Glioblastoma, Part I: Surgical Management and Adjuncts, An Issue of Neurosurgery Clinics of North America, E-Book

Glioblastoma, Part I: Surgical Management and Adjuncts, An Issue of Neurosurgery Clinics of North America, E-Book
Author: Michael A Vogelbaum
Publisher: Elsevier Health Sciences
Total Pages: 169
Release: 2020-12-04
Genre: Medical
ISBN: 032379095X

This issue of Neurosurgery Clinics, guest edited by Dr. Michael A. Vogelbaum, is devoted to Glioblastoma, Part I: Surgical Management and Adjuncts. This is one of four issues selected each year by the series Consulting Editors, Russell R. Lonser and Daniel K. Resnick. Articles in this issue include: Perioperative Management of Patients with Glioblastoma, Role of Resection in Glioblastoma Management, Advancing Imaging to Enhance Surgery, Intraoperative Imaging for High-Grade Glioma Surgery, Use of Intraoperative Fluorophores, Extent of Resection of Glioblastoma, Functional Mapping for Glioma Surgery: Preoperative Mapping Tools, Functional Mapping for Glioma Surgery: Intraoperative Mapping Tools, Surgical Adjuncts for Glioblastoma, Window of Opportunity Clinical Trials to Evaluate Novel Therapies for Brain Tumors, Stereotactic Laser Ablation of Glioblastoma, Radiosurgery for Glioblastoma, Challenges Associated with Reoperation in Patients with Glioma, and Surgery for Glioblastoma in Elderly Patients.

Glioblastoma, Part I: Surgical Management and Adjuncts, an Issue of Neurosurgery Clinics of North America

Glioblastoma, Part I: Surgical Management and Adjuncts, an Issue of Neurosurgery Clinics of North America
Author: Michael A Vogelbaum
Publisher: Elsevier
Total Pages: 240
Release: 2021-02-12
Genre: Medical
ISBN: 9780323790949

This issue of Neurosurgery Clinics, guest edited by Dr. Michael A. Vogelbaum, is devoted to Glioblastoma, Part I: Surgical Management and Adjuncts. This is one of four issues selected each year by the series Consulting Editors, Russell R. Lonser and Daniel K. Resnick. Articles in this issue include: Perioperative Management of Patients with Glioblastoma, Role of Resection in Glioblastoma Management, Advancing Imaging to Enhance Surgery, Intraoperative Imaging for High-Grade Glioma Surgery, Use of Intraoperative Fluorophores, Extent of Resection of Glioblastoma, Functional Mapping for Glioma Surgery: Preoperative Mapping Tools, Functional Mapping for Glioma Surgery: Intraoperative Mapping Tools, Surgical Adjuncts for Glioblastoma, Window of Opportunity Clinical Trials to Evaluate Novel Therapies for Brain Tumors, Stereotactic Laser Ablation of Glioblastoma, Radiosurgery for Glioblastoma, Challenges Associated with Reoperation in Patients with Glioma, and Surgery for Glioblastoma in Elderly Patients.

Modern Management of High Grade Glioma, Part I, An Issue of Neurosurgery Clinics

Modern Management of High Grade Glioma, Part I, An Issue of Neurosurgery Clinics
Author: Isaac Yang
Publisher: Elsevier Health Sciences
Total Pages: 174
Release: 2012-04-28
Genre: Medical
ISBN: 1455744182

Standard therapy for high grade glioma is a topic that is evolving, timely, and relevant. Guest Editors Isaac Yang, MD and Seunggu Han, MD have assembled a group of experts to highlight the latest updates on various forms of management of high grade glioma. Some of the articles included in this issue focus on Extent of Resection for Glioblastoma; Role of adjuvant radiation therapy; Survival benefit of the Temozolomide protocol; Alternative chemotherapeutic agents; The role of avastin; Radiology; Pseuodprogression and Treatment effect; Pathology; Medical Management; Management of insular gliomas; Use of motor mapping; GBM treatment with clinical trials for surgical resection; Clinical trials with immunotherapy; Clinical trials for small molecule inhibitors; Future role of CED for GBM treatment; Application of a vault nanoparticle therapy for GBM therapy; Management of high grade gliomas in pediatric populations; Targeting Glioma Stem Like Cells with a focus on CD 133; and Potential Role for STAT3 inhibitors in glioblastoma.

