Genes Controlling Axonal Pathfinding In Drosophila
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The Embryonic Development of Drosophila melanogaster
Author | : Jose A. Campos-Ortega |
Publisher | : Springer Science & Business Media |
Total Pages | : 237 |
Release | : 2013-03-09 |
Genre | : Science |
ISBN | : 3662024543 |
" . . . but our knowledge is so weak that no philosoph er will ever be able to completely explore the nature of even a fly . . . " * Thornas Aquinas "In Syrnbolurn Apostolorum" 079 RSV p/96 This is a monograph on embryogenesis of the fruit fly Drosophi la melanogaster conceived as a reference book on morphology of embryonie development. A monograph of this extent and con tent is not yet available in the literature of Drosophila embryolo gy, and we believe that there is areal need for it. Thanks to the progress achieved during the last ten years in the fields of devel opmental and molecular genetics, work on Drosophila develop ment has considerably expanded creating an even greater need for the information that we present here. Our own interest for wildtype embryonie development arose several years ago, when we began to study the development of mutants. While those studies were going on we repeatedly had occasion to state in sufficiencies in the existing literature about the embryology of the wildtype, so that we undertook investigating many of these problems by ourselves. Convinced that several of our colleagues will have encountered similar difficulties we decided to publish the present monograph. Although not expressely recorded, Thomas Aquinas probably referred to the domestic fly and not to the fruit fly. Irrespective of which fly he meant, however, we know that Thomas was right in any case.
Brain Development in Drosophila melanogaster
Author | : Gerhard Martin Technau |
Publisher | : Springer Science & Business Media |
Total Pages | : 173 |
Release | : 2009-01-08 |
Genre | : Medical |
ISBN | : 0387782613 |
The fruitfly Drosophila melanogaster is an ideal model system to study processes of the central nervous system This book provides an overview of some major facets of recent research on Drosophila brain development.
Drosophila melanogaster: Practical Uses in Cell and Molecular Biology
Author | : |
Publisher | : Academic Press |
Total Pages | : 789 |
Release | : 1995-01-25 |
Genre | : Science |
ISBN | : 0080859429 |
Drosophila melanogaster: Practical Uses in Cell and Molecular Biology is a compendium of mostly short technical chapters designed to provide state-of-the art methods to the broad community of cell biologists, and to put molecular and cell biological studies of flies into perspective. The book makes the baroque aspects of genetic nomenclature and procedure accessible to cell biologists. It also contains a wealth of technical information for beginning or advanced Drosophila workers. Chapters, written within a year of publication, make this topical volume a valuable laboratory guide today and an excellent general reference for the future.Key Features* Collection of ready-to-use, state-of-the art methods for modern cell biological and related research using Drosophila melanogaster* Accessible to both experienced Drosophila researchers and to others who wish to join in at the cutting edge of this system * Drosophila offers an easily managed life cycle, inexpensive lifestyle, extraordinarily manipulable molecular and classical genetics, now combined with powerful new cell biology techniques * Introduction and overview sections orient the user to the Drosophila literature and lore * Six full-color plates and over 100 figures and tables enhance the understanding of these cell biology techniques
The Development of Drosophila Melanogaster
Author | : Michael Bate |
Publisher | : |
Total Pages | : 0 |
Release | : 2009 |
Genre | : Science |
ISBN | : 9780879698997 |
The fruit fly Drosophila melanogaster offers the most powerful means of studying embryonic development in eukaryotes. New information from many different organ systems has accumulated rapidly in the past decade. This monograph, written by the most distinguished workers in the field, is the most authoritative and comprehensive synthesis of Drosophila developmental biology available and emphasizes the insights gained by molecular and genetic analysis. In two volumes, it is a lavishly illustrated, elegantly designed reference work illustrating principles of genetic regulation of embryogenesis that may apply to other eukaryotes.
