GABAb Receptor Pharmacology: A Tribute to Norman Bowery

GABAb Receptor Pharmacology: A Tribute to Norman Bowery
Author:
Publisher: Academic Press
Total Pages: 521
Release: 2010-09-21
Genre: Medical
ISBN: 0123786487

This monograph was assembled to honor Professor Norman Bowery and his work on the 30th anniversary of his discovery of the GABAB receptor. In the present volume, leading neuroscientists from academia and industry provide a perspective of current research, both basic and translational, in the discovery of drugs acting at the GABAB receptor. The topics covered provide a comprehensive review of the field and the current state of research in this area. Included are chapters on the chemistry of GABAB agonists and antagonists, on the genetics and molecular composition of the site, its regulation and trafficking, and its role in controlling cellular, autonomic, and behavioral function. There are also chapters describing the potential clinical utility of drugs regulating GABAB activity receptor in the areas of hypertension, gastroesophageal reflux disease, Down syndrome, depression, and substance abuse. The information contained in this text will be of particular interest to neuroscientists in general and to neuropharmacologists in particular. - Articles written by leading investigators in the field - Informs and updates on all the latest developments

GABAb Receptor Pharmacology: A Tribute to Norman Bowery

GABAb Receptor Pharmacology: A Tribute to Norman Bowery
Author:
Publisher: Academic Press
Total Pages: 520
Release: 2010-08-18
Genre: Medical
ISBN: 9780123786470

This monograph was assembled to honor Professor Norman Bowery and his work on the 30th anniversary of his discovery of the GABAB receptor. In the present volume, leading neuroscientists from academia and industry provide a perspective of current research, both basic and translational, in the discovery of drugs acting at the GABAB receptor. The topics covered provide a comprehensive review of the field and the current state of research in this area. Included are chapters on the chemistry of GABAB agonists and antagonists, on the genetics and molecular composition of the site, its regulation and trafficking, and its role in controlling cellular, autonomic, and behavioral function. There are also chapters describing the potential clinical utility of drugs regulating GABAB activity receptor in the areas of hypertension, gastroesophageal reflux disease, Down syndrome, depression, and substance abuse. The information contained in this text will be of particular interest to neuroscientists in general and to neuropharmacologists in particular. Articles written by leading investigators in the field Informs and updates on all the latest developments

GABAB Receptor

GABAB Receptor
Author: Giancarlo Colombo
Publisher: Springer Nature
Total Pages: 349
Release:
Genre:
ISBN: 3031671481

Behavioral Neurobiology of GABAB Receptor Function

Behavioral Neurobiology of GABAB Receptor Function
Author: Styliani Vlachou
Publisher: Springer Nature
Total Pages: 331
Release: 2022-01-01
Genre: Medical
ISBN: 303091335X

It has been almost forty years since Norman G. Bowery discovered and named this “non-GABAA” receptor the GABAB receptor. It has been almost ten years since the last comprehensive book presentation focused on GABAB receptors. The main goal of this book is to provide the field with a contemporary and comprehensive perspective on the GABAB receptor, its physiological relevance, and its therapeutic potential. The volume is organized into introductory and special interest sections presented by experts who study the GABAB receptor from structural, signaling, pharmacologic, physiological, pathophysiological, and therapeutic perspectives. The book aims to appeal to a broad spectrum of biomedical and clinical scientists - any scholars with an interest in GABAB receptor. The editors hope readers find this work to be thought-provoking, instructive, and informative.

2011

2011
Author:
Publisher: Walter de Gruyter
Total Pages: 2983
Release: 2013-03-01
Genre: Reference
ISBN: 311031228X

Particularly in the humanities and social sciences, festschrifts are a popular forum for discussion. The IJBF provides quick and easy general access to these important resources for scholars and students. The festschrifts are located in state and regional libraries and their bibliographic details are recorded. Since 1983, more than 639,000 articles from more than 29,500 festschrifts, published between 1977 and 2010, have been catalogued.

