Glycoscience: Biology and Medicine

Glycoscience: Biology and Medicine
Author: Tamao Endo
Publisher: Springer
Total Pages:
Release: 2021-01-14
Genre: Science
ISBN: 9784431548362

The aim of the book is to provide a succinct overview of the current status of glycoscience from both basic biological and medical points of view and to propose future directions, in order to facilitate further integrations of glycoscience with other fields in biological and medical studies. Glycans (carbohydrate oligomers) are the so-called “building blocks” of carbohydrates, nucleic acids, proteins and lipids and play major roles in many biological phenomena as well as in various pathophysiological processes. However, this area of glycoscience has been neglected from the research community because glycan structures are very complex and functionally diverse and as compared to proteins and nucleic acids simple tools for the amplification, sequencing and auto-synthesis of glycans are not available. Many scientists in other fields of research have now realized that glycosylation, i.e. the addition of glycans to a protein backbone, is the most abundant post translational modification reactions and is an important field of research and sometimes they require a glycobiology and/or glycochemistry approach to be used. It is still difficult, however, for non-expert researchers to use these techniques. This book will provide numerous but simple overviews of current topics and protocols for the experiments. The book is aimed at university students and above, including non-experts in the field of glycoscience.

Comprehensive Glycoscience

Comprehensive Glycoscience
Author: G.-J. Boons
Publisher: Elsevier Science
Total Pages: 3600
Release: 2007-08-21
Genre: Science
ISBN: 9780444527462

Carbohydrates are an important part of life and are present in bacteria, fungi, viruses, yeast, plants, animals and humans. The rapid expansion of chemistry and glycobiology over the last few years has provided many new, imaginative and efficient techniques which provide further insight into the structures and biological interactions of carbohydrates and glycostructures. Comprehensive Glycoscience has a very broad scope and will appeal to a wide audience as it explores the interactions between biology, chemistry and molecular biology towards understanding, synthesising and developing glycoproteins, glycolipids, proteoglyans and polysaccharides, which are important molecules in nature for controlling health and disease and food and feed. Glycocompounds reviewed include: oligosaccharides, polysaccharides, glycoproteins, glycolipids, glycoconjugates, lectins, cellulose, pectins and starch. Topics covered include: spectroscopy, nomenclature, structures, synthesis, biosynthesis, molecular interactions, degradation, biochemistry, glycobiology, glycotherapeutics and diseases. Combines multiple aspects of glycoscience in one comprehensive work Documents the new and rapid expansion of carbohydrate chemistry and glycobiology over the last few years Highlights the many new, imaginative and efficient techniques for providing insights into carbohydrates and glycostructures

Glycoscience

Glycoscience
Author: Bertram O. Fraser-Reid
Publisher: Springer
Total Pages: 986
Release: 2001-12-01
Genre: Science
ISBN: 9783540677659

Glycostructures play a highly diverse and crucial role in a myriad of organisms and important systems in biology, physiology, medicine, bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and the chemistry behind them, but many facts still remain undiscovered. "All roads lead to carbohydrates ... we cannot do without them." (K.C. Nicolaou). Presently the field is experiencing a "quantum jump". Therefore the editors have drawn together in this three volume set the complete and up-to-date information on glycostructures, their chemistry and chemical biology, and present them in the form of a comprehensive and strictly systematic survey. The texts are furnished by 2.670 figures, chemical structures and reaction schemes (including more than 12.000 individual chemical reactions), and more than 9.000 references.

Introduction to Glycobiology

Introduction to Glycobiology
Author: Maureen E. Taylor
Publisher: Oxford University Press, USA
Total Pages: 305
Release: 2011-04-21
Genre: Medical
ISBN: 0199569118

Introduction to Glycobiology reveals the true impact of the sugars on biological systems, explaining their function at the molecular, cellular, and organismal level and their clinical relevance.

