Genomic Signal Processing
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| Author | : Ilya Shmulevich |
| Publisher | : Princeton University Press |
| Total Pages | : 314 |
| Release | : 2014-09-08 |
| Genre | : Science |
| ISBN | : 1400865263 |
Genomic signal processing (GSP) can be defined as the analysis, processing, and use of genomic signals to gain biological knowledge, and the translation of that knowledge into systems-based applications that can be used to diagnose and treat genetic diseases. Situated at the crossroads of engineering, biology, mathematics, statistics, and computer science, GSP requires the development of both nonlinear dynamical models that adequately represent genomic regulation, and diagnostic and therapeutic tools based on these models. This book facilitates these developments by providing rigorous mathematical definitions and propositions for the main elements of GSP and by paying attention to the validity of models relative to the data. Ilya Shmulevich and Edward Dougherty cover real-world situations and explain their mathematical modeling in relation to systems biology and systems medicine. Genomic Signal Processing makes a major contribution to computational biology, systems biology, and translational genomics by providing a self-contained explanation of the fundamental mathematical issues facing researchers in four areas: classification, clustering, network modeling, and network intervention.
| Author | : Edward R. Dougherty |
| Publisher | : Hindawi Publishing Corporation |
| Total Pages | : 456 |
| Release | : 2005 |
| Genre | : DNA microarrays |
| ISBN | : 9775945070 |
Recent advances in genomic studies have stimulated synergetic research and development in many cross-disciplinary areas. Processing the vast genomic data, especially the recent large-scale microarray gene expression data, to reveal the complex biological functionality, represents enormous challenges to signal processing and statistics. This perspective naturally leads to a new field, genomic signal processing (GSP), which studies the processing of genomic signals by integrating the theory of signal processing and statistics. Written by an international, interdisciplinary team of authors, this invaluable edited volume is accessible to students just entering this emergent field, and to researchers, both in academia and in industry, in the fields of molecular biology, engineering, statistics, and signal processing. The book provides tutorial-level overviews and addresses the specific needs of genomic signal processing students and researchers as a reference book. The book aims to address current genomic challenges by exploiting potential synergies between genomics, signal processing, and statistics, with special emphasis on signal processing and statistical tools for structural and functional understanding of genomic data. The first part of this book provides a brief history of genomic research and a background introduction from both biological and signal-processing/statistical perspectives, so that readers can easily follow the material presented in the rest of the book. In what follows, overviews of state-of-the-art techniques are provided. We start with a chapter on sequence analysis, and follow with chapters on feature selection, classification, and clustering of microarray data. We then discuss the modeling, analysis, and simulation of biological regulatory networks, especially gene regulatory networks based on Boolean and Bayesian approaches. Visualization and compression of gene data, and supercomputer implementation of genomic signal processing systems are also treated. Finally, we discuss systems biology and medical applications of genomic research as well as the future trends in genomic signal processing and statistics research.
| Author | : Aniruddha Datta |
| Publisher | : CRC Press |
| Total Pages | : 288 |
| Release | : 2018-10-08 |
| Genre | : Technology & Engineering |
| ISBN | : 1420006673 |
Studying large sets of genes and their collective function requires tools that can easily handle huge amounts of information. Recent research indicates that engineering approaches for prediction, signal processing, and control are well suited for studying multivariate interactions. A tutorial guide to the current engineering research in genomics, Introduction to Genomic Signal Processing with Control provides a state-of-the-art account of the use of control theory to obtain intervention strategies for gene regulatory networks. The book builds up the necessary molecular biology background with a basic review of organic chemistry and an introduction of DNA, RNA, and proteins, followed by a description of the processes of transcription and translation and the genetic code that is used to carry out the latter. It discusses control of gene expression, introduces genetic engineering tools such as microarrays and PCR, and covers cell cycle control and tissue renewal in multi-cellular organisms. The authors then delineate how the engineering approaches of classification and clustering are appropriate for carrying out gene-based disease classification. This leads naturally to expression prediction, which in turn leads to genetic regulatory networks. The book concludes with a discussion of control approaches that can be used to alter the behavior of such networks in the hope that this alteration will move the network from a diseased state to a disease-free state. Written by recognized leaders in this emerging field, the book provides the exact amount of molecular biology required to understand the engineering applications. It is a self-contained resource that spans the diverse disciplines of molecular biology and electrical engineering.
