Synthesis of Medicinal Agents from Plants

Synthesis of Medicinal Agents from Plants
Author: Ashish Tewari
Publisher: Elsevier
Total Pages: 384
Release: 2018-04-17
Genre: Science
ISBN: 0081022743

Synthesis of Medicinal Agents from Plants highlights the importance of synthesizing medicinal agents from plants and outlines methods for performing it effectively. Beginning with an introduction to the significance of medicinal plants, the book goes on to provide a historical overview of drug synthesis before exploring how this can be used to successfully replicate and adapt the active agents from natural sources. Chapters then explore the medicinal properties of a number of important plants, before concluding with a discussion of the future of drugs from medicinal plants. Illustrated with real-world examples, it is a practical resource for researchers in this field. In an age of rapid environmental destruction, hundreds of medicinal plants are at risk of extinction from overexploitation and deforestation, limiting the natural resources available for active agent extraction, thereby threatening the discovery of future cures for diseases. Simultaneously, with the increasing population and advances in medical sciences, the demand for drugs is continuously increasing and cannot be met with just plants. The ability to synthetically replicate the active compounds from these plants is essential in creating an ecologically-aware, sustainable future for drug design - Includes detailed coverage of therapeutic compound synthesis - Uses multiple real-world examples to support content - Lays out a sustainable template for the future of developing active agents from natural products

Herbal Medicine

Herbal Medicine
Author: Iris F. F. Benzie
Publisher: CRC Press
Total Pages: 500
Release: 2011-03-28
Genre: Health & Fitness
ISBN: 1439807167

The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef

Pharmacological Properties of Plant-Derived Natural Products and Implications for Human Health

Pharmacological Properties of Plant-Derived Natural Products and Implications for Human Health
Author: George E. Barreto
Publisher: Springer Nature
Total Pages: 603
Release: 2021-04-16
Genre: Medical
ISBN: 3030648729

Medicinal plants and their derived products remain as an indispensable source of bioactive molecules that serve as either drug candidates or lead compounds for drug design and discovery. There are several advantages for plant-derived therapeutics including wide availability, diverse pharmacological actions and a generally good profile of safety and tolerability. Over the recent years, there have been numerous reports from clinical studies testifying to the efficacy and safety of medicinal plants and phytochemicals in ameliorating several human diseases. A plethora of basic studies has also unravelled molecular mechanisms underlying the health benefits of herbal medicines. Nevertheless, issues such as identification of bioactive ingredients, standardization of the products and drug interactions remain to be further studied. In this book, we aim to put together several chapters on the medicinal properties and pharmacological action of medicinal plants, plant species and phytochemicals. The goal is to present a comprehensive collection on most of the therapeutic aspects of plant-derived natural products and molecular mechanisms thereof.

Drug Discovery and Traditional Chinese Medicine

Drug Discovery and Traditional Chinese Medicine
Author: Yuan Lin
Publisher: Boom Koninklijke Uitgevers
Total Pages: 268
Release: 2001-07-31
Genre: Medical
ISBN: 9780792374114

There has been a growing interest in the use of traditional Chinese medicine (TCM) both in China and globally. In China, increased health care costs are associated with the widespread use of Western drugs and their related side-effects. Currently two-thirds of the drugs used in China are of Western origin while the other third is TCM. Health care costs can be more effectively controlled by wider use of TCM. Such trends provide an opportunity to develop a pharmaceutical industry based on herbal products for both the Chinese and global markets. Internationally, the World Health Organization has noted that a majority of the populations of developing countries mainly relies on traditional herbal formulations. Therefore, standardized and effective herbal medicines can play an important role in health care. All of this coincides with the growing use of herbal medicines in industrialized countries. To date, very little scientifically sound research on TCM has been published in English. This book is meant to provide the English-speaking world with a collection of papers on this important subject, covering such topics as research and development, clinical studies, and commercialization.

Toxicological Survey of African Medicinal Plants

Toxicological Survey of African Medicinal Plants
Author: Victor Kuete
Publisher: Elsevier
Total Pages: 742
Release: 2014-05-30
Genre: Medical
ISBN: 0128004754

Toxicological Survey of African Medicinal Plants provides a detailed overview of toxicological studies relating to traditionally used medicinal plants in Africa, with special emphasis on the methodologies and tools used for data collection and interpretation. The book considers the physical parameters of these plants and their effect upon various areas of the body and human health, including chapters dedicated to genotoxicity, hepatotoxicity, nephrotoxicity, cardiotoxicity, neurotoxicity, and specific organs and systems.Following this discussion of the effects of medicinal plants is a critical review of the guidelines and methods in use for toxicological research as well as the state of toxicology studies in Africa. With up-to-date research provided by a team of experts, Toxicological Survey of African Medicinal Plants is an invaluable resource for researchers and students involved in pharmacology, toxicology, phytochemistry, medicine, pharmacognosy, and pharmaceutical biology. - Offers a critical review of the methods used in toxicological survey of medicinal plants - Provides up-to-date toxicological data on African medicinal plants and families - Serves as a resource tool for students and scientists in the various areas of toxicology

The Role of Natural Products in Drug Discovery

The Role of Natural Products in Drug Discovery
Author: J. Mulzer
Publisher: Springer Science & Business Media
Total Pages: 363
Release: 2013-04-17
Genre: Medical
ISBN: 3662040425

Natural Products have been important sources of useful drugs from prehistoric times to the present. This book gives an overview about this field and provides important recent contributions to the discovery of new drugs generated by research on natural products. Total synthesis of natural products with interesting biological activities is paving the way for the preparation of new and improved analogs. The methods of combinatorial chemistry permit the selection of the best drug from a large number of candidates. Beyond synthesis and evaluation of organic molecules a number of new bioorganic methods are coming to the fore and will be discucced in this isue of the ERnst schering Research Foundation workshop proceedings.

