Regulation of Tissue Oxygenation, Second Edition

Regulation of Tissue Oxygenation, Second Edition
Author: Roland N. Pittman
Publisher: Biota Publishing
Total Pages: 117
Release: 2016-08-18
Genre: Medical
ISBN: 1615047212

This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Heart and Blood

Heart and Blood
Author: Richard Nelson
Publisher: Vintage
Total Pages: 428
Release: 1998-09-29
Genre: Nature
ISBN:

Examines the physiology of deer, and describes how they have had to adapt to man's encroachment on their natural environments in varied parts of the United States.

Heart's Blood

Heart's Blood
Author: Juliet Marillier
Publisher: Penguin
Total Pages: 381
Release: 2009-11-03
Genre: Fiction
ISBN: 1101149248

National bestselling author Juliet Marillier revisits the classic fairy tale of Beauty and the Beast in this “engaging Gaelic fantasy romance staring two fascinating reluctant souls”(Genre Go Round Reviews). Whistling Tor is a place of secrets, a mysterious, wooded hill housing the crumbling fortress belonging to Anluan—a chieftain whose name is spoken throughout the region in tones of revulsion and bitterness. A curse lies over Anluan’s family and his people, and the woods themselves hold a perilous force whose every whisper threatens doom. Then the young scribe Caitrin appears in Anluan’s garden, admiring the rare plant known as heart’s blood. Retained to sort through entangled family documents, Caitrin brings about unexpected changes in the household, casting a hopeful light against the despairing shadows. But even as Caitrin brings solace to Anluan, and the promise of something more between them, he remains in thrall to the darkness surrounding Whistling Tor. To free Anluan’s burdened soul, Caitrin must unravel the web of sorcery woven by his ancestors before it claims his life—and their love...

Regulation of Coronary Blood Flow

Regulation of Coronary Blood Flow
Author: Michitoshi Inoue
Publisher: Springer Science & Business Media
Total Pages: 330
Release: 2013-11-09
Genre: Medical
ISBN: 4431683674

Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.

Hematology

Hematology
Author: Ronald Hoffman
Publisher:
Total Pages: 2821
Release: 2005
Genre: Blood
ISBN: 9780443066283

Control of Cardiac Output

Control of Cardiac Output
Author: David Young
Publisher: Biota Publishing
Total Pages: 110
Release: 2010-01-01
Genre: Medical
ISBN: 1615040226

Although cardiac output is measured as the flow of blood from the left ventricle into the aorta, the system that controls cardiac output includes many other components besides the heart itself. The heart’s rate of output cannot exceed the rate of venous return to it, and therefore, the factors governing venous return are primarily responsible for control of output from the heart. Venous return is affected by its pressure gradient and resistance to flow throughout the vascular system. The pressure gradient for venous return is a function of several factors including the blood volume flowing through the system, the unstressed vascular volume of the circulatory system, its capacitance, mean systemic pressure, and right atrial pressure. Resistance to venous return is the sum of total vascular resistance from the aortic valve to the right atrium. The sympathetic nervous system and vasoactive circulating hormones affect short-term resistance, whereas local tissue blood flow autoregulatory mechanisms are the dominant determinants of long-term resistance to venous return. The strength of contraction of the heart responds to changes in atrial pressure driven by changes in venous return, with small changes in atrial pressure eliciting large changes in strength of contraction, as described by the Frank–Starling mechanism. In addition, the autonomic nervous system input to the heart alters myocardial pumping ability in response to cardiovascular challenges. The function of the cardiovascular system is strongly affected by the operation of the renal sodium excretion–body fluid volume–arterial pressure negative feedback system that maintains arterial blood pressure at a controlled value over long periods. The intent of this volume is to integrate the basic knowledge of these cardiovascular system components into an understanding of cardiac output regulation. Table of Contents: Introduction / Venous Return / Cardiac Function / Integrated Analysis of Cardiac Output Control / Analysis of Cardiac Output Regulation by Computer Simulation / Analysis of Cardiac Output Control in Response to Challenges / Conclusion / References / Author Biography

A Heart of Blood and Ashes

A Heart of Blood and Ashes
Author: Milla Vane
Publisher: Penguin
Total Pages: 562
Release: 2020-02-04
Genre: Fiction
ISBN: 0425255077

A generation past, the western realms were embroiled in endless war. Then the Destroyer came. From the blood and ashes he left behind, a tenuous alliance rose between the barbarian riders of Parsathe and the walled kingdoms of the south. That alliance is all that stands against the return of an ancient evil—until the barbarian king and queen are slain in an act of bloody betrayal. Though forbidden by the alliance council to kill the corrupt king responsible for his parents’ murders, Maddek vows to avenge them, even if it costs him the Parsathean crown. But when he learns it was the king’s daughter who lured his parents to their deaths, the barbarian warrior is determined to make her pay. Yet the woman Maddek captures is not what he expected. Though the last in a line of legendary warrior-queens, Yvenne is small and weak, and the sharpest weapons she wields are her mind and her tongue. Even more surprising is the marriage she proposes to unite them in their goals and to claim their thrones—because her desire for vengeance against her father burns even hotter than his own…

Circulation of the Blood

Circulation of the Blood
Author: Alfred P. Fishman
Publisher: Springer
Total Pages: 871
Release: 2013-05-26
Genre: Medical
ISBN: 1461475465

Capturing the real spirit of creativity in physiology, this book explores the personal elements involved in scientific discovery. Circulation of the Blood is the story of the people and achievements that have changed the way we've come to view the human body. The authors, renowned for their extensive experience in the field, examine the heritage of creative genius involved in physiology and trace the historical development of ideas relating to various aspects of circulation of the blood. Their comprehensive coverage goes from the early discoveries of the Greeks and Romans up to modern times.

Heart and Toxins

Heart and Toxins
Author: Dr. Meenakshisundaram Sundaram Ramachandran
Publisher: Elsevier
Total Pages: 668
Release: 2014-08-12
Genre: Science
ISBN: 0124165990

The Heart and Toxins brings together global experts to provide the latest information and clinical trials that make the connection between genetic susceptibility, gene expression, and environmental factors in cardiovascular diseases. This unique reference, edited by renowned cardiologist Meenakshi Sundaram Ramachandran, solves the problem of managing multiple clinical cases of cardiovascular toxicity. It allows connections to be made between research, diagnosis, and treatment to avoid higher morbidity and mortality rates as a result of cardiovascular toxicity. - Structured to bring together exploration into the epidemiology, molecular mechanism, pathogenesis, environmental factors and management in cardiovascular toxins - Included various topics on cardiovascular toxins such as plant, chemical, animal, nanomaterial and marine biology induced cardiac damage – which are new ideas discussed in detail - Comprehensive chapters on the cardiovascular toxicity from drugs, radiotherapy and radiological imaging - Enables you to manage multiple clinical cases of cardiovascular toxicity - Outlined conclusions at the end of each chapter providing "key learning points to help you organize the chapter's details without losing insight