Glioblastoma, Part II: Molecular Targets and Clinical Trials, An Issue of Neurosurgery Clinics of North America

Glioblastoma, Part II: Molecular Targets and Clinical Trials, An Issue of Neurosurgery Clinics of North America
Author: Linda M. Liau
Publisher: Elsevier Health Sciences
Total Pages: 208
Release: 2021-04-08
Genre: Medical
ISBN: 0323813062

This issue of Neurosurgery Clinics, guest edited by Dr. Linda M. Liau, is dedicated to Glioblastoma: Molecular and Clinical Trials. This issue is one of four selected each year by the series consulting editors, Drs. Russell R. Lonser and Daniel K. Resnick. Topics will include—but are not limited to—Pathology & Molecular Markers, Cellular States & Genetic Diversity in Glioblastoma, Mismatch Repair in Glioblastoma Resistance, Genetic Susceptibility in Brain Cancer, Pediatric Gliomas: Molecular Landscape & Emerging Targets, Molecularly Targeted Clinical Trials, Novel Radiation Sensitizers, Immunotherapy Checkpoint Inhibitors, Brain Tumor Vaccines, CAR T Cells, Oncolytic Virotherapy, Targeting Cancer Stem Cells, Therapeutic Delivery to CNS, Theranostics: Dual Modality PET Tracers, and Neuroimaging & Novel Response Assessments.

Epilepsy Surgery: The Network Approach, An Issue of Neurosurgery Clinics of North America, E-Book

Epilepsy Surgery: The Network Approach, An Issue of Neurosurgery Clinics of North America, E-Book
Author: Mark Richardson
Publisher: Elsevier Health Sciences
Total Pages: 240
Release: 2020-07-28
Genre: Medical
ISBN: 0323756999

This issue of Neurosurgery Clinics, guest edited by Dr. R. Mark Richardson and Dr. Vasileios Kokkinos, will focus on Epilepsy Surgery: The Network Approach. This issue is one of four selected each year by our series consulting editors, Dr. Russell R. Lonser and Dr. Daniel K. Resnick. Topics discussed in this issue will include: History of the network approach in epilepsy surgery, Networks in temporal lobe epilepsy, Networks in frontal lobe epilepsy, Networks in parietal and occipital lobe epilepsy, Structures facilitating epileptogenic network formation, Extracranial interictal and ictal EEG in sEEG planning, Ictal semiology as a tool for sEEG planning, The significance of MRI lesions in sEEG planning, Functional networks in epilepsy presurgical evaluation, Automation advances in sEEG planning, Interpretation of the intracranial sEEG signal, Electrical cortical stimulation, Epileptogenic index, Modeling the epileptogenic network, Machine learning in epilepsy surgery evaluations, Neuromodulation of epilepsy networks, and Decision-making in epilepsy surgery.

Update on Motion Preservation Technologies, An Issue of Neurosurgery Clinics of North America, E-Book

Update on Motion Preservation Technologies, An Issue of Neurosurgery Clinics of North America, E-Book
Author: Domagoj Coric
Publisher: Elsevier Health Sciences
Total Pages: 129
Release: 2021-09-22
Genre: Medical
ISBN: 0323810551

This issue of Neurosurgery Clinics, guest edited by Dr. Domagoj Coric, provides an Update on Motion Preservation Technologies. This issue is one of four selected each year by our series consulting editors, Drs. Russell R. Lonser and Daniel K. Resnick. This issue discusses state-of-the-art indications, technique, devices, complications and evidence basis for motion preserving technologies in the cervical and lumbar spines. Topics covered in this issue will include: Cervical Total Disc Replacement: Indications and Technique, Cervical Total Disc Replacement: Off-label and Expanded Indications, Cervical Total Disc Replacement: FDA-approved Devices, Cervical Total Disc Replacement: Novel Devices, Cervical Spine Surgery: Arthroplasty versus Fusion versus Posterior Foraminotomy, Cervical Total Disc Replacement: Complications and Complication Avoidance, Cervical Total Disc Replacement: Long-term Outcomes, Biomechanics of Cervical Arthroplasty Devices, Adjacent-level Disease following Spinal Arthroplasty, Lumbar Total Disc Replacement: Current Usage, and Posterior Lumbar Facet Replacement and Arthroplasty.

Current State of the Art in Spinal Trauma, An Issue of Neurosurgery Clinics of North America, E-Book

Current State of the Art in Spinal Trauma, An Issue of Neurosurgery Clinics of North America, E-Book
Author: John Hurlbert
Publisher: Elsevier Health Sciences
Total Pages: 137
Release: 2021-06-08
Genre: Medical
ISBN: 0323810594

This issue of Neurosurgery Clinics, guest edited by Dr. John Hurlbert, is devoted to Current State of the Art in Spinal Cord Injury. This is one of four issues selected each year by the series Consulting Editors, Russell R. Lonser and Daniel K. Resnick. Articles in this issue are dedicated to basics of spinal cord injury and emerging therapy and include topics such as: Pathophysiology of spinal cord injury, Natural history of spinal cord injury, Diagnostic imaging in spinal cord injury, Spinal cord injury clinical assessment tools, Spinal cord injury management on the front line, Central Cord Syndrome redefined, Compartment Syndrome, Hypothermia, Pharmaceutical, Regeneration, and Neural interfacing and modulation.

