Heteroatom Manipulation
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Author | : E. Winterfeldt |
Publisher | : Elsevier |
Total Pages | : 1217 |
Release | : 1992-09-08 |
Genre | : Science |
ISBN | : 0080912494 |
In this volume, those functional groups containing heteroatoms that have gained importance in organic synthesis are dealt with in detail. The introduction of these various groups and their relevant transformations are described and the various aspects of chemoselectivity, regioselectivity and stereoselectivity are discussed. After a compilation of the synthetically most useful substitution processes, there is a series of chapters on the various types of acylation reactions and in this context the different methods of acyl group activation are discussed. As functional group protection is of very general importance for organic synthesis, a corresponding chapter is included. This is followed by a section on the preparation of carbonyl derivatives and the most important transformations and rearrangements of functional group derivatives. At the end of the volume one finds chapters on all types of elimination reactions and related thermal reactions together with a survey on fragmentation processes in organic synthesis.
Author | : |
Publisher | : |
Total Pages | : 1226 |
Release | : 1991 |
Genre | : Chemistry, Organic |
ISBN | : |
Author | : |
Publisher | : Newnes |
Total Pages | : 9815 |
Release | : 2014-02-14 |
Genre | : Science |
ISBN | : 008097743X |
The second edition of Comprehensive Organic Synthesis—winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers—builds upon the highly respected first edition in drawing together the new common themes that underlie the many disparate areas of organic chemistry. These themes support effective and efficient synthetic strategies, thus providing a comprehensive overview of this important discipline. Fully revised and updated, this new set forms an essential reference work for all those seeking information on the solution of synthetic problems, whether they are experienced practitioners or chemists whose major interests lie outside organic synthesis. In addition, synthetic chemists requiring the essential facts in new areas, as well as students completely new to the field, will find Comprehensive Organic Synthesis, Second Edition, Nine Volume Set an invaluable source, providing an authoritative overview of core concepts. Winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers Contains more than170 articles across nine volumes, including detailed analysis of core topics such as bonds, oxidation, and reduction Includes more than10,000 schemes and images Fully revised and updated; important growth areas—including combinatorial chemistry, new technological, industrial, and green chemistry developments—are covered extensively
Author | : Barry M. Trost |
Publisher | : Elsevier |
Total Pages | : 1174 |
Release | : 1991 |
Genre | : Science |
ISBN | : 9780080405995 |
Author | : Mohan Lal Kolhe |
Publisher | : Springer Nature |
Total Pages | : 311 |
Release | : |
Genre | : |
ISBN | : 9819736862 |
Author | : Barry M. Trost |
Publisher | : Elsevier |
Total Pages | : 1328 |
Release | : 1991 |
Genre | : Science |
ISBN | : 9780080405957 |
Volume 4 focuses on additions and the resulting substitutions at carbon-carbon &pgr;-bonds. Part 1 includes processes generally considered as simple polar reactions, reactive electrophiles and nucleophiles adding to alkenes and alkynes. A major topic is Michael-type addition to electron deficient &pgr;-bonds, featured in the first six chapters. In part 2 are collected the four general processes leading to nucleophilic aromatic substitution, including radical chain processes and transition metal activation through to &pgr;-complexation. Metal-activated addition (generally by nucleophiles) to alkenes and polyenes is presented in part 3, including allylic alkylation catalyzed by palladium. The coverage of nonpolar additions in part 4 includes radical additions, organometal addition (Heck reaction), carbene addition, and 1,3-dipolar cycloadditions.
Author | : F. Serratosa |
Publisher | : Elsevier |
Total Pages | : 418 |
Release | : 2013-10-22 |
Genre | : Science |
ISBN | : 1483290921 |
Contrary to all other books in the field of organic synthesis, this volume combines Corey's methodology, which is based on the concept of synthon and retrosynthetic analysis, with Evans' methodology based on the `Lapworth model' of alternating polarities. Using this approach, the formation of carbon-carbon bonds and the manipulation of functional groups are treated together, whereas the stereochemical aspects are considered separately. Emphasis is laid on the importance of rigid structures, whether in the starting materials, the synthetic intermediates or the transition states, as a means of controlling the stereochemistry of the organic compounds. Enclosed with the book is a copy of a miniprogram (CHAOS) for an IBM PC, or fully compatible computers, which is an interactive program, affording the beginner a fast and easy way of learning, exploring and looking for new synthetic schemes of molecules of moderate complexity. As a textbook on organic synthesis, this volume will be of immense value at university level.
Author | : Thomas Wirth |
Publisher | : John Wiley & Sons |
Total Pages | : 441 |
Release | : 2012-01-09 |
Genre | : Science |
ISBN | : 3527641955 |
Selenium-based methods in synthetic chemistry have developed rapidly over the past years and are now offering highly useful tools for organic synthesis. Filling the gap for a comprehensive handbook and ready reference, this book covers all modern developments within the field, including biochemical aspects. The chemistry chapters are organized according to the different reactivities of various selenium compounds and reagents, with each chapter dealing with a special reaction type. Also includes a table with 77Se NMR shifts to aid in practical problems. From the Contents: * Electrophilic and Nucleophilic Selenium * Selenium Compounds in Radical Reactions * Selenium-Stabilized Carbanions * Selenium Compounds with Valency Higher than Two * Selenocarbonyls * Selenoxide Elimination and [2,3]-Sigmatropic Rearrangement * Selenium Compounds as Ligands and Catalysts * Biological and Biochemical Aspects of Selenium Compounds
Author | : Kenneth K. Laali |
Publisher | : |
Total Pages | : 554 |
Release | : 2007 |
Genre | : Language Arts & Disciplines |
ISBN | : |
Inspired by a high-caliber symposium organized by the volume editor, held at Pacifichem-05 in Hawaii, leading experts and active researchers in the field report on their recent studies in the carbocation/onium ion field, emphasizing stable ion generation and NMR studies, synthetic/preparative, as well as computational work.
Author | : Alan R. Katritzky |
Publisher | : Elsevier |
Total Pages | : 1474 |
Release | : 1995-12-29 |
Genre | : Science |
ISBN | : 9780080423234 |