Neuronal Cytoskeleton
Author | : Hirokawa |
Publisher | : CRC Press |
Total Pages | : 360 |
Release | : 1994-01-12 |
Genre | : Science |
ISBN | : 9780849377419 |
This book discusses the primary functions of microtubule-associated proteins (MAPs) such as MAP2 and tau in neuronal morphogenesis, as well as relationships between neuronal differentiation and the expression of neuronal intermediate filaments (nestin, alpha internexin, and neurofilament triplet proteins). It emphasizes the importance of several cytoskeletal proteins for neuronal differentiation and morphogenesis, organelle transport, and synaptic functions. The book considers the involvement of tau MAPs in the formation of paired helical filaments in Alzheimer's disease, and it examines the mechanisms of organelle transports and molecular motors such as kinesin, braindynein, and kinesin superfamily proteins. Cytoskeletal proteins involved in synaptic formation and transmitter release and new synaptic junctional-associated proteins are explored as well.
Neuromuscular Junctions in Drosophila
Author | : |
Publisher | : Academic Press |
Total Pages | : 317 |
Release | : 1999-04-29 |
Genre | : Science |
ISBN | : 0080857779 |
Neuromuscular Junctions in Drosophila gathers the main contributions that research using the fruit fly Drosophila melanogaster has made in the area of synapse development, synapse physiology, and excitability of muscles and nerve cells. The chapters in this book represent a synthesis of major advances in our understanding of neuronal development and synaptic physiology, which have been obtained using the above approach.This book is directed to the general neuroscience audience: researchers, instructors, graduate students, and advanced undergraduates who are interested in the mechanisms of synapse development and physiology. However, the book will also be a valuable resource for those that use the fruit fly as a model system in their laboratories.Key Features* Synthesizes the genetic approaches used to study synaptic development and function at the neuromuscular junction, using flies as a model system* Covers major recent advances in muscle development, pathfinding, synapse maturation and plasticity, exo- and endocytosis, and ion channel function* Written in clear language that is easily understandable to readers not already familiar with fruit fly research* Includes numerous diagrams and extensive reference lists
A Comparative Methods Approach to the Study of Oocytes and Embryos
Author | : Joel D. Richter |
Publisher | : Oxford University Press, USA |
Total Pages | : 520 |
Release | : 1999-01 |
Genre | : Science |
ISBN | : 9780195115949 |
Over the past twenty years, biologists have made remarkable progress in understanding each step as a single fertilized egg develops into a mature organism, and the research draws on a tremendous array of experimental techniques. A Comparative Methods Approach to the Study of Oocytes and Embryos takes a unique approach to the field, providing a hands-on guide to three of the most important experimental subjects--frogs, fruitflies, and mice. By collecting reliable techniques in a single volume, the book is both an invaluable resource for new researchers and an ideal platform for comparing these seemingly disparate biological systems. The volume contains work from many leaders in the field and spans research in genetics, molecular and cellular biology, and morphology. It includes methods for oocyte and embryo culture, microinjection, in situ hybridization, immunohistochemistry, time-lapse microscopy, intracellular ion measurements, and embryonic dissections.
Drosophila: A laboratory manual
Author | : M. Ashburner |
Publisher | : Cold Spring Harbor Laboratory Press |
Total Pages | : 466 |
Release | : 1989 |
Genre | : Nature |
ISBN | : |
The Molecular Biology of Down Syndrome
Author | : G. Lubec |
Publisher | : Springer Science & Business Media |
Total Pages | : 380 |
Release | : 1999-12-02 |
Genre | : Medical |
ISBN | : 9783211833773 |
This book contains updated reviews and original research work on Down Syndrome focussing on brandnew results in neurobiology, in particular results on gene hunting (subtractive hybridization, differential display) and neurochemistry. The book provides new data such as a subtractive library of Down Syndrome brain showing cDNAs that are overexpressed or downregulated and can be regarded as a source for further research on the preliminary transcriptional data given. A 2D-electrophoretic map of human brain proteins including Down Syndrome brain protein expression established by in-gel-digestion of spots with subsequent MALDI-identification provides the scientific basis for protein work to the neuroscientist. Altogether, the book provides a series of new candidate genes possibly involved in Down Syndrome neurobiology, tools for neuroscience studies on Down Syndrome brain thus serving as a manual and updated views and aspects on Down Syndrome pathobiology.