Advanced Pharmacological Uses of Medicinal Plants and Natural Products

Advanced Pharmacological Uses of Medicinal Plants and Natural Products
Author: Singh, Ajeet
Publisher: IGI Global
Total Pages: 442
Release: 2020-02-21
Genre: Medical
ISBN: 1799820955

A vast majority of the world’s population lacks access to essential medicines and the provision of safe healthcare services. Medicinal plants and herbal medicines can be applied for pharmacognosy, or the discovery of new drugs, or as an aid for plant physiology studies. In recent years, there has been increased interest in the search for new chemical entities and the expression of resistance of many drugs available in the market has led to a shift in paradigm towards medicinal research. Herbal treatments, the most popular form of folk medicine, may become an important way of increasing access to healthcare services. Advanced Pharmacological Uses of Medicinal Plants and Natural Products provides emerging research exploring the theoretical and practical aspects of drug discovery from natural sources that allow for the effective treatment of human health problems without any side effects, toxicity, or drug resistance. Featuring coverage on a broad range of topics such as ethnobotany, therapeutic applications, and bioactive compounds, this book is ideally designed for pharmacologists, scientists, ethnobotanists, botanists, health researchers, professors, industry professionals, and health students in fields that include pharmaceutical drug development and discovery.

Herbal Biomolecules in Healthcare Applications

Herbal Biomolecules in Healthcare Applications
Author: Subhash C. Mandal
Publisher: Academic Press
Total Pages: 752
Release: 2021-10-05
Genre: Medical
ISBN: 0323900801

Herbal Biomolecules in Healthcare Applications presents extensive detailed information on all the vital principles, basics and fundamental aspects of multiple herbal biomolecules in the healthcare industry. This book examines important herbal biomolecules including alkaloids, glycosides, flavonoids, anthraquinones, steroids, polysaccharides, tannins and polyphenolic compounds, terpenes, fats and waxes, proteins and peptides, and vitamins. These herbal biomacromolecules are responsible for different bioactivities as well as pharmacological potentials. A systematic understanding of the extraction, purification, characterization, applications of these herbal biomolecules and their derivatives in healthcare fields is developed in this comprehensive book. Chapters explore the key topics along with an emphasis on recent research and developments in healthcare fields by leading experts. They include updated literature review of the relevant key topics, good quality illustrations, chemical structures, flow charts, well-organized tables and case studies. Herbal Biomolecules in Healthcare Applications will be useful for researchers working on natural products and biomolecules with bioactivity and nutraceutical properties. Professionals specializing in scientific areas such as biochemistry, pharmacology, analytical chemistry, organic chemistry, clinics, or engineering focused on bioactive natural products will find this book useful. - Provides a study of different type of biomolecules from herbal extracts and their bioactivities as well as their application in the healthcare industry - Contributions by global leaders and experts from academia, industry and regulatory agencies, who have been considered as pioneers in the application of herbal biomolecules in the diverse healthcare fields - Includes updated literature review along with practical examples and research case studies

Phytochemicals in Human Health Protection, Nutrition, and Plant Defense

Phytochemicals in Human Health Protection, Nutrition, and Plant Defense
Author: Phytochemical Society of North America. Meeting
Publisher: Springer Science & Business Media
Total Pages: 448
Release: 1999-09-30
Genre: Medical
ISBN: 0306462036

Proceedings of the 38th Annual Meeting at the Phytochemical Society of North America on Phytochemicals in Human Health Protection, Nutrition and Plant Defense, held July 26-31, 1998 in Pullman, WA, USA

Plant-derived Natural Products

Plant-derived Natural Products
Author: Anne E. Osbourn
Publisher: Springer Science & Business Media
Total Pages: 588
Release: 2009-07-07
Genre: Science
ISBN: 0387854983

Plants produce a huge array of natural products (secondary metabolites). These compounds have important ecological functions, providing protection against attack by herbivores and microbes and serving as attractants for pollinators and seed-dispersing agents. They may also contribute to competition and invasiveness by suppressing the growth of neighboring plant species (a phenomenon known as allelopathy). Humans exploit natural products as sources of drugs, flavoring agents, fragrances and for a wide range of other applications. Rapid progress has been made in recent years in understanding natural product synthesis, regulation and function and the evolution of metabolic diversity. It is timely to bring this information together with contemporary advances in chemistry, plant biology, ecology, agronomy and human health to provide a comprehensive guide to plant-derived natural products. Plant-derived natural products: synthesis, function and application provides an informative and accessible overview of the different facets of the field, ranging from an introduction to the different classes of natural products through developments in natural product chemistry and biology to ecological interactions and the significance of plant-derived natural products for humans. In the final section of the book a series of chapters on new trends covers metabolic engineering, genome-wide approaches, the metabolic consequences of genetic modification, developments in traditional medicines and nutraceuticals, natural products as leads for drug discovery and novel non-food crops.