Genomic Diversity in People of India

Genomic Diversity in People of India
Author: Anthropological Survey Of India
Publisher: Springer Nature
Total Pages: 461
Release: 2021-07-02
Genre: Medical
ISBN: 9811601631

This book is the output of Anthropological Survey of India's National Project "DNA Polymorphism of Contemporary Indian Population" conducted during 2000 to 2018. The book compiles the independent and collaborative work of 49 scientific personnel. Genomics facilitate the study of genetic constitution and diversity at individual and population levels. Genomic diversity explains susceptibility, predisposition and prolongation of diseases; personalized medicine and longevity; prehistoric demographic events, such as population bottleneck, expansion, admixture and natural selection. This book highlights the heterogeneous, genetically diverse population of India. It shows how the central geographic location of India, played a crucial role in historic and pre-historic human migrations, and in peopling different continents of the world. The book describes the massive task undertaken by AnSI to unearth genomic diversity of India populations, with the use of Uni-parental DNA markers mtDNA (mitochondrial DNA) and Y –chromosome in 75 communities. The book talks about the 61 maternal and 35 paternal lineages identified through these studies. It brings forth interesting, hitherto unknown findings such as shared mutations between certain communities. This volume is a milestone in scientific research to understand biological diversity of Indian people at genomic level. It addresses the basic priority to identify different genes underlying various inborn genetic defects and diseases specific to Indian populations. This would be highly interesting to population geneticists, historians, as well as anthropologists.

Human Population Genetics

Human Population Genetics
Author: P.P. Majumder
Publisher: Springer Science & Business Media
Total Pages: 558
Release: 2012-12-06
Genre: Medical
ISBN: 1461529700

J. B. S. Haldane, R. A. Fisher and Sewall Wright simultaneously, and largely independently, laid the foundations of population genetics and the mathematical theory of evolution. Hal dane was born on November 5, 1892. Although he primarily worked at the University College London (UCL), in 1957 he resigned from the UCL and joined the Indian Statistical Institute, Calcutta (India) as a Research Professor. In celebration of his birth centenary, the Indian Statistical Institute organized an International Conference on Human Genetics from 15 to 19 December, 1992. The prime motive in holding this Conference was to bring together a group of scientists - geneticists, anthropologists, clinicians and statisticians - to evaluate the impact of Haldane's contributions to various areas of human genetics, and also to review recent developments in the subject. Session and lecture themes were so chosen that they covered areas theoretical and applied, classical and emerging. Speakers were then identified and invited to deliver lectures on these themes. Manuscripts of all invited presentations and a selected number of contributed presentations were considered for inclusion in this Proceed ings Volume. Each manuscript was reviewed by at least one Conference participant, which resulted in revision of several manuscripts and rejection of some. This volume is a collection of the manuscripts which have been 'accepted' after the review-process. The Conference began with the "J. B. S. Haldane Centenary Lecture" delivered by C. R. Rao.

Genomic Diversity

Genomic Diversity
Author: Surinder Singh Papiha
Publisher: Springer Science & Business Media
Total Pages: 268
Release: 2012-12-06
Genre: Social Science
ISBN: 1461542634

One of the major themes of human population genetics is assaying genetic variation in human populations. The ultimate goal of this objective is to understand the extent of genetic diversity and the use of this knowledge to reconstruct our evolutionary history. The discipline had undergone a revolutionary transition with the advent of molecular techniques in the 1980s. With this shift, statistical methods have also been developed to perceive the biological and molecular basis of human genetic variation. Using the new perspectives gained during the above transition, this volume describes the applications of molecular markers spanning the autosomal, Y-chromosomal and mitochondrial genome in the analysis of human diversity in contemporary populations. This is the first reference book of its kind to bring together data from these diverse sets of markers for understanding evolutionary histories and relationships of modern humans in a single volume.

Genetic Disorders of the Indian Subcontinent

Genetic Disorders of the Indian Subcontinent
Author: Dhavendra Kumar
Publisher: Springer Science & Business Media
Total Pages: 611
Release: 2012-09-15
Genre: Medical
ISBN: 140202231X

The Indian subcontinent is a vast land mass inhabited by over one billion people. Its rich and varied history is reflected by its numerous racial and ethnic groups and its distinct religious, cultural and social characteristics. Like many developing countries in Asia, it is passing through both demographic and epidemiological transitions whereby, at least in some parts, the diseases of severe poverty are being replaced by those of Westemisation; obesity, diabetes, and heart disease, for example. Indeed, as we move into the new millennium India has become a land of opposites; on the one hand there is still extensive poverty yet, on the other hand, some of the most remarkable developments in commerce and technology in Asia are taking place, notably in the fields of information technology and biotechnology. India has always fascinated human geneticists and a considerable amount of work has been done towards tracing the origins of its different ethnic groups. In the current excitement generated by the human genome project and the molecular and genetic approach to the study of human disease, there is little doubt that this field will develop and flourish in India in the future. Although so far there are limited data about genetic diseases in India, enough is known already to suggest that this will be an extremely fruitful area of research.

The Andaman Islanders

The Andaman Islanders
Author: Alfred Reginald Radcliffe-Brown
Publisher:
Total Pages: 558
Release: 1922
Genre: History
ISBN:

The Andaman Islanders: A Study in Social Anthropology by Alfred Reginald Radcliffe-Brown, first published in 1922, is a rare manuscript, the original residing in one of the great libraries of the world. This book is a reproduction of that original, which has been scanned and cleaned by state-of-the-art publishing tools for better readability and enhanced appreciation. Restoration Editors' mission is to bring long out of print manuscripts back to life. Some smudges, annotations or unclear text may still exist, due to permanent damage to the original work. We believe the literary significance of the text justifies offering this reproduction, allowing a new generation to appreciate it.

The Evolution and History of Human Populations in South Asia

The Evolution and History of Human Populations in South Asia
Author: Michael D. Petraglia
Publisher: Springer Science & Business Media
Total Pages: 463
Release: 2007-05-22
Genre: Social Science
ISBN: 1402055625

This is the first volume of its kind on prehistoric cultures of South Asia. The book brings together archaeologists, biological anthropologists, geneticists and linguists in order to provide a comprehensive account of the history and evolution of human populations residing in the subcontinent. New theories and methodologies presented provide new interpretations about the cultural history and evolution of populations in South Asia.

Ethics Dumping

Ethics Dumping
Author: Doris Schroeder
Publisher: Springer
Total Pages: 144
Release: 2017-12-04
Genre: Philosophy
ISBN: 3319647318

This open access book provides original, up-to-date case studies of “ethics dumping” that were largely facilitated by loopholes in the ethics governance of low and middle-income countries. It is instructive even to experienced researchers since it provides a voice to vulnerable populations from the fore mentioned countries. Ensuring the ethical conduct of North-South collaborations in research is a process fraught with difficulties. The background conditions under which such collaborations take place include extreme differentials in available income and power, as well as a past history of colonialism, while differences in culture can add a new layer of complications. In this context, up-to-date case studies of unethical conduct are essential for research ethics training.

Genetics of Castes and Tribes of India

Genetics of Castes and Tribes of India
Author: M. K. Bhasin
Publisher:
Total Pages: 534
Release: 2001
Genre: Human genetics
ISBN:

This Book Is Recommended To Geneticists, Demographers, Biomedical Scientists And Palaco-Anthropologists Whose Research In Directed To Increasing Ones Understanding Of The Biological Diversity And Evolution Of The Prehistoric And Modern Inhabitants Of The Indian Subcontinent.