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| Author | : Kay Elder |
| Publisher | : Cambridge University Press |
| Total Pages | : 229 |
| Release | : 2015-06-18 |
| Genre | : Business & Economics |
| ISBN | : 1107673178 |
Helping IVF laboratories and clinics to maintain the highest success rates possible, this is essential reading for every IVF laboratory.
| Author | : H.J.T Coelingh |
| Publisher | : CRC Press |
| Total Pages | : 260 |
| Release | : 1994-03-15 |
| Genre | : Science |
| ISBN | : 9781850705437 |
Designed as an aid for all clinicians and scientists who are currently engaged in the field of in vitro fertilization and other assisted conception techniques. The book provides a comprehensive account of gamete and embryo quality, and reflects up-to-date assessment of current knowledge.
| Author | : Kevin Coward |
| Publisher | : Cambridge University Press |
| Total Pages | : 408 |
| Release | : 2013-10-31 |
| Genre | : Medical |
| ISBN | : 110727625X |
The success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook – inspired by the postgraduate degree program at the University of Oxford – guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology.
| Author | : He-Feng Huang |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 229 |
| Release | : 2013-11-19 |
| Genre | : Health & Fitness |
| ISBN | : 9400777728 |
The book Gamete and Embryo-fetal Origins of Adult Diseases introduces various diseases resulting from the abnormal gametogenesis and embryo development, which manifests as growth retardation, birth defects, or increased susceptibility to chronic metabolic diseases such as diabetes, cardiovascular disease and cancer in childhood and adult life, even fertility disorders and the risk of transgenerational transmission. Six common kinds of these diseases are discussed in separate chapters. The authors explore the connections between these diseases and epigenetic reprogramming, rapid cell differentiation and organ formation and environmental influences, including assisted reproductive technology and adverse intrauterine environments. With a summary of findings on the causes and progression of adult diseases at the phase of gametogenesis and embryo development, this book provides insights into the pathogenesis of disease and aids in the treatment and prevention of disease, meeting the requirement for improving the quality of the newborn population, and effectively preventing and curing major diseases at an early stage. This book offers new perspectives and will be an enlightening resource for obstetricians, paediatricians, epidemiologists, endocrinologists and sanitarians. Editor He-Feng Huang, M.D., is Professor and President of Women’s Hospital, School of Medicine, Zhejiang University, China. Editor Jian-Zhong Sheng, Ph.D., is Professor at the Department of Pathology & Pathophysiology, School of Medicine, Zhejiang University, China.
| Author | : Markus Montag |
| Publisher | : CRC Press |
| Total Pages | : 328 |
| Release | : 2014-06-16 |
| Genre | : Medical |
| ISBN | : 1842145479 |
Among the many recent advances in assisted reproduction therapies (ART), improved technologies for identifying viable oocytes, sperm, and embryos are of primary importance. Paradoxically, the latest advances presented at conferences and symposia are often slow to become part of the daily routine in IVF laboratories. Detailing established and developing techniques, A Practical Guide to Selecting Gametes and Embryos provides a user-friendly text of ready-to-use ARTs that can be utilized effectively in the lab. In this volume, renowned embryologist and educator Markus Montag and his expert panel highlight sophisticated and proven selection strategies and emphasize the importance of proper lab practice in handling gametes and embryos. Topics include: Steps undertaken for the analysis of a semen sample Quality control and prevention of exposure to toxins in oocyte collection and embryo culture Morphological selection of gametes and embryos Both commonly used and innovative techniques for gamete and embryo selection, such as oxygen respiration and time-lapse imaging Invasive techniques, including polar body, embryo, and blastocyst biopsies as well as aneuploidy testing by FISH and array-CGH Accompanied by numerous figures and descriptions, this guide to selecting gametes and embryos brings the insight of international authors with knowledge and expertise, highlighting practical tips and key points. The book offers a starting point for applying successful selection strategies for reducing the rate of high-risk multiple gestations while maintaining or increasing viable pregnancy rates.
| Author | : Dmitry M. Kissin |
| Publisher | : Cambridge University Press |
| Total Pages | : 255 |
| Release | : 2019-07-04 |
| Genre | : Health & Fitness |
| ISBN | : 1108498582 |
Offers a comprehensive guide to assisted reproductive technology surveillance, describing its history, global variations, and best practices.
| Author | : Patrick Quinn |
| Publisher | : Cambridge University Press |
| Total Pages | : 307 |
| Release | : 2014-03-27 |
| Genre | : Medical |
| ISBN | : 1139917358 |
This volume describes culture media and solutions used in human ART; how they have been developed for in vitro human pre-implantation embryo development, the function and importance of the various components in media and solutions and how they interact, and how the systems in which these are used can influence outcomes. Chapters discuss inorganic solutes, energy substrates, amino acids, macromolecules, cytokines, growth factors, buffers, pH, osmolality, and the interaction of these parameters. The role of incubators and other physical factors are reviewed, along with the relevance and prospects of emerging technologies: morphokinetic analysis using time-lapse imaging and dynamic fluid incubation systems. Results of prospective randomized trials are emphasized to ascertain the added value of these techniques for selecting viable embryos. This comprehensive guide will be invaluable for embryologists, physicians and all personnel involved in the fluid products used in human ART seeking to optimize their successful use of these components.
| Author | : Kersti Lundin |
| Publisher | : Cambridge University Press |
| Total Pages | : 125 |
| Release | : 2021-05-06 |
| Genre | : Medical |
| ISBN | : 110887536X |
Whilst assisted reproduction techniques (ART) have become increasingly successful and largely standardized, there is still only a partial understanding of what constitutes a 'true' embryo environment. Replicating the varying physiological conditions of the in-vivo environment that the embryo travels through in the in-vitro culture is still a major challenge in ART. This practical volume details how to organize and operate an IVF laboratory in order to mimic these conditions for successful embryo culture. Environments and equipment that are essential for running safe and efficient facilities such as maintaining good air quality and hygiene protocols, and utilizing an effective layout are covered in detail. Other chapters discuss the different consumables needed, optimal handling techniques and parameter monitoring systems, as well as recent advances in the area including artificial intelligence and automation. This is an indispensable guide to understanding the background science of culturing embryos, crucial to successful outcomes in ART.
| Author | : Markus Montag |
| Publisher | : CRC Press |
| Total Pages | : 328 |
| Release | : 2014-06-16 |
| Genre | : Medical |
| ISBN | : 1040160794 |
Among the many recent advances in assisted reproduction therapies (ART), improved technologies for identifying viable oocytes, sperm, and embryos are of primary importance. Paradoxically, the latest advances presented at conferences and symposia are often slow to become part of the daily routine in IVF laboratories. Detailing established and develo
