How Medicines Are Born The Imperfect Science Of Drugs
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| Author | : Lisa Vozza |
| Publisher | : World Scientific |
| Total Pages | : 186 |
| Release | : 2017-05-05 |
| Genre | : Medical |
| ISBN | : 1786343002 |
This book is an excursion into the drug development process, from the initial conception in a chemical or molecular biology lab, via tests in isolated cells and animals, to the stage of clinical trials. The human body is a complex ecosystem where little is conclusively known in terms of its response to medication, for both sick and healthy individuals. The considerable degree of uncertainty inherent in health-related research can lead to approval of controversial medicines, particularly in high-stakes scenarios and medical crises. Real-life examples are drawn on here to explain the decision making processes behind the acceptance of new drugs, disproving misconceptions around medicines by delving into the history and current practice of the drug development process.Originally written in Italian, How Medicines are Born helps patients, students, public health officials physicians, healthcare practitioners and biomedical scientists make informed decisions on the benefits and disadvantages of select medicine based on an understanding of the history of drug development.Published in Italian (2014), M D'Incalci & L Vozza, Come Nascono le Medicine; La scienza imperfetta dei farmaci. Bologna: ZanichelliRelated Link(s)
| Author | : Lisa Vozza |
| Publisher | : |
| Total Pages | : 186 |
| Release | : 2017 |
| Genre | : MEDICAL |
| ISBN | : 9781786342997 |
"This book is an excursion into the drug development process, from the initial conception in a chemical or molecular biology lab, via tests in isolated cells and animals, to the stage of clinical trials. The human body is a complex ecosystem where little is conclusively known in terms of its response to medication, for both sick and healthy individuals. The considerable degree of uncertainty inherent in health-related research can lead to approval of controversial medicines, particularly in high-stakes scenarios and medical crises. Real-life examples are drawn on here to explain the decision making processes behind the acceptance of new drugs, disproving misconceptions around medicines by delving into the history and current practice of the drug development process. Originally written in Italian, How Medicines are Born helps patients, students, public health officials physicians, healthcare practitioners and biomedical scientists make informed decisions on the benefits and disadvantages of select medicine based on an understanding of the history of drug development. Published in Italian (2014), M D'Incalci & L Vozza, Come Nascono le Medicine; La scienza imperfetta dei farmaci. Bologna: Zanichelli"--Publisher's website.
| Author | : Brian Edwards |
| Publisher | : World Scientific |
| Total Pages | : 368 |
| Release | : 2021-05-28 |
| Genre | : Medical |
| ISBN | : 9811231397 |
The Dark Side of Healthcare draws uncomfortable lessons from over 300 case studies of events that occurred in the healthcare sector. Health services have many skilled and dedicated professionals but there is a dark side that cannot be ignored. The unthinkable has happened and might have been prevented.The case studies from many countries include serial killers with a health background, drugs and medical devices that proved to be dangerous, negligent and poor clinical practices, as well as incompetent and weak management that led to failing hospitals and harm to patients. There are also corruption cases, accidents at work, and cases involving the sexual exploitation of children. Politicians' early responses to COVID-19 and the subsequent missteps are also scrutinised. Many of the errors and omissions that led to patient harm have been repeated.This book is not an attack on health services or health professionals. Instead, it is a search for ways of making health delivery safer for patients and staff who deliver care often in challenging circumstances. Its focus is learning rather than blame.
| Author | : Andrea Grignolio |
| Publisher | : Springer |
| Total Pages | : 185 |
| Release | : 2018-07-13 |
| Genre | : Medical |
| ISBN | : 3319681060 |
The dangerous decline in vaccinations in many developed countries is at the heart of a lively debate that confirms how important the subject is today. Vaccinations are among mankind’s most important scientific discoveries, yet they continue to be viewed with suspicion by part of the public – the victims of disinformation campaigns, instrumentalization and unfounded fears. There is, however, also an evolutionary explanation for these irrational beliefs, and countering the growing social opposition will be extremely difficult without grasping it. This book, which sheds new light on the safety and importance of vaccinations, is intended both for parents and those readers who want to understand the role of vaccinations in contemporary society, where the ease of access to knowledge is both a great opportunity and a great responsibility. The chapters follow a historical progression and conclude with a discussion of the most recent cognitive theories on how to overcome this opposition to vaccinations.
