Current Topics in Coronary Research

Current Topics in Coronary Research
Author: Colin Bloor
Publisher: Springer Science & Business Media
Total Pages: 312
Release: 2013-03-09
Genre: Medical
ISBN: 1461590205

How can you adequately honor a man of deeds with mere words? Dr. Donald Eaton Gregg is recognized throughout the scientific world for his distinguished contributions to our knowledge of the coronary circulation, his advances in experimental instrumentation and design, his scientific integrity and his lasting influence on other investigators. His research associates over the years are now liberally scattered over the entire world. Their accomplishments and activities reflect the quality of their training in his Department of Cardiorespiratory Diseases at the Walter Reed Army Institute of Research. The positions of prestige occupied by these men attest to Dr. Gregg's ability to select and inspire men of talent, yet in his usual modest way he insists that he was only fortunate to be in the right place at the right time. Thus, at the time of Dr. Gregg's retirement as Chief of the Department of Cardiorespiratory Diseases, a position he has held since 1950, his associates thought that a scientific symposium was the most appropriate way to honor a man of his stature. Accordingly, on March 29-30, 1973 a Symposium on Current Topics in Coronary Research was held at the Walter Reed Army Institute of Research. Its objectives were to define our present state of knowl edge and, more importantly, define the basic questions requiring further experimentation in four major areas of coronary research, i. e.

Immunity in Viral and Rickettsial Diseases

Immunity in Viral and Rickettsial Diseases
Author: A. Kohn
Publisher: Springer Science & Business Media
Total Pages: 280
Release: 2012-12-06
Genre: Medical
ISBN: 1468432257

The OHOLO conferences have been convened annually as from the spring of 1956; they have covered very wide areas from different and overlapping disciplines, as can be seen from the following list: 1956 Bacterial Genetics (not published) 1957 Tissue Cultures in Virological Research (not published) 1958 Inborn and Acquired Resistance to Infection in Animals (not published) 1959 Experimental Approach to Mental Diseases (not published) 1960 Cryptobiotic Stages in Biological Systems* 1961 Virus - Cell Relationships** 1962 Biological Synthesis and Function of Nucleic Acids** 1963 Cellular Control Mechanism of Macromolecular Synthesis** 1964 Molecular Aspects of Immunology** 1965 Cell Surfaces** 1966 Chemistry and Biology of Psychotropic Agents (not published) 1967 Structure and Mode of Action of Enzymes** 1968 Growth and Differentiation of Cells in vitro** 1969 Behaviour of Animal Cells in Culture** 1970 Microbial Toxins** 1971 Interaction of Chemical Agents with Cholinergic Mechanisms** The participants at these meetings from the different scien tific institutions of Israel and from many countries, are engaged in fields of study which represent widely divergent approaches to biology. Thus, a characteristic feature of the OHOLO meetings has been their multi-disciplinary nature. These small international conferences are distinguished by the relaxed atmosphere in which they are held, with ample time for informal as weIl as formal discussions. *Published by Elsevier Publishing Co. , Amsterdam (1960). **Published by the Israel Institute for Biological Research, Ness Ziona.

The Visual System

The Visual System
Author: G. Arden
Publisher: Springer Science & Business Media
Total Pages: 330
Release: 2013-03-09
Genre: Medical
ISBN: 1468482319

The International Society for Clinical Electroretinography provides a link between scientists who are enlarging our understanding of the normal functioning of the visual pathway, and clinicians who investigate and treat visual disturbances. The chief function of the Society is to organise symposia, where, with skill born of long practice, the participants obtain the benefits of both social and scientific contact, without detriment to either. The result ing spread of information is documented both in the society's Newsletter, and by the publication of volumes such as this, the record of the 9th Symposium held at Brighton in 1971. This meeting was a joint Symposium of the ISCERG and the International Union of Physiological Sciences. The subjects covered represent merely the interests of the organisers. The biophysical studies are represented by chapters on such divers topics as the x-ray diffraction of receptor membranes and impedance properties of outer limb suspensions. Other papers deal with the problems of maintaining the retina in vitro in a physiological condition. Papers describing techniques for investigating the functional properties of the visual system shade into those which describe new aspects of human disease. In the past such serendipity has been of value as evidenced by compal-ison between this and previous volumes. In 1965 the physiological section of the Proceedings was largely devoted to a new elec trical response, the evoked potential of the visual cortex.

The Artery and the Process of Arteriosclerosis

The Artery and the Process of Arteriosclerosis
Author: Stewart Wolf
Publisher: Springer Science & Business Media
Total Pages: 322
Release: 2013-03-09
Genre: Medical
ISBN: 1468481304

The present volume contains the first half of the edited tran script of a six-day Conference, "Fundamental Data on Reactions of Vascular Tissue in Man," held April 19-25, 1970, in Lindau, West Germany. The remainder of the proceedings, dealing with the epide miologic, clinical and preventive aspects of arteriosclerosis, will be published in a second volume. The Conference was held under the auspices of the International Society of Cardiology, the International Cardiology Foundation and the European Atherosclerosis Group. The aim of the Conference was to achieve a synthesis of present knowledge concerning arterioscle rosis. Therefore, workers were brought together from several coun tries and from various disciplines that do not ordinarily intercom municate for free exchange of data and ideas. Six broad subject areas were introduced by single papers; three of them are included in this volume. In the discussion which followed each formal pres entation, the participants attempted to reconcile disparate data and interpretations and to reach .a clear identification of important areas of ignorance and of crucial questions for future research. The format of the proceedings does not follow precisely that of the Conference itself. The formal papers are included, somewhat ab breviated, and excerpts of the discussion have been gathered under a series of topics arranged in logical sequence. Therefore, the quoted statements do not necessarily appear in order or in the place in the program where they were made. Principal issues, syntheses and unanswered questions are interspersed among the topics as edi torial comments.