| Author | : Md. Zia Ur Rahman |
| Publisher | : CRC Press |
| Total Pages | : 202 |
| Release | : 2021-06-30 |
| Genre | : Science |
| ISBN | : 1000375153 |
This book addresses the issue of improving the accuracy in exon prediction in DNA sequences using various adaptive techniques based on different performance measures that are crucial in disease diagnosis and therapy. First, the authors present an overview of genomics engineering, structure of DNA sequence and its building blocks, genetic information flow in a cell, gene prediction along with its significance, and various types of gene prediction methods, followed by a review of literature starting with the biological background of genomic sequence analysis. Next, they cover various theoretical considerations of adaptive filtering techniques used for DNA analysis, with an introduction to adaptive filtering, properties of adaptive algorithms, and the need for development of adaptive exon predictors (AEPs) and structure of AEP used for DNA analysis. Then, they extend the approach of least mean squares (LMS) algorithm and its sign-based realizations with normalization factor for DNA analysis. They also present the normalized logarithmic-based realizations of least mean logarithmic squares (LMLS) and least logarithmic absolute difference (LLAD) adaptive algorithms that include normalized LMLS (NLMLS) algorithm, normalized LLAD (NLLAD) algorithm, and their signed variants. This book ends with an overview of the goals achieved and highlights the primary achievements using all proposed techniques. This book is intended to provide rigorous use of adaptive signal processing algorithms for genetic engineering, biomedical engineering, and bioinformatics and is useful for undergraduate and postgraduate students. This will also serve as a practical guide for Ph.D. students and researchers and will provide a number of research directions for further work. Features Presents an overview of genomics engineering, structure of DNA sequence and its building blocks, genetic information flow in a cell, gene prediction along with its significance, and various types of gene prediction methods Covers various theoretical considerations of adaptive filtering techniques used for DNA analysis, introduction to adaptive filtering, properties of adaptive algorithms, need for development of adaptive exon predictors (AEPs), and structure of AEP used for DNA analysis Extends the approach of LMS algorithm and its sign-based realizations with normalization factor for DNA analysis Presents the normalized logarithmic-based realizations of LMLS and LLAD adaptive algorithms that include normalized LMLS (NLMLS) algorithm, normalized LLAD (NLLAD) algorithm, and their signed variants Provides an overview of the goals achieved and highlights the primary achievements using all proposed techniques Dr. Md. Zia Ur Rahman is a professor in the Department of Electronics and Communication Engineering at Koneru Lakshmaiah Educational Foundation (K. L. University), Guntur, India. His current research interests include adaptive signal processing, biomedical signal processing, genetic engineering, medical imaging, array signal processing, medical telemetry, and nanophotonics. Dr. Srinivasareddy Putluri is currently a Software Engineer at Tata Consultancy Services Ltd., Hyderabad. He received his Ph.D. degree (Genomic Signal Processing using Adaptive Signal Processing algorithms) from the Department of Electronics and Communication Engineering at Koneru Lakshmaiah Educational Foundation (K. L. University), Guntur, India. His research interests include genomic signal processing and adaptive signal processing. He has published 15 research papers in various journals and proceedings. He is currently a reviewer of publishers like the IEEE Access and IGI.
| Author | : Rabinarayan Satpathy |
| Publisher | : John Wiley & Sons |
| Total Pages | : 433 |
| Release | : 2021-01-20 |
| Genre | : Computers |
| ISBN | : 111978560X |
Machine learning techniques are increasingly being used to address problems in computational biology and bioinformatics. Novel machine learning computational techniques to analyze high throughput data in the form of sequences, gene and protein expressions, pathways, and images are becoming vital for understanding diseases and future drug discovery. Machine learning techniques such as Markov models, support vector machines, neural networks, and graphical models have been successful in analyzing life science data because of their capabilities in handling randomness and uncertainty of data noise and in generalization. Machine Learning in Bioinformatics compiles recent approaches in machine learning methods and their applications in addressing contemporary problems in bioinformatics approximating classification and prediction of disease, feature selection, dimensionality reduction, gene selection and classification of microarray data and many more.
| Author | : Sudeep Tanwar |
| Publisher | : CRC Press |
| Total Pages | : 488 |
| Release | : 2021-12-10 |
| Genre | : Technology & Engineering |
| ISBN | : 1000487814 |
Machine Learning in Signal Processing: Applications, Challenges, and the Road Ahead offers a comprehensive approach toward research orientation for familiarizing signal processing (SP) concepts to machine learning (ML). ML, as the driving force of the wave of artificial intelligence (AI), provides powerful solutions to many real-world technical and scientific challenges. This book will present the most recent and exciting advances in signal processing for ML. The focus is on understanding the contributions of signal processing and ML, and its aim to solve some of the biggest challenges in AI and ML. FEATURES Focuses on addressing the missing connection between signal processing and ML Provides a one-stop guide reference for readers Oriented toward material and flow with regards to general introduction and technical aspects Comprehensively elaborates on the material with examples and diagrams This book is a complete resource designed exclusively for advanced undergraduate students, post-graduate students, research scholars, faculties, and academicians of computer science and engineering, computer science and applications, and electronics and telecommunication engineering.