Glycobiology and Human Diseases

Glycobiology and Human Diseases
Author: Gherman Wiederschain
Publisher: CRC Press
Total Pages: 334
Release: 2016-02-22
Genre: Medical
ISBN: 1498709192

This book discusses glycobiology and various forms of human diseases. Topics covered include immunoglobulins, inflammation and glycosylation, the role and therapeutic significance of natural anti-glycan antibodies in malignancies and in normal and aberrant pregnancy, identifying urinary glycans as a possible method for the diagnosis of lysosomal st

Glycoscience: Basic Science to Applications

Glycoscience: Basic Science to Applications
Author: Naoyuki Taniguchi
Publisher: Springer Nature
Total Pages: 405
Release: 2019-09-12
Genre: Medical
ISBN: 9811358567

This book presents the state of the art in glycoscience and proposes a road map for the coming decade, focusing on the potential of glycoscience research to shed light on important basic science issues and give rise to exciting new applications, especially in the field of diagnosis and therapeutics. Individual sections offer in-depth coverage of various topics relating to glycans and biopharmaceuticals, glycans in medical science and medicine, glycan technologies, glycans in food and nutrients, and glycan-related materials and their uses. In addition, the book presents an exemplary training course on glycomics and highlights educational and analytical web resources, and also includes glossaries and boxes summarizing key facts to ensure ease of understanding for non-expert readers and students. Written by more than 150 active participants in the Japan Consortium for Glycobiology and Glycotechnology (JCGG), whose goal is to promote the development of interdisciplinary glycoscience and establish a global network in the field, it is a valuable resource for students, postdocs, and researchers in the life sciences as well as for stakeholders and professionals in government, funding agencies and industry.

Glycosciences

Glycosciences
Author: Hans-Joachim Gabius
Publisher: John Wiley & Sons
Total Pages: 663
Release: 2008-09-26
Genre: Science
ISBN: 3527614729

A comprehensive survey of the topic, ranging from basic molecular research to clinical applications. Critical reviews by leading experts in each field summarize the state of knowledge and discuss the anticipated benefits of novel approaches and strategies. These include the impact of modern analysis techniques on glycobiology, the use of synthetic neoglycoproteins, or the clinical consequences of new insights into the physiological role of lectins and glycoconjugates in pathology, oncology, immunity, neuroscience and reproduction medicine. Throughout, the aim is to separate realistic applications from mere hopes.

Glycobiology and Medicine

Glycobiology and Medicine
Author: John S. Axford
Publisher: Springer Science & Business Media
Total Pages: 306
Release: 2003
Genre: Medical
ISBN: 9780306477829

This text contains the Proceedings of the Sixth Jenner Glycobiology and Medicine Symposium, held 14-17 September, 2002, in Seillac, France. It highlights the most up-to-date developments in glycoimmunology, including glycosylation-dependent bacterial and viral infections, lectin and proteoglycan-dependent interactions in leukocyte homing processes to lymphoid tissues and inflamed tissues, congenital defects in glycosylation of glycoproteins and glycolipids, and the role of carbohydrates in tumour development and neuropathology, including Creutzfeldt-Jakob disease.

Experimental Glycoscience

Experimental Glycoscience
Author: Naoyuki Taniguchi
Publisher: Springer Science & Business Media
Total Pages: 255
Release: 2009-03-08
Genre: Science
ISBN: 4431779248

The aim of this book is to provide experimental protocols covering many aspects of glycobiology, glycotechnology, and chemistry: biochemistry, molecular and cellular biology, genetics, physiology, and medicine. The protocols are all self-contained descriptions of the equipment and reagents needed, followed by details of the experimental procedure. In the post-genomic era, glycobiology is coming of age because more than half of proteins are glycosylated and the importance of sugar chains in various fields of life science research cannot be disregarded. Many scientists had not entered this area because glycobiology and glycoscience used to be considered difficult fields. This book, therefore, is presented much like a cookbook which can help scientists in fields other than glycobiology and glycoscience carry out research more easily.

Glycoscience: Chemistry and Chemical Biology I–III

Glycoscience: Chemistry and Chemical Biology I–III
Author: Bertram O. Fraser-Reid
Publisher: Springer Science & Business Media
Total Pages: 2817
Release: 2012-12-06
Genre: Science
ISBN: 3642568742

Glycostructures play a highly diverse and crucial role in a myriad of organisms and systems in biology, physiology, medicine, and bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and chemistry behind them. In this set the editors present up-to-date information on glycostructures, their chemistry and chemical biology, in the form of a comprehensive survey. The text is accompanied by over 2000 figures, chemical structures and reaction schemes and more than 9000 references. The accompanying CD-ROM enables, besides text searches, searches for structures, schemes, and other information.