Genetics Of Pulmonary Disorders
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Author | : Takeshi Kaneko |
Publisher | : Springer |
Total Pages | : 340 |
Release | : 2018-07-12 |
Genre | : Medical |
ISBN | : 9811081441 |
This book describes the underlying genetic basis of common pulmonary diseases and discusses their pathogenesis and pathophysiology. These insights provide the basis for understanding different subtypes and phonotypes, and will promote better treatment strategies and individualized medicine. The book provides new and valuable information for the development of the areas of study, as well as practical guidelines for clinicians engaged in treating pulmonary diseases. This volume of the Respiratory Disease Series – Diagnostic Tools and Disease Managements will broaden the understanding of beginning and experienced researchers and clinicians who treat pulmonary diseases. Moreover, residents and clinicians engaged in medical oncology will find it a valuable guide to support them in their day-to-day work.
Author | : United States. Public Health Service. Office of the Surgeon General |
Publisher | : |
Total Pages | : 728 |
Release | : 2010 |
Genre | : Government publications |
ISBN | : |
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Author | : Jordan Prutkin |
Publisher | : Remedica |
Total Pages | : 207 |
Release | : 2002 |
Genre | : Lung Diseases |
ISBN | : 1901346455 |
Our understanding of the relationship between genetics and pulmonary disorders is still evolving. In 1989 cloning of the gene that, when mutated, causes cystic fibrosis marked a great advance in the study of genetic diseases. Yet, over a decade later, understanding of how this genetic defect leads to colonization by bacteria and inflammation in the lung remains elusive.
Author | : Stephen. D. Litwin |
Publisher | : CRC Press |
Total Pages | : 305 |
Release | : 2020-08-13 |
Genre | : Medical |
ISBN | : 1000110443 |
This book provides a current and integrated approach to the subject of genetic determinants of pulmonary disease with emphasis on physiologic derangements and genetic mechanisms. It describes the epidemiologic-genetic approach to chronic pulmonary disease.
Author | : Edwin Silverman |
Publisher | : CRC Press |
Total Pages | : 555 |
Release | : 2005-09-30 |
Genre | : Medical |
ISBN | : 0340814322 |
There has been a recent explosion of knowledge in the field of respiratory genetics. This authoritative text brings together current knowledge in respiratory genetics in a single volume. The book includes a comprehensive introductory section to provide guidance and aid understanding of key basic concepts in respiratory genetics, including statistical methods, sample collection, bioinformatics, and functional genomics. This is followed by a series of disease-specific chapters that review epidemiology, natural history, monogenic determinants, complex disease components, disease management, and likely future developments. Respiratory Genetics is an essential reference for pulmonologists, translational researchers, and clinical geneticists, and the text will also be a useful library reference.
Author | : Michael C. Iannuzzi |
Publisher | : |
Total Pages | : 2 |
Release | : 2003 |
Genre | : Lungs |
ISBN | : |
Author | : Summer Goodwin |
Publisher | : |
Total Pages | : 255 |
Release | : 2019-06-18 |
Genre | : |
ISBN | : 9781632416162 |
The pulmonary circulation is the part of the circulatory system, which transports deoxygenated blood away from the right ventricle of the heart to the lungs, and then returns the oxygenated blood to the left ventricle and atrium of the heart. The vessels involved in pulmonary circulation are pulmonary veins and pulmonary arteries. Pulmonary circulation can be affected by a number of conditions, chief among which are pulmonary hypertension, pulmonary embolus, vascular resistance, cardiac shunt and pulmonary shunt. Any disease that damages the lungs and affects their function may be called a chronic lung disease. It encompasses a number of clinical conditions which include idiopathic pulmonary fibrosis, chronic obstructive pulmonary disease, cystic fibrosis, emphysema, etc. Studies have shown a strong association of certain gene variants with impaired lung function. This book includes some of the vital pieces of work being conducted across the world, on various topics related to pulmonary diseases. It provides significant information of this discipline to help develop a good understanding of the role of genetics in the incidence of these disorders. Coherent flow of topics, student-friendly language and extensive use of examples make this book an invaluable source of knowledge.
Author | : Claude Gaultier |
Publisher | : Springer Science & Business Media |
Total Pages | : 338 |
Release | : 2007-10-18 |
Genre | : Medical |
ISBN | : 0387707646 |
"Provides an overview of the recent knowledge of the genetic factors underlying respiratory control disorders, an emerging field in respiratory biology. Identifying genes involved in respiratory control is crucial for understanding human diseases characterized by abnormal respiratory control." -- Back cover.
Author | : Joseph Loscalzo |
Publisher | : Harvard University Press |
Total Pages | : 449 |
Release | : 2017-02-01 |
Genre | : Medical |
ISBN | : 0674436539 |
Big data, genomics, and quantitative approaches to network-based analysis are combining to advance the frontiers of medicine as never before. With contributions from leading experts, Network Medicine introduces this rapidly evolving field of research, which promises to revolutionize the diagnosis and treatment of human diseases.
Author | : Dirkje S. Postma |
Publisher | : CRC Press |
Total Pages | : 456 |
Release | : 2007 |
Genre | : Medical |
ISBN | : |
Responding to the substantial growth that has taken place in the field over the past decade, this reference provides an in-depth overview of current thought on the genetics and genomics of asthma and COPD in relation to their pathogenesis and treatment. With contributions by an esteemed team of international authorities on the topic, this source spans the latest developments in the utilization of microarray techniques, linkage and association studies, mapping strategies, comparative genetics, microarray techniques, proteomics, and pharmacogenomics.