| Author | : Hagit Messer |
| Publisher | : Frontiers Media SA |
| Total Pages | : 156 |
| Release | : 2022-12-12 |
| Genre | : Technology & Engineering |
| ISBN | : 2832500501 |
At present, less than 30% of researchers worldwide are women. As an estimate, this number is even lower in the field of Signal Processing, with some sources indicating it could be around 10%. Long-standing biases and gender stereotypes are discouraging girls and women away from science related fields, and STEM research in particular. Science and gender equality are, however, essential to ensure sustainable development as highlighted by UNESCO. In order to change traditional mindsets, gender equality must be promoted, stereotypes defeated, and girls and women should be encouraged to pursue STEM careers. Frontiers in Signal Processing is proud to offer this platform to promote the work of women researchers and engineers, across all areas of Signal Processing. The work presented here highlights the diversity of research performed across the entire breadth of the Signal Processing landscape, and presents advances in theory, experiment and methodology with applications to compelling problems. This article collection is open for submissions across all sections of the journal, and new articles will be added as they are published. Please note: to be considered for this collection, the corresponding author should be a female researcher.
| Author | : Abderrahim Elmoataz |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 639 |
| Release | : 2008-06-24 |
| Genre | : Computers |
| ISBN | : 354069904X |
This book constitutes the refereed proceedings of the Third International Conference on Image and Signal Processing, ICISP 2008, held in Cherbourg-Octeville, France, in July 2008. The 48 revised full papers and 22 revised poster papers presented were carefully reviewed and selected from 193 submissions. The papers are organized in topical sections on image filtering, image segmentation, computer vision, feature extraction, pattern recognition, graph-based representations, motion detection and estimation, new interfaces, document processing, and signal processing.
| Author | : Alamin Mansouri |
| Publisher | : Springer |
| Total Pages | : 410 |
| Release | : 2016-05-06 |
| Genre | : Computers |
| ISBN | : 3319336185 |
This book constitutes the refereed proceedings of the 7th International Conference, ICISP 2016, held in May/June 2016 in Trois-Rivières, QC, Canada. The 40 revised full papers were carefully reviewed and selected from 83 submissions. The contributions are organized in topical sections on features extraction, computer vision, and pattern recognition; multispectral and color imaging; image filtering, segmentation, and super-resolution; signal processing; biomedical imaging; geoscience and remote sensing; watermarking, authentication and coding; and 3d acquisition, processing, and applications.
| Author | : Winser Alexander |
| Publisher | : Academic Press |
| Total Pages | : 636 |
| Release | : 2016-11-14 |
| Genre | : Technology & Engineering |
| ISBN | : 0080885268 |
Digital signal processing (DSP) has been applied to a very wide range of applications. This includes voice processing, image processing, digital communications, the transfer of data over the internet, image and data compression, etc. Engineers who develop DSP applications today, and in the future, will need to address many implementation issues including mapping algorithms to computational structures, computational efficiency, power dissipation, the effects of finite precision arithmetic, throughput and hardware implementation. It is not practical to cover all of these in a single text. However, this text emphasizes the practical implementation of DSP algorithms as well as the fundamental theories and analytical procedures that form the basis for modern DSP applications. Digital Signal Processing: Principles, Algorithms and System Design provides an introduction to the principals of digital signal processing along with a balanced analytical and practical treatment of algorithms and applications for digital signal processing. It is intended to serve as a suitable text for a one semester junior or senior level undergraduate course. It is also intended for use in a following one semester first-year graduate level course in digital signal processing. It may also be used as a reference by professionals involved in the design of embedded computer systems, application specific integrated circuits or special purpose computer systems for digital signal processing, multimedia, communications, or image processing. - Covers fundamental theories and analytical procedures that form the basis of modern DSP - Shows practical implementation of DSP in software and hardware - Includes Matlab for design and implementation of signal processing algorithms and related discrete time systems - Bridges the gap between reference texts and the knowledge needed to implement DSP applications in software or hardware
