Genomes And What To Make Of Them
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| Author | : Barry Barnes |
| Publisher | : ReadHowYouWant.com |
| Total Pages | : 506 |
| Release | : 2011-02 |
| Genre | : Science |
| ISBN | : 1459605934 |
The announcement in 2003 that the Human Genome Project had completed its map of the entire human genome was heralded as a stunning scientific breakthrough: our first full picture of the basic building blocks of human life. Since then, boasts about the benefits - and warnings of the dangers - of genomics have remained front-page news, with everyo...
| Author | : Barry Barnes |
| Publisher | : University of Chicago Press |
| Total Pages | : 281 |
| Release | : 2013-04-02 |
| Genre | : Science |
| ISBN | : 9780226054568 |
The announcement in 2003 that the Human Genome Project had completed its map of the entire human genome was heralded as a stunning scientific breakthrough: our first full picture of the basic building blocks of human life. Since then, boasts about the benefits—and warnings of the dangers—of genomics have remained front-page news, with everyone agreeing that genomics has the potential to radically alter life as we know it. For the nonscientist, the claims and counterclaims are dizzying—what does it really mean to understand the genome? Barry Barnes and John Dupré offer an answer to that question and much more in Genomes and What to Make of Them, a clear and lively account of the genomic revolution and its promise. The book opens with a brief history of the science of genetics and genomics, from Mendel to Watson and Crick and all the way up to Craig Venter; from there the authors delve into the use of genomics in determining evolutionary paths—and what it can tell us, for example, about how far we really have come from our ape ancestors. Barnes and Dupré then consider both the power and risks of genetics, from the economic potential of plant genomes to overblown claims that certain human genes can be directly tied to such traits as intelligence or homosexuality. Ultimately, the authors argue, we are now living with a new knowledge as powerful in its way as nuclear physics, and the stark choices that face us—between biological warfare and gene therapy, a new eugenics or a new agricultural revolution—will demand the full engagement of both scientists and citizens. Written in straightforward language but without denying the complexity of the issues, Genomes and What to Make of Them is both an up-to-date primer and a blueprint for the future.
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 128 |
| Release | : 1988-01-01 |
| Genre | : Science |
| ISBN | : 0309038405 |
There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
| Author | : John Quackenbush |
| Publisher | : Charlesbridge |
| Total Pages | : 189 |
| Release | : 2011-02-01 |
| Genre | : Science |
| ISBN | : 1607343568 |
The DNA sequence that comprises the human genome--the genetic blueprint found in each of our cells--is undoubtedly the greatest code ever to be broken. Completed at the dawn of a new millennium, the feat electrified both the scientific community and the general public with its tantalizing promise of new and better treatments for countless diseases, including Alzheimer's, cancer, diabetes, and Parkinson's. Yet what is arguably the most important discovery of our time has also opened a Pandora's box of questions about who we are as humans and how the unique information stored in our genomes can and might be used, making it all the more important for everyone to understand the new science of genomics. In the CURIOSITY GUIDE TO THE HUMAN GENOME, Dr. John Quackenbush, a renowned scientist and professor, conducts a fascinating tour of the history and science behind the Human Genome Project and the technologies that are revolutionizing the practice of medicine today. With a clear and engaging narrative style, he demystifies the fundamental principles of genetics and molecular biology, including the astounding ways in which genes function, alone or together with other genes and the environment, to either sustain life or trigger disease. In addition, Dr. Quackenbush goes beyond medicine to examine how DNA-sequencing technology is changing how we think of ourselves as a species by providing new insights about our earliest ancestors and reconfirming our inextricable link to all life on earth. Finally, he explores the legal and ethical questions surrounding such controversial topics as stem cell research, prenatal testing, forensics, and cloning, making this volume of the Curiosity Guides series an indispensable resource for navigating our brave new genomic world.
| Author | : Maxine F. Singer |
| Publisher | : Oxford University Press |
| Total Pages | : 179 |
| Release | : 2018-04-13 |
| Genre | : Science |
| ISBN | : 0192539175 |
How do plants, even if still buried underground, know that it's their time to bloom? What signals them to begin the challenging task of making flowers, and how do they make the variety of flower shapes, colours, and scents? What kind of instructions does the plant carry? Flowers enrich the beauty of meadows and gardens, but of course, they are not there simply to please us. Biologically, blossoms form a critical aspect of the reproductive cycle of many plants. In this book, the distinguished scientist Maxine Singer explains what we have pieced together about the genetics behind flowering. She describes in a clear and accessible account the key genes which, regulated by other genes, modulated by epigenetic effects, and responding to environmental cues, cause plants to flower at a particular time, and define the variety of flowers. The remarkably intricate processes involved in making flowers have evolved in nature alongside the pollinating birds and insects that the flowers must attract if there is to be another generation. The processes involved in flowering have only been unravelled in the past twenty years, and the implications for ensuring production of food, including fruits and seeds, are profound. This is cutting-edge science, and we have much still to learn, but the story being revealed that lies behind the flowers in our gardens, parks, and fields is proving astonishing.
