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| Author | : K. Schofield |
| Publisher | : CUP Archive |
| Total Pages | : 428 |
| Release | : 1976-06-24 |
| Genre | : Science |
| ISBN | : 9780521205191 |
This 1976 volume sets out in detail the structure and properties of azoles and their derivatives.
| Author | : K. Schofield |
| Publisher | : Springer |
| Total Pages | : 439 |
| Release | : 2013-12-18 |
| Genre | : Science |
| ISBN | : 1489958924 |
| Author | : Tadeusz Marek Krygowski |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 355 |
| Release | : 2009-01-30 |
| Genre | : Science |
| ISBN | : 3540683291 |
Heterocyclic chemistry is the biggest branch of chemistry covering two-thirds of the chemical literature. Aromaticity in Heterocyclic Compounds covers hot topics of frontier research summarized by reputed scientists in the field.
| Author | : Salo Gronowitz |
| Publisher | : Elsevier |
| Total Pages | : 991 |
| Release | : 2004-05-12 |
| Genre | : Science |
| ISBN | : 0080519229 |
There is a vast and often bewildering array of synthetic methods and reagents available to organic chemists today. The Best Synthetic Methods series allows any scientist who is interested in the chemical transformations of molecules to choose between all the alternatives and assess their real advantages and limitations. With the emphasis on laboratory use, these volumes represent a comprehensive and practical guide to modern synthetic organic chemistry. This book is the product of the authors many years practical experience and reading of the original literature. It contains a valuable distillation and critical evaluation of the Best Synthetic Methods for the formation and reaction of thiophenes (five membered heterocycles containing a ring sulfur) or polymers containing a thiophene functionality (thienyls). A brief review of each area is provided, but the emphasis in all cases is on describing efficient practical methods to effect the transformations described. The reader can therefore use this book to rapidly review and select the best methods of performing a synthetic conversion to create or modify a specifically substituted thiophene. Although this book contains many references to the original literature, the large number of experimental recipes enables the user to prepare a thiophene derivative without access to the original literature. These features make the handbook especially useful for physicists working in material sciences and organic/pharmaceutical chemists, who rapidly want to find out the availability of (or how to make) a specific thiophene. - Contains a systematic description and critical evaluation of the best methods for preparation of thiophenes and polymers containing thiophenes - Rapid location of methods achieved by systematic division of substituents following the periodic table - All chapters are richly illustrated by detailed experimental proceedures for the synthesis of five membered heterocycles containing sulfur
| Author | : Surya K. De |
| Publisher | : John Wiley & Sons |
| Total Pages | : 856 |
| Release | : 2021-03-08 |
| Genre | : Science |
| ISBN | : 3527347852 |
An indispensable guide for all synthetic chemists who want to learn about the most relevant reactions and reagents employed to synthesize important heterocycles and drugs! The synthesis of natural products, bioactive compounds, pharmaceuticals, and drugs is of fundamental interest in modern organic chemistry. New reagents and reaction methods towards these molecules are being constantly developed. By understanding the mechanisms involved and scope and limitations of each reaction applied, organic chemists can further improve existing reaction protocols and develop novel efficient synthetic routes towards frequently used drugs, such as Aspirin or Penicillin. Applied Organic Chemistry provides a summary of important (name) reactions and reagents applied in modern organic chemistry and drug synthesis. It covers rearrangement, condensation, olefination, metathesis, aromatic electrophilic substitutions, Pd-catalyzed C-C bond forming reactions, multi-component reactions, as well as oxidations and reductions. Each chapter is clearly structured, providing valuable information on reaction details, step-by-step mechanism, experimental procedures, applications, and (patent) references. By providing mechanistic information and representative experimental procedures, this book is an indispensable guide for researchers and professionals in organic chemistry, natural product synthesis, pharmaceutical, and medicinal chemistry, as well as post-graduates preparing themselves for a job in the pharmaceutical industry. Hot Topic: Reviews important classes of organic reactions (incl. name reactions) and reagents in medicinal chemistry. Useful: Provides information on reaction details, common reagents, and functional group transformations used to synthesize natural products, bioactive compounds, drugs, and pharmaceuticals, e.g. Aspirin, Penicillin. Unique: For every reaction the mechanism is explained step by step, and representative experimental procedures are given, unlike most books in this area. User-friendly: Chapters are clearly structured making it easy for the reader to compare different reactions. Applied Organic Chemistry is an indispensable guide for researchers and professionals in organic chemistry, natural product synthesis, pharmaceutical, and medicinal chemistry, as well as post-graduates preparing themselves for a job in the pharmaceutical industry.
| Author | : John A. Joule |
| Publisher | : John Wiley & Sons |
| Total Pages | : 332 |
| Release | : 2012-08-06 |
| Genre | : Science |
| ISBN | : 1118380193 |
This expanded second edition provides a concise overview of the main principles and reactions of heterocyclic chemistry for undergraduate students studying chemistry and related courses. Using a successful and student-friendly "at a glance" approach, this book helps the student grasp the essence of heterocyclic chemistry, ensuring that they can confidently use that knowledge when required. The chapters are thoroughly revised and updated with references to books and reviews; extra examples and student exercises with answers online; and color diagrams that emphasize exactly what is happening in the reaction chemistry depicted.
