This exposure assessment provides a range of possible human health risk at two locations due to groundwater transport from the Faultless underground nuclear test. These locations correspond to the boundary of the land under DOE control (where no wells currently exist) and the closest existing well (Six Mile Well). The range in excess risk is within the EPA goal for excess risk due to environmental contaminants (10−6) at Six Mile Well. Calculations considering high spatial variability in hydraulic properties and/or high uncertainty in the mean groundwater velocity are also within the EPA goal. At the DOE boundary, the range in excess risk exceeds the EPA goal, regardless of the values of spatial variability and uncertainty. The range in values of excess risk can be reduced with additional field data from the site; however, incorporation of additional data, which would likely be obtained at great expense, is unlikely to result in significant refinement of the results.