| Author | : Ben Goldacre |
| Publisher | : Farrar, Straus and Giroux |
| Total Pages | : 449 |
| Release | : 2013-02-05 |
| Genre | : Business & Economics |
| ISBN | : 0374710171 |
We like to imagine that medicine is based on evidence and the results of fair testing and clinical trials. In reality, those tests and trials are often profoundly flawed. We like to imagine that doctors who write prescriptions for everything from antidepressants to cancer drugs to heart medication are familiar with the research literature about a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by the pharmaceutical industry. We like to imagine that regulators have some code of ethics and let only effective drugs onto the market, when in reality they approve useless drugs, with data on side effects casually withheld from doctors and patients. All these problems have been shielded from public scrutiny because they're too complex to capture in a sound bite. But Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct in the medical industry affects us on a global scale. With Goldacre's characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for regulation. This is the pharmaceutical industry as it has never been seen before.
| Author | : F. Perry Wilson |
| Publisher | : Grand Central Publishing |
| Total Pages | : 275 |
| Release | : 2023-01-24 |
| Genre | : Medical |
| ISBN | : 153872362X |
Blending personal anecdotes with hard science, an accomplished physician, researcher, and science communicator gives you the tools to avoid medical misinformation and take control of your health: "A brilliant step toward patients and physicians alike reclaiming a sense of confidence in a system that often feels overwhelming and mismanaged" (Gabby Bernstein, #1 New York Times bestselling author of The Universe Has Your Back). We live in an age of medical miracles. Never in the history of humankind has so much talent and energy been harnessed to cure disease. So why does it feel like it’s getting harder to live our healthiest lives? Why does it seem like “experts” can’t agree on anything, and why do our interactions with medical professionals feel less personal, less honest, and less impactful than ever? Through stories from his own practice and historical case studies, Dr. F. Perry Wilson, a physician and researcher from the Yale School of Medicine, explains how and why the doctor-patient relationship has eroded in recent years and illuminates how profit-driven companies—from big Pharma to healthcare corporations—have corrupted what should have been medicine’s golden age. By clarifying the realities of the medical field today, Dr. Wilson gives readers the tools they need to make informed decisions, from evaluating the validity of medical information online to helping caregivers advocate for their loved ones, in the doctor’s office and with the insurance company. Dr. Wilson wants readers to understand medicine and medical science the way he does: as an imperfect and often frustrating field, but still the best option for getting well. To restore trust between patients, doctors, medicine, and science, we need to be honest, we need to know how to spot misinformation, and we need to avoid letting skepticism ferment into cynicism. For it is only by redefining what “good medicine” is—science that is well-researched, rational, safe, effective, and delivered with compassion, empathy, and trust—that the doctor-patient relationship can be truly healed.
| Author | : Paul Starr |
| Publisher | : |
| Total Pages | : 532 |
| Release | : 1982 |
| Genre | : History |
| ISBN | : 9780465079353 |
Winner of the 1983 Pulitzer Prize and the Bancroft Prize in American History, this is a landmark history of how the entire American health care system of doctors, hospitals, health plans, and government programs has evolved over the last two centuries. "The definitive social history of the medical profession in America....A monumental achievement."—H. Jack Geiger, M.D., New York Times Book Review
| Author | : Lauren Slater |
| Publisher | : Little, Brown |
| Total Pages | : 361 |
| Release | : 2018-02-20 |
| Genre | : Medical |
| ISBN | : 0316370584 |
The explosive story of the discovery and development of psychiatric medications, as well as the science and the people behind their invention, told by a riveting writer and psychologist who shares her own experience with the highs and lows of psychiatric drugs. Although one in five Americans now takes at least one psychotropic drug, the fact remains that nearly seventy years after doctors first began prescribing them, not even their creators understand exactly how or why these drugs work -- or don't work -- on what ails our brains. Lauren Slater's revelatory account charts psychiatry's journey from its earliest drugs, Thorazine and lithium, up through Prozac and other major antidepressants of the present. Blue Dreams also chronicles experimental treatments involving Ecstasy, magic mushrooms, the most cutting-edge memory drugs, placebos, and even neural implants. In her thorough analysis of each treatment, Slater asks three fundamental questions: how was the drug born, how does it work (or fail to work), and what does it reveal about the ailments it is meant to treat? Fearlessly weaving her own intimate experiences into comprehensive and wide-ranging research, Slater narrates a personal history of psychiatry itself. In the process, her powerful and groundbreaking exploration casts modern psychiatry's ubiquitous wonder drugs in a new light, revealing their ability to heal us or hurt us, and proving an indispensable resource not only for those with a psychotropic prescription but for anyone who hopes to understand the limits of what we know about the human brain and the possibilities for future treatments.
| Author | : |
| Publisher | : |
| Total Pages | : 804 |
| Release | : 1998 |
| Genre | : Medical jurisprudence |
| ISBN | : |
| Author | : Sergio Sismondo |
| Publisher | : |
| Total Pages | : 231 |
| Release | : 2018 |
| Genre | : Drugs |
| ISBN | : 9780995527782 |