| Author | : Scot McKnight |
| Publisher | : Brazos Press |
| Total Pages | : 343 |
| Release | : 2017-01-31 |
| Genre | : Religion |
| ISBN | : 1493406744 |
Genomic science indicates that humans descend not from an individual pair but from a large population. What does this mean for the basic claim of many Christians: that humans descend from Adam and Eve? Leading evangelical geneticist Dennis Venema and popular New Testament scholar Scot McKnight combine their expertise to offer informed guidance and answers to questions pertaining to evolution, genomic science, and the historical Adam. Some of the questions they explore include: - Is there credible evidence for evolution? - Do we descend from a population or are we the offspring of Adam and Eve? - Does taking the Bible seriously mean rejecting recent genomic science? - How do Genesis's creation stories reflect their ancient Near Eastern context, and how did Judaism understand the Adam and Eve of Genesis? - Doesn't Paul's use of Adam in the New Testament prove that Adam was a historical individual? The authors address up-to-date genomics data with expert commentary from both genetic and theological perspectives, showing that genome research and Scripture are not irreconcilable. Foreword by Tremper Longman III and afterword by Daniel Harrell.
| Author | : Kostas Kampourakis |
| Publisher | : Cambridge University Press |
| Total Pages | : 319 |
| Release | : 2017-03-30 |
| Genre | : Science |
| ISBN | : 1107567491 |
What are genes? What do genes do? These seemingly simple questions are in fact challenging to answer accurately. As a result, there are widespread misunderstandings and over-simplistic answers, which lead to common conceptions widely portrayed in the media, such as the existence of a gene 'for' a particular characteristic or disease. In reality, the DNA we inherit interacts continuously with the environment and functions differently as we age. What our parents hand down to us is just the beginning of our life story. This comprehensive book analyses and explains the gene concept, combining philosophical, historical, psychological and educational perspectives with current research in genetics and genomics. It summarises what we currently know and do not know about genes and the potential impact of genetics on all our lives. Making Sense of Genes is an accessible but rigorous introduction to contemporary genetics concepts for non-experts, undergraduate students, teachers and healthcare professionals.
| Author | : Dr. Euan Angus Ashley |
| Publisher | : Celadon Books |
| Total Pages | : 221 |
| Release | : 2021-02-23 |
| Genre | : Science |
| ISBN | : 1250234972 |
In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease. Since the Human Genome Project was completed in 2003, the price of genome sequencing has dropped at a staggering rate. It’s as if the price of a Ferrari went from $350,000 to a mere forty cents. Through breakthroughs made by Dr. Ashley’s team at Stanford and other dedicated groups around the world, analyzing the human genome has decreased from a heroic multibillion dollar effort to a single clinical test costing less than $1,000. For the first time we have within our grasp the ability to predict our genetic future, to diagnose and prevent disease before it begins, and to decode what it really means to be human. In The Genome Odyssey, Dr. Ashley details the medicine behind genome sequencing with clarity and accessibility. More than that, with passion for his subject and compassion for his patients, he introduces readers to the dynamic group of researchers and doctor detectives who hunt for answers, and to the pioneering patients who open up their lives to the medical community during their search for diagnoses and cures. He describes how he led the team that was the first to analyze and interpret a complete human genome, how they broke genome speed records to diagnose and treat a newborn baby girl whose heart stopped five times on the first day of her life, and how they found a boy with tumors growing inside his heart and traced the cause to a missing piece of his genome. These patients inspire Dr. Ashley and his team as they work to expand the boundaries of our medical capabilities and to envision a future where genome sequencing is available for all, where medicine can be tailored to treat specific diseases and to decode pathogens like viruses at the genomic level, and where our medical system as we know it has been completely revolutionized.
| Author | : Juan Enriquez |
| Publisher | : Penguin |
| Total Pages | : 386 |
| Release | : 2016-11-15 |
| Genre | : Science |
| ISBN | : 0143108344 |
An eye-opening, mind-bending exploration of how mankind is reshaping its genetic future, based on the viral TED Talk series “Will Our Kids Be a Different Species?” and “The Next Species of Human.” Are you willing to engineer the DNA of your unborn children and grand-children to be healthier? Better looking? More intelligent? Why are rates of autism, asthma, and allergies exploding at an unprecedented pace? Why are humans living longer and having far fewer kids? Futurist Juan Enriquez and scientist Steve Gullans conduct a sweeping tour of how humans are changing the course of evolution for all species—sometimes intentionally, sometimes not. For example: • What if life forms are limited only by the bounds of our imagination? Are designer babies and pets, de-extinction, even entirely newspecies fair game? • As humans, animals, and plants become ever more resistant to disease and aging, what will become the leading causes of death? • Man-machine interfaces may allow humans to live much longer. What will happen when we transfer parts of our “selves” into clones, into stored cells and machines? Though these harbingers of change are deeply unsettling, the authors argue we are also in an epoch of tremendous opportunity. Future humans, perhaps a more diverse, resilient, gentler, and intelligent species, may become better caretakers of the planet—but only if we make the right choices now. Intelligent, provocative, and optimistic, Evolving Ourselves is the ultimate guide to the next phase of life on Earth. Chosen by Nature magazine as a Fall 2016 season highlight.
| Author | : The Royal Society |
| Publisher | : National Academies Press |
| Total Pages | : 239 |
| Release | : 2021-01-16 |
| Genre | : Medical |
| ISBN | : 0309671132 |
Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.