| Author | : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans |
| Publisher | : World Health Organization |
| Total Pages | : 364 |
| Release | : 2013 |
| Genre | : Medical |
| ISBN | : |
This volume of the IARC Monographs provides evaluations of the carcinogenicity of bitumens and their emissions, the N-heterocyclic polycyclic aromatic hydrocarbons benz[a]acridine, benz[c]acridine, dibenz[a,h]acridine, dibenz[a,j]acridine, dibenz[c,h]acridine, carbazole and 7H-dibenzo[c,g]carbazole, as well as the S-hetrocyclic polycyclic aromatic hydrocarbons benzo[b]naphtho[2,1-d]thiophene and dibenzothiophene. Bitumens are produced by distillation of crude oil during petroleum refining, and also occur naturally. Bitumens can be divided into six broad classes, according to their physical properties and specifications required for different applications. The major use (about 80%) of bitumens is for road paving; other uses include roofing, waterproofing, sealing and painting. The term "bitumen" should not be confused with "asphalt", which refers to the mixture of bitumen (4-10% by weight), small stones, sand and filler used for road paving. Bitumens are complex mixtures that contain a large number of organic chemical compounds. Application of bitumens may generate emissions (fumes and vapours) that may contain, among volatile and non-volatile compounds, a number of known or probable carcinogens. An IARC Monographs Working Group reviewed epidemiological evidence, animal bioassays, and mechanistic and other relevant data to reach conclusions as to the carcinogenic hazard to humans of various occupations that entail exposure to bitumens and bitumen emissions, including road paving, roofing, and application of mastic asphalt, and to various heterocyclic polycyclic aromatic compounds.
| Author | : Michael B. Smith |
| Publisher | : John Wiley & Sons |
| Total Pages | : 2379 |
| Release | : 2007-01-29 |
| Genre | : Science |
| ISBN | : 0470084944 |
The Sixth Edition of a classic in organic chemistry continues its tradition of excellence Now in its sixth edition, March's Advanced Organic Chemistry remains the gold standard in organic chemistry. Throughout its six editions, students and chemists from around the world have relied on it as an essential resource for planning and executing synthetic reactions. The Sixth Edition brings the text completely current with the most recent organic reactions. In addition, the references have been updated to enable readers to find the latest primary and review literature with ease. New features include: More than 25,000 references to the literature to facilitate further research Revised mechanisms, where required, that explain concepts in clear modern terms Revisions and updates to each chapter to bring them all fully up to date with the latest reactions and discoveries A revised Appendix B to facilitate correlating chapter sections with synthetic transformations
| Author | : Kristian Nylund |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2010 |
| Genre | : Heterocyclic compounds |
| ISBN | : 9781608763689 |
Heterocyclic compounds are organic compounds containing at least one atom of carbon, and at least one element other than carbon, such as sulphur, oxygen or nitrogen within a ring structure. These structures may comprise either simple aromatic rings or non-aromatic rings. Some examples are pyridine (C5H5N), pyrimidine (C4H4N2) and dioxane (C4H8O2). Many heterocyclic compounds, including some amines, are carcinogenic. This book details the proposed mechanisms of Gewald-like reactions and the wide scope of substituted 2-aminothiophenes for real life applications. Literary information about synthesis methods, structure, physical-chemical and biological properties is summarised, and also information about conversion of adamantyl-1 and adamantyl-2 imidazole and benzimidazole derivatives is given. In addition, 3-acetylindole derivatives have been in the centre of attention of researchers over many years due to the high practical value of these compounds. This book presents a survey of the literature on 3-acetylindoles chemistry and provides useful and up-to-date data for medicinal chemists.
| Author | : François Jérôme |
| Publisher | : John Wiley & Sons |
| Total Pages | : 183 |
| Release | : 2017-06-29 |
| Genre | : Science |
| ISBN | : 1119065445 |
A multidisciplinary overview of bio-derived solvent applications, life cycle analysis, and strategies required for industrial commercialization This book provides the first and only comprehensive review of the state-of-the-science in bio-derived solvents. Drawing on their own pioneering work in the field, as well as an exhaustive survey of the world literature on the subject, the authors cover all the bases—from bio-derived solvent applications to life cycle analysis to strategies for industrial commercialization—for researchers and professional chemists working across a range of industries. In the increasingly critical area of sustainable chemistry, the search for new and better green solvents has become a top priority. Thanks to their renewability, biodegradability and low toxicity, as well as their potential to promote advantageous organic reactions, green solvents offer the promise of significantly reducing the pernicious effects of chemical processes on human health and the environment. Following an overview of the current solvents markets and the challenges and opportunities presented by bio-derived solvents, a series of dedicated chapters cover all significant classes of solvent arranged by origin and/or chemical structure. Throughout, real-world examples are used to help demonstrate the various advantages, drawbacks, and limitations of each class of solvent. Topics covered include: The commercial potential of various renewably sourced solvents, such as glycerol The various advantages and disadvantages of bio-derived versus petroleum-based solvents Renewably-sourced and waste-derived solvents in the design of eco-efficient processes Life cycle assessment and predictive methods for bio-based solvents Industrial and commercial viability of bio-based solvents now and in the years ahead Potential and limitations of methodologies involving bio-derived solvents New developments and emerging trends in the field and the shape of things to come Considering the vast potential for new and better products suggested by recent developments in this exciting field, Bio-Based Solvents will be a welcome resource among students and researchers in catalysis, organic synthesis, electrochemistry, and pharmaceuticals, as well as industrial chemists involved in manufacturing processes and formulation, and policy makers.
