Anti-aging Drugs

Anti-aging Drugs
Author: Alexander M Vaiserman
Publisher: Royal Society of Chemistry
Total Pages: 592
Release: 2017-01-18
Genre: Medical
ISBN: 1782629858

Aging is a natural phenomenon that is peculiar to all living things. However, accumulating findings indicate that senescence could be postponed or prevented by certain approaches. Substantial evidence has emerged supporting the possibility of radical human health and lifespan extension, in particular through pharmacological modulation of aging. A number of natural dietary ingredients and synthetic drugs have been assumed to have geroprotective potential. In the development of anti-aging therapeutics, several cell, insect, and animal models may provide useful starting points prior to human studies. This book provides an overview of current research aimed to search for life-extending medications and describes pharmacological aspects of anti-aging medicine. Readers are introduced to the fascinating historical background of geroprotection in the first chapter. In-depth information on models for investigating geroprotective drugs precedes a section covering anti-aging properties of pharmaceutical compounds, such as calorie restriction mimetics, autophagy inducers, senolytics and mitochondrial antioxidants. Finally, strategies to translate discoveries from aging research into drugs and healthcare policy perspectives on anti-ageing medicine are provided to give a complete picture of the field. A timely and carefully edited collection of chapters by leading researchers in the field, this book will be a fascinating and useful resource for pharmacologists, gerontologists and any scientifically interested person wishing to know more about the current status of research into anti-aging remedies, challenges and opportunities.

Live Younger Longer

Live Younger Longer
Author: Stephen Kopecky
Publisher: Simon and Schuster
Total Pages: 306
Release: 2022-02-16
Genre: Health & Fitness
ISBN: 1945564377

Most of us want to live a long, healthy life, but how do we do that? Drawing upon lessons from his own life, Mayo Clinic cardiologist Stephen Kopecky offers a holistic, evidence-based approach to preventing common diseases and chronic illnesses and living a longer life of pleasure and purpose. In the past century, the leading causes of death around the world have shifted from infectious diseases to long-term chronic illnesses. What’s killing us today isn’t so much flu or tuberculosis, but heart disease and cancer. In fact, more than 1.2 million Americans die from these two diseases each year. Paradoxically, these chronic diseases are a consequence of living longer than ever. But even if we’re living longer, are we living better? The overwhelming number of people now living under the burden of chronic illness indicates otherwise. After surviving two bouts of cancer, Dr. Stephen Kopecky, M.D set out to discover the behaviors people can adopt to live longer lives free of chronic illnesses and diseases. What he discovered was that the answer lies in just six habits that require small changes to your daily life, but reap big results long-term. From adopting better diet and exercise habits to managing stress and sleep, these behaviors will not only preserve your health, they can improve your quality of living and extend your life. The secret, however, lies not just in the steps themselves but in how you accomplish them. This book offers in-depth insights on: The best foods to eat and why Increasing physical activity and improving fitness Why your sleep habits matter The dangers of stress and what to do about them The true impact of alcohol and tobacco on our bodies How to make changes that will last a lifetime After 30 years of research in the field of cardiovascular disease prevention, Dr. Kopecky is sharing what he’s learned from his practice and own personal experience about staying healthy, preventing chronic illnesses, and living younger longer.

The Age-Well Project

The Age-Well Project
Author: Annabel Streets
Publisher: Piatkus Books
Total Pages: 354
Release: 2021-05-06
Genre: Health & Fitness
ISBN: 9780349419695

Diseases of older age take root decades before symptoms appear. For a longer, happier life, we need to plan ahead - but what exactly should we do? For five years, Annabel Streets and Susan Saunders immersed themselves in the latest science of longevity, radically overhauling their lives and documenting their findings on their popular blog. After reading hundreds of studies and talking to numerous experts, Annabel and Susan have compiled almost 100 short cuts to health in mid and later life, including: how, when and what to eat; the supplements worth taking; when, where and how to exercise; the most useful medical tests; how to avoid health-threatening chemicals; the best methods for keeping the brain sharp; and how to sleep better.

Stupid Things I Won't Do When I Get Old

Stupid Things I Won't Do When I Get Old
Author: Steven Petrow
Publisher: Citadel
Total Pages: 274
Release: 2021-06-29
Genre: Self-Help
ISBN: 0806541008

