The Integrated Guidelines for Developing Epidemiologic Profiles: HIV Prevention and Ryan White CARE Act Community Planning have been developed by the Centers for Disease Control and Prevention and the Health Resources Services Administration to assist the persons who compile and interpret HIV prevention and care data for state, territorial, or local HIV/AIDS epidemiologic profiles. The purpose of the document is to provide one set of guidelines to help profile writers produce integrated epidemiologic profiles and advise them concerning how to interpret epidemiologic data in ways that are consistent and useful in meeting prevention and care planning needs. An example of an integrated epidemiologic profile from Louisiana is also included in this document.