range of processing techniques along with the important food safety laws
Author | : Jagdish Chander |
Publisher | : JP Medical Ltd |
Total Pages | : 958 |
Release | : 2017-11-30 |
Genre | : Medical |
ISBN | : 9386261839 |
Medical mycology refers to the study of fungi that produce disease in humans and other animals, and of the diseases they produce, their ecology, and their epidemiology. This new edition has been fully revised to provide microbiologists with the latest information on fungal infections, covering the entire spectrum of different types of infection, and therapeutic modalities. Beginning with a general overview explaining morphology, taxonomy, and diagnosis, the following sections cover the different categories of fungal infection including superficial cutaneous mycoses, subcutaneous mycoses, systemic mycoses and opportunistic mycoses. A complete section is dedicated to pseudofungal infections. The highly illustrated text concludes with a detailed appendices section and each chapter features key references for further reading. Key points Fully revised, fourth edition providing latest information on the diagnosis and management of fungal infections Covers the entire spectrum of mycoses Highly illustrated with clinical photographs and figures Previous edition (9788188039780) published in 2009
Author | : Joint FAO/WHO Expert Committee on Food Additives. Meeting |
Publisher | : Food & Agriculture Org. |
Total Pages | : 712 |
Release | : 2001 |
Genre | : Aflatoxins |
ISBN | : 9789251046647 |
This volume contains monographs prepared at the fifty-sixth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA). Five mycotoxins or groups of mycotoxins that contaminate food commodities were evaluated at the meeting: aflatoxin M1, fumonisins B1, B2, and B3, ochratoxin A, deoxynivalenol, and T -2 and HT -2 toxins. The monographs in this volume summarize the data that were reviewed on these contaminants, including information on metabolism and toxicity, epidemiology, analytical methods for their measurement in food commodities, sampling protocols, effects of processing, levels and patterns of contamination of food commodities, food consumption, and prevention and control. Based upon this information the Committee assessed the risks associated with intake of these mycotoxins.
Author | : Trevor Burnard |
Publisher | : University of Pennsylvania Press |
Total Pages | : 357 |
Release | : 2016-05-26 |
Genre | : History |
ISBN | : 0812293010 |
Jamaica and Saint-Domingue were especially brutal but conspicuously successful eighteenth-century slave societies and imperial colonies. These plantation regimes were, to adopt a metaphor of the era, complex "machines," finely tuned over time by planters, merchants, and officials to become more efficient at exploiting their enslaved workers and serving their empires. Using a wide range of archival evidence, The Plantation Machine traces a critical half-century in the development of the social, economic, and political frameworks that made these societies possible. Trevor Burnard and John Garrigus find deep and unexpected similarities in these two prize colonies of empires that fought each other throughout the period. Jamaica and Saint-Domingue experienced, at nearly the same moment, a bitter feud between planters and governors, a violent conflict between masters and enslaved workers, a fateful tightening of racial laws, a steady expansion of the slave trade, and metropolitan criticism of planters' cruelty. The core of The Plantation Machine addresses the Seven Years' War and its aftermath. The events of that period, notably a slave poisoning scare in Saint-Domingue and a near-simultaneous slave revolt in Jamaica, cemented white dominance in both colonies. Burnard and Garrigus argue that local political concerns, not emerging racial ideologies, explain the rise of distinctive forms of racism in these two societies. The American Revolution provided another imperial crisis for the beneficiaries of the plantation machine, but by the 1780s whites in each place were prospering as never before—and blacks were suffering in new and disturbing ways. The result was that Jamaica and Saint-Domingue became vitally important parts of the late eighteenth-century American empires of Britain and France.
Author | : Marcel Florkin |
Publisher | : Gulf Professional Publishing |
Total Pages | : 450 |
Release | : 1972 |
Genre | : Biochemistry |
ISBN | : 9780444518668 |