The Reticuloendothelial System and Immune Phenomena

The Reticuloendothelial System and Immune Phenomena
Author: N. Di Luzio
Publisher: Springer Science & Business Media
Total Pages: 446
Release: 2012-12-06
Genre: Medical
ISBN: 1468432044

This volume represents a portion of the Proceedings of the Sixth International Meeting of the Reticuloendothelial Society. There is little question that the University of Freiburg was a most appropriate choice as the site of the meeting since, in essence, the Society was founded here when Aschoff undertook his classical studies on the macrophage and discovered what may well have been the last remaining biological system. In the approximate fifty years which have elapsed since Aschoff introduced the descriptive term Reticuloendothelial System to unify those cells with the common property of phagocytosis, one finds investigative activity at the highest level in all areas of reticuloendothelial involvement. Indeed, the topics covered in the present volume would of necessity require that the common property of phagocytosis which led to the formulation of the reticuloendothelial system be modified. The common basis at the present is clearly no longer phagocytic expression, but the unifying basis of host defense. The totality of reticuloendothelial involvement in host-defense is clearly reflected by the diverse scientific backgrounds and research interests of the participants of the meeting. Remarkable advances in appreciating the involvement of the RES in maintaining the well-being of the host against a variety of endogenous and exogenous factors have been made since volume I of the Advances in Experimental Biology and Medicine on the reticulo endothelial system was published.

Purine Metabolism in Man

Purine Metabolism in Man
Author: Oded Sperling
Publisher: Springer Science & Business Media
Total Pages: 453
Release: 2013-11-11
Genre: Science
ISBN: 1475714335

Gout and urie acid lithiasis are known to have affected mankind for thousands of years. It is only recently, however, that great progress has been made in the understanding of the processes involved in purine metabolism and its disorders in man. The key enzymes active in the various pathways of purine synthesis and degradation have become known and their properties are the subject of intensive study. Major contributions to the knowledge of normal purine metabolism in man have derived from the study of inborn errors in patients with purine disorders, specifically complete and partial hypoxanthine-guanine phosphoribosyltransferase deficiency. Mutations of other enzymes involved in purine metabolism are being discovered. A great step forward has been made in the treatment of gout with the introduction of uricosuric drugs and more recently of the hypoxanthine analogue allopurinol, a synthetic xanthine oxidase inhibitor. Furthermore, the complex nature of the renal handling of urie acid excretion, although still posing difficult problems, appears to approach clari fication.

Vasopeptides

Vasopeptides
Author: N. Back
Publisher: Springer Science & Business Media
Total Pages: 495
Release: 2012-12-06
Genre: Science
ISBN: 1468474391

The dynamic state of developments within the field of the vasoactive polypeptides is reflected in the continuous series of publications appearing on this topic Thus, the proposal to con o vene another symposium only two years after the 1969 Fiesole Symposium (Plenum Press, 1970) was received enthusiastically and with high expectation. Enthusiasm was based, undoubtedly, in part on meeting together once again in the very pleasant surroundings of Florence with most gracious and enchanting hosts. The 25th International Congress on Physiological Sciences held in Munich the following week also provided the impetus for the organization of this satellite symposium on vasopeptides. However, the accelerated pace of research in the "kinin" field was the major motivating force for the symposium. It was felt necessary to inform each other of the many advances that were taking place in the varied aspects of this specialized but impor tant field o The role of kinins in both physicologic and pathologic processes still remains to be elucidated definitively. Thus, these proceedings contain new and unpublished informa tion on the chemistry, biochemistry, physicology, pharmacology, as well as pathophysiology of vasopeptides. Recent data on &tructure activity relationships of kinin analogues are complemented by a description of radioimmunoassay techniques for kinins, and studies on the site of synthesis of substrates for kinin-forming enzymes.

Sphingolipids, Sphingolipidoses and Allied Disorders

Sphingolipids, Sphingolipidoses and Allied Disorders
Author: Bruno Volk
Publisher: Springer Science & Business Media
Total Pages: 693
Release: 2013-04-17
Genre: Medical
ISBN: 1475765703

This text contains the scientific contributions to the Fourth International Symposium on Sphingolipids, Sphingo lipidoses and Allied Disorders held at the Kingsbrook Jewish Medical Center on October 25-27, 1971. These meetings were conducted under the auspices of the Isaac Albert Research Institute of the Kingsbrook Jewish Medical Center and the National Tay-Sachs and Allied Diseases Association, Inc. Four symposia, held in 1958, 1961, 1965 and 1971 were designed to gather the most relevant and innovative of the laboratory and field studies concerned with these hereditary disorders. The texts generated by these periodic meetings have mirrored the increasing absorption of the scientific community in the problems of sphingolipid metabolism. The first meeting in 1958 consisted of but twelve pre sentations, the majority emanating from local laboratories. The current sessions contain 48 scientific presentations by scientists from nine countries and demonstrate the increas ingly diversified techniques and approaches employed in the study of these diseases. Many of the authors, in exploring data on the mucopolysaccharidoses and leucodystrophies, as well as the sphingolipidoses, have given recognition to those biochemical areas held in common by these otherwise diverse disease processes. The problems of prevention and therapy of these diseases have been considered by some of the contributors. Laboratory screening procedures designed to detect carriers of the va rious lipidoses are now available and the experiences of some laboratories in this area are summarized within this volume. The prospective identification of heterozygotes may indeed become a powerful adjunct in genetic counseling.