Frontiers in Pharmacology of Neurotransmitters

Frontiers in Pharmacology of Neurotransmitters
Author: Puneet Kumar
Publisher: Springer Nature
Total Pages: 729
Release: 2020-10-29
Genre: Medical
ISBN: 9811535566

Numerous phenomenal advances have been made towards understanding the role of neurotransmitters in the pathophysiology of neurological disorders, and these have resulted in a large number of novel molecules with the potential to revolutionize the treatment and prevention of such disorders. This book provides a comprehensive and detailed explanation of brain neurotransmitters and their receptors and associated channels. It includes a basic introduction, and also discusses the functions and recent advances and their pharmacology, highlighting the role of various computer aided drug design (CADD) strategies for the development of therapeutic ligands to modulate these receptors/ion channels. Written in an easy-to-read style, it is intended for neuroscience and pharmaceutical students and researchers working in the area of brain neurotransmitters.

Current Concepts in Drug Metabolism and Toxicology

Current Concepts in Drug Metabolism and Toxicology
Author:
Publisher: Academic Press
Total Pages: 301
Release: 2012-11-27
Genre: Medical
ISBN: 0123983592

This new volume of Advances in Pharmacology explores the current concepts in drug metabolism and toxicology. Chapters cover the Keap1-Nrf2 cell defense pathway, animal models of drug-induced idiosyncratic toxicity and the use of human embryonic and induced pluripotent stem cells for modeling metabolism and toxicity. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike. - Explores the current concepts in drug metabolism and toxicology - Chapters cover such areas as the Keap1-Nrf2 cell defense pathway, animal models of drug-induced idiosyncratic toxicity and the use of human embryonic and induced pluripotent stem cells for modeling metabolism and toxicity - An essential resource for pharmacologists, immunologists and biochemists alike

Current State of Alzheimer's Disease Research and Therapeutics

Current State of Alzheimer's Disease Research and Therapeutics
Author: Elias K. Michaelis
Publisher: Academic Press
Total Pages: 400
Release: 2012-08-02
Genre: Medical
ISBN: 0123948169

"Providing a cross-section of current research, treatments and potential clinical developments, this volume of Advances in Pharmacology is an essential resource for biologists, pharmacologists and those engaged with Alzheimer's research."--P. [4] of cover.

Orthopedic Care of Patients with Cerebral Palsy

Orthopedic Care of Patients with Cerebral Palsy
Author: Philip D. Nowicki
Publisher: Springer Nature
Total Pages: 305
Release: 2020-06-22
Genre: Medical
ISBN: 3030465748

Many of the existing books focusing on the orthopedic management of patients with cerebral palsy encompass only care for the young patient, but this practical text reviews and delineates orthopedic care for patients with cerebral palsy throughout the lifespan. Readers will find a discussion of both non-operative and operative orthopedic management across all ages and functional levels. The text presents a general overview of cerebral palsy, evaluation of patients with cerebral palsy, and procedures commonly used to treat various orthopedic conditions in patients with cerebral palsy. Spasticity management and gait evaluation are likewise highlighted, and surgical chapters cover techniques for the hip, knee, foot and ankle, and spine. It also incorporates chapters focused on issues related to the rehabilitation of patients with cerebral palsy, including bracing, orthotics and other durable medical equipment, physical and occupational therapy, pain management, and adaptive activities and sports, which aim to improve the overall quality of life for patients through the lifespan. Finally, there is a chapter focused on the care transition from childhood to adulthood, an area of importance often neglected in current texts covering patients with cerebral palsy. Whether in the operating room, multi-specialty clinic or private office, Orthopedic Care of Patients with Cerebral Palsy will be a go-to resource for orthopedists, pediatricians and all medical professionals caring for this population.

Diversity and Functions of GABA Receptors: A Tribute to Hanns Möhler, Part B

Diversity and Functions of GABA Receptors: A Tribute to Hanns Möhler, Part B
Author:
Publisher: Academic Press
Total Pages: 285
Release: 2015-01-27
Genre: Science
ISBN: 012802