Intracranial Gliomas Part I - Surgery

Intracranial Gliomas Part I - Surgery
Author: M.F. Chernov
Publisher: Karger Medical and Scientific Publishers
Total Pages: 266
Release: 2017-12-14
Genre: Medical
ISBN: 3318060577

Aggressive surgical removal is generally considered the main initial management option for most intracranial gliomas. It often results in resolution or alleviation of neurological symptoms and signs, normalizes intracranial pressure, facilitates characterization of the neoplasm, creates optimal conditions for adjuvant therapy and neurorehabilitation, and leads to prolongation of progression-free and overall survival of patients. Leading experts in neurosurgical oncology have contributed to this volume, highlighting modern principles of surgery for both newly-diagnosed and recurrent intracranial gliomas in adult as well as pediatric patients. The first of a three-volume set, it details epidemiological aspects, defines the importance of preoperative imaging, and describes current perioperative adjuvant needs. In addition, contemporary methods of intraoperative neurophysiological monitoring, the value of brain mapping for functional preservation, tips to prevent complications, and postoperative results are presented and discussed. This book and its accompanying volumes are mainly directed at neurosurgeons, neuro-oncologists and other clinicians treating patients with brain tumors.

Low-Grade Glioma, An Issue of Neurosurgery Clinics of North America

Low-Grade Glioma, An Issue of Neurosurgery Clinics of North America
Author: Guy M. McKhann
Publisher: Elsevier Health Sciences
Total Pages:
Release: 2018-11-23
Genre: Medical
ISBN: 0323655025

This issue of Neurosurgery Clinics, guest edited by Drs. Guy McKhann and Hugues Duffau, with consulting editors Russell R. Lonser and Daniel K. Resnick, will focus on Low-Grade Glioma. Topics includes, but are not limited to, Epidemiology and Molecular Epidemiology; WHO Pathological and Molecular Classification; Molecular Pathogenesis; Glioma Cell Migration and Heterogeneity; Clinical Presentation, Natural History, and Prognosis; LGG Epilepsy; MRI, fMRI, DTI, Molecular Imaging; Brain Mapping Techniques in LGG; Surgical Adjuncts to Increase EOR iMRI, Flourescence, Raman Histology; Mapping Cognition and Emotion; Extent of Resection; EOR vs Molecular Classification; Chemotherapy Treatment and Trials; Radiotherapy Treatment and Trials; Higher Order Surgical Questions; and Building a Glioma Practice.

The Glioma Book

The Glioma Book
Author: Michael E. Sughrue
Publisher: Thieme
Total Pages: 827
Release: 2019-10-25
Genre: Medical
ISBN: 1626234450

A unique resource on glioma leverages advances and firsthand insights to enact meaningful change Glioblastoma (GBM) or glioma is an extremely aggressive and malignant brain tumor, with cell infiltration, rapid invasion, and a high frequency of relapse. The Glioma Book by neurosurgeon Michael Sughrue is a highly personal book — a culmination of two years of writing and more than 1,000 surgeries. It presents a unique viewpoint with the potential to transform the traditional paradigm that too often informs treatment of this universally fatal brain tumor. The book reinterprets the role of the cerebrum and sub-cortex, leverages scientific advances to improve cytoreduction and reduce neurological deficits, and challenges the myth of the "inoperable" glioma. This is the first step-by-step technical guide focused on aggressively resecting different types of gliomas. The book is logically organized, starting with a foundation of fundamental knowledge, then progressing to practical applications. Chapters focus on the skills necessary to perform glioma surgery, specific techniques, and systematic approaches to gliomas in different brain regions. Numerous case examples illuminate concepts introduced earlier in the book and explain how to perform these procedures About 30 high quality videos posted online provide insightful procedural guidance The role of connectomic imaging in visualizing the cerebrum, and other innovative techniques including awake brain mapping and diffusion tensor tractography Neurosurgeons who embrace the concepts in this book will realize they can change the glioma treatment paradigm. Continually improving techniques and viewing a glioma diagnosis as a battle for a patient's life, rather than an exercise in inevitable failure can impart progress in treating this devastating disease.