Gene Probes
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| Author | : Marilena Aquino do Muro |
| Publisher | : Humana Press |
| Total Pages | : 272 |
| Release | : 2001-09-20 |
| Genre | : Science |
| ISBN | : 9780896038851 |
Senior scientists Marilena Aquino de Muro and Ralph Rapley have brought together an outstanding collection of time-tested protocols for designing and using genes probes in a wide variety of applications. The applications covered range from searching for specific genes in the human chromosome to the detection of microorganisms and their toxins in the environment and in food samples, as well as in the diagnosis of human disease. Helpful tutorials explain the principles of gene probe design, labeling, detection, target formation, and hybridization conditions.
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 199 |
| Release | : 1992-02-01 |
| Genre | : Science |
| ISBN | : 0309045878 |
Matching DNA samples from crime scenes and suspects is rapidly becoming a key source of evidence for use in our justice system. DNA Technology in Forensic Science offers recommendations for resolving crucial questions that are emerging as DNA typing becomes more widespread. The volume addresses key issues: Quality and reliability in DNA typing, including the introduction of new technologies, problems of standardization, and approaches to certification. DNA typing in the courtroom, including issues of population genetics, levels of understanding among judges and juries, and admissibility. Societal issues, such as privacy of DNA data, storage of samples and data, and the rights of defendants to quality testing technology. Combining this original volume with the new update-The Evaluation of Forensic DNA Evidence-provides the complete, up-to-date picture of this highly important and visible topic. This volume offers important guidance to anyone working with this emerging law enforcement tool: policymakers, specialists in criminal law, forensic scientists, geneticists, researchers, faculty, and students.
| Author | : |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2002 |
| Genre | : Cells |
| ISBN | : 9780815332183 |
| Author | : Iain Johnson |
| Publisher | : |
| Total Pages | : 1060 |
| Release | : 2010 |
| Genre | : Fluorescent probes |
| ISBN | : 9780982927915 |
The most complete fluorescent labeling and detection reference available, The Molecular Probes HandbookA Guide to Fluorescent Probes and Labeling Technologies contains over 3,000 technology solutions representing a wide range of biomolecular labeling and detection reagents. The significantly revised 11th Edition features extensive references, reorganized content, and new technical notes and product highlights.
| Author | : Alberto Macario |
| Publisher | : Elsevier |
| Total Pages | : 540 |
| Release | : 2012-12-02 |
| Genre | : Technology & Engineering |
| ISBN | : 0323146694 |
Gene Probes for Bacteria focuses on the preparation and use of nucleic acid probes for identifying bacteria in clinical specimens and in other samples of practical or scientific interest. Organized into 17 chapters, this book addresses which nucleic acid probes are available; how and when to utilize them; what to expect in terms of results obtained with their use; and how to prepare probes. Each chapter is composed of comprehensive manuscript covering different microorganisms. A few bacterial species are treated in more than one chapter to provide a multidimensional picture of important microbes, and to compile the knowledge gained from different laboratories using the same or different probes or methods. This reference material will be of great use to professionals, technicians, and R&D directors in universities, federal and state-dependent service and research institutes, and private and industrial laboratories.
| Author | : P. Michael Conn |
| Publisher | : Academic Press |
| Total Pages | : 483 |
| Release | : 2014-04-24 |
| Genre | : Science |
| ISBN | : 1483267857 |
Methods in Neurosciences, Volume 1: Gene Probes is a compendium of papers that deals with the developments in molecular biology, cell biology, and electrophysiology. Section I deals with gene expression using the Xenopus Oocyte system for expression and cloning of neuroreceptors and channels. One paper presents a method in studying the molecules in the brain related to neurotransmitter receptors and to the voltage channels in the brain by ""transplanting"" functional neurotransmitter receptors into the membrane of frog oocytes. Section II describes in situ and solution hybridization and the continuation of in situ hybridization with immunohistochemistry. One paper discusses the benefits of using alkaline phosphatase-Dig-dUTP-labeled oligonucleotide probes in high-resolution in situ in terms of ease of performance, safety, and fast detection rendering. Section III addresses the screening, sequencing, and cloning, the process of which includes the rapid identification of DNA clones. One paper outlines the methods and materials that are used in such identification. Section IV explains lineage analysis and Section V discusses molecular pathology, including the molecular pathology of Alzheimer's disease. This collection can prove useful for geneticists, molecular scientists, and academicians involved in neuroscience and pharmacological sciences, as well as researchers in geriatrics.
| Author | : United States. Food and Drug Administration. Division of Microbiology |
| Publisher | : |
| Total Pages | : 180 |
| Release | : 1969 |
| Genre | : Microbiology |
| ISBN | : |
| Author | : Fred C. Tenover |
| Publisher | : CRC Press |
| Total Pages | : 324 |
| Release | : 1988-11-30 |
| Genre | : Medical |
| ISBN | : 9780849361760 |
The process of developing nucleic acid probes for infectious agents and novel methods of detecting the binding of probes to the target DNA and RNA are reviewed in this thorough volume. Probes to a wide variety of bacterial, viral and protozoan pathogens are presented in detail by the leaders of this dynamic field. Also presented is the use of probes for antimicrobial susceptibility testing of bacteria and other infectious agents. The impact of the high cost of this technology on the clinical microbiology laboratory and on the food industry, versus the potential benefits of early diagnosis or recognition of contaminated foodstuffs, is considered. This volume is indispensable to those who work in the field of infectious diseases, including pathologists, microbiologists and infectious disease clinicians. In addition, food microbiologists will also find this volume to be a useful resource.
| Author | : K-H Liang |
| Publisher | : Woodhead Publishing |
| Total Pages | : 0 |
| Release | : 2013-07-31 |
| Genre | : Computers |
| ISBN | : 9781907568442 |
Contemporary biomedical and clinical research is undergoing constant development thanks to the rapid advancement of various high throughput technologies at the DNA, RNA and protein levels. These technologies can generate vast amounts of raw data, making bioinformatics methodologies essential in their use for basic biomedical and clinical applications. Bioinformatics for biomedical science and clinical applications demonstrates what these cutting-edge technologies can do and examines how to design an appropriate study, including how to deal with data and address specific clinical questions. The first two chapters consider Bioinformatics and analysis of the human genome. The subsequent three chapters cover the introduction of Transcriptomics, Proteomics and Systems biomedical science. The remaining chapters move on to critical developments, clinical information and conclude with domain knowledge and adaptivity.
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 128 |
| Release | : 1988-01-01 |
| Genre | : Science |
| ISBN | : 0309038405 |
There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