For fans of David Sedaris and Nora Ephron, a humorous, irreverent, and poignant look at the gifts, stereotypes, and inevitable challenges of aging, based on award-winning journalist Steven Petrow's wildly popular New York Times essay, "Things I'll Do Differently When I Get Old." Soon after his 50th birthday, Petrow began assembling a list of “things I won’t do when I get old”—mostly a catalog of all the things he thought his then 70-something year old parents were doing wrong. That list, which included “You won’t have to shout at me that I’m deaf,” and “I won’t blame the family dog for my incontinence,” became the basis of this rousing collection of do’s and don’ts, wills and won’ts that is equal parts hilarious, honest, and practical. The fact is, we don’t want to age the way previous generations did. “Old people” hoard. They bore relatives—and strangers alike—with tales of their aches and pains. They insist on driving long after they’ve become a danger to others (and themselves). They eat dinner at 4pm. They swear they don’t need a cane or walker (and guess what happens next). They never, ever apologize. But there is another way... In Stupid Things I Won’t Do When I Get Old, Petrow candidly addresses the fears, frustrations, and stereotypes that accompany aging. He offers a blueprint for the new old age, and an understanding that aging and illness are not the same. As he writes, “I meant the list to serve as a pointed reminder—to me—to make different choices when I eventually cross the threshold to ‘old.’” Getting older is a privilege. This essential guide reveals how to do it with grace, wisdom, humor, and hope. And without hoarding. Praise for Stupid Things I Won't Do When I Get Old: “Unbelievably witty and relatable, I alternated bursting into laughter and placing my hand over my face in horror thinking, Oh my God, is that me? I often say, at this age we have something young people can never have…wisdom. My dear friend, Steven Petrow, has wisdom to share in this honest, funny, wry guide to keep us young at heart, without desperately hanging onto our youth. I am buying this book for all of my friends!” —Suzanne Somers, New York Times bestselling author of A New Way to Age “Stupid Things I Won’t Do When I Get Old is an irreverent, funny, honest look at aging and all the things we take for granted as normal parts of aging. They don’t need to be. If you struggle with getting older and want to find a fresh perspective on lessons learned about what NOT to do as we age, and what TO do to stay young in heart, spirit, mind and body, read this book.” —Mark Hyman, MD, #1 New York Times bestseller author of The Blood Sugar Solution 10-Day Detox Diet, and Head of Strategy and Innovation at the Cleveland Clinic Center for Functional Medicine. “Steven Petrow resolved to do things differently than his parents had when he gets old because he wished they’d been able to enjoy life more. His solution? He created a list! In this book, he shares the secrets to living a full life regardless of our age. It's all about the decisions we make every day. My advice in a nutshell: Read this book and keep it handy.” —“Dear Abby” (Jeanne Phillips), nationally syndicated advice columnist “It’s never too early to imagine what your life will look like as you age. And as I once wrote, ‘We are not hostages to our fate.’ Petrow’s book will help you plan, think, and redefine what it means to get older—and even laugh while doing it.” —Andrew Weil, MD, New York Times bestselling author of Spontaneous Healing and Healthy Aging: A Lifelong Guide to Your Well-Being “Steven Petrow not only has a great attitude about life, he is wise about how to live it. Like me, he says we should embrace our one life 100% and not let a number—our age—get in the way of anything! Steven’s book will help you rethink the word “aging” and approach this next chapter with a positive and proactive attitude. Plus, this book is fun!” —Denise Austin, renowned fitness expert, author, and columnist “Steven’s writing feels like sitting with a friend—one who is unusually gracious, warm and frank.” —Carolyn Hax, author of the nationally syndicated advice column, Carolyn Hax Praise for Steven Petrow: "Steven Petrow's Complete Gay & Lesbian Manners helps gays and straights navigate the subtleties of the same-sex world." —People "Move over, Emily Post! When it comes to etiquette for members of the gay, lesbian, bisexual and transgender community—as well as their straight friends, family members and coworkers--author and journalist Steven Petrow is the authority." —TIME "What could've easily become a novelty book has emerged as an exhaustively researched, essential resource thanks to advice columnist and etiquette expert Steven Petrow." —The Advocate "From having kids to planning funerals, Steven Petrow's Complete Gay & Lesbian Manners has most facets of gay life covered. Ms. Post would approve." —Entertainment Weekly "An indispensable refresher course...on what's proper in modern...life." —Kirkus Reviews

The Blue Zones Challenge

The Blue Zones Challenge
Author: Dan Buettner
Publisher: Disney Electronic Content
Total Pages: 196
Release: 2022-01-11
Genre: Cooking
ISBN: 1426222270

In this companion to the number one New York Times bestseller The Blue Zones Kitchen, Dan Buettner offers a four-week guide and year-long sustainability program to jump-start your journey to better health, happiness, less stress, and a longer life. Get started on the path to a longer, healthier, happier life with this quick start to building your own Blue Zones lifestyle. Dan Buettner, founder of the Blue Zones and author of the New York Times number one best-selling Blue Zones Kitchen, offers the challenge of a lifetime: Build a foundation for better nutrition, more exercise, and a stronger social life that will extend your lifetime by years. In this easy-to-implement guide, you'll start with the rules of the Blue Zones Challenge, including tips and tricks from the five Blue Zones--locations around the world where people consistently live to 100--advice for setting up a successful kitchen and pantry, and resources for expanding you support network. Then, follow week-by-week prompts to Change your diet Increase your activity Update your living spaces Build your social life. After four weeks--and with the help of journaling tips and delicious recipes--you'll see results in your weight, your well-being, and your general health. From there, follow the Blue Zones challenge through the rest of the year with an 11-month sustainability plan that will continue to encourage you and build upon the foundation you've already started. What you'll find is living to 100 is easy--it just takes following the Blue Zones way!

Business Engagement in Building Healthy Communities

Business Engagement in Building Healthy Communities
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 139
Release: 2015-05-08
Genre: Medical
ISBN: 0309316693

Business Engagement in Building Healthy Communities is the summary of a workshop convened by the Institute of Medicine's Roundtable on Population Health Improvement in July 2014 to consider the role of business in improving population health beyond the usual worksite wellness and health promotion activities. The workshop followed previous roundtable discussions on the importance of applying a health lens to decision making in non-health sectors and the need for cross-sector collaborations to advance population health. Invited speakers included representatives from several businesses that have taken action to improve the health of their communities and representatives of business coalitions on health. The workshop was designed to discuss why engaging in population health improvement is good for business; explore how businesses can be effective key leaders in improving the health of communities; and discuss ways in which businesses can engage in population health improvement. This report is a record of the presentations and discussion of the event

100 Plus

100 Plus
Author: Sonia Arrison
Publisher: Basic Books
Total Pages: 244
Release: 2011-08-23
Genre: Medical
ISBN: 0465027709

Humanity is on the cusp of an exciting longevity revolution. The first person to live to 150 years has probably already been born.What will your life look like when you live to be over 100? Will you be healthy? Will your marriage need a sunset clause? How long will you have to work? Will you finish one career at sixty-five only to go back to school to learn a new one? And then, will you be happily working for another sixty years? Maybe you'll be a parent to a newborn and a grandparent at the same time. Will the world become overpopulated? And how will living longer affect your finances, your family life, and your views on religion and the afterlife?In 100 Plus, futurist Sonia Arrison takes us on an eye-opening journey to the future at our doorsteps, where science and technology are beginning to radically change life as we know it. She introduces us to the people transforming our lives: the brilliant scientists and genius inventors and the billionaires who fund their work. The astonishing advances to extend our lives -- and good health -- are almost here. In the very near future fresh organs for transplants will be grown in laboratories, cloned stem cells will bring previously unstoppable diseases to their knees, and living past 100 will be the rule, not the exception.Sonia Arrison brings over a decade of experience researching and writing about cutting-edge advances in science and technology to 100 Plus, painting a vivid picture of a future that only recently seemed like science fiction, but now is very real. 100 Plus is the first book to give readers a comprehensive understanding of how life-extending discoveries will change our social and economic worlds. This illuminating and indispensable text will help us navigate the thrilling journey of life beyond 100 years.

Aging Well

Aging Well
Author: George E. Vaillant
Publisher: Hachette+ORM
Total Pages: 354
Release: 2008-12-12
Genre: Psychology
ISBN: 0316054801

“An outstanding contribution to the study of aging” from a psychiatrist and professor at Harvard Medical School (Publishers Weekly). In an unprecedented series of studies, Harvard Medical School has followed 824 subjects—men and women, some rich, some poor—from their teens to old age. Harvard's George Vaillant now uses these studies—the most complete ever done anywhere in the world—and the subjects' individual histories to illustrate the factors involved in reaching a happy, healthy old age. He explains precisely why some people turn out to be more resilient than others, the complicated effects of marriage and divorce, negative personality changes, and how to live a more fulfilling, satisfying and rewarding life in the later years. He shows why a person's background has less to do with their eventual happiness than the specific lifestyle choices they make. And he offers step-by-step advice about how each of us can change our lifestyles and age successfully. Sure to be debated on talk shows and in living rooms, Vaillant's definitive and inspiring book is the new classic account of how we live and how we can live better. It will receive massive media attention, and with good reason: we have never seen anything like it, and what it has to tell us will make all the difference in the world. “A respected researcher. . . . offers suggestions for successful and happy aging. Highly recommended.” —Library Journal “Astonishing observations. . . . [Aging Well] provides the only available longitudinal assessment of the factors that will permit us to age well.” —New England Journal of Medicine “Perceptive, understanding, and often tinged with delightful humor.” —Booklist

The Longevity Code

The Longevity Code
Author: Kris Verburgh
Publisher: The Experiment
Total Pages: 322
Release: 2019-12-24
Genre: Health & Fitness
ISBN: 1615194975

Slow down the aging process and live well for longer Do you know exactly how and why you age? And what you can do—whatever your current age—to slow that process and have a longer, healthier life? In The Longevity Code, medical doctor Kris Verburgh illuminates the biological mechanisms that make our bodies susceptible to heart attacks, dementia, diabetes, and other aging-related diseases. With the facts laid out, he provides the tools we need to slow down the aging process. His scientifically backed Longevity Staircase outlines a simple yet innovative step-by-step method offering better health and a longer life span– especially the crucial role of proper nutrition and exercise. But diet and exercise might not be the only way to crack the “longevity code”: With each passing day, advances in biotechnology that were once the stuff of science fiction are emerging. Dr. Verburgh discusses how new types of vaccines, mitochondrial DNA, CRISPR proteins, and stem cells may help us slow and even reverse aging—now and in the future—and when paired with the right lifestyle, lead to longer, healthier lives than we’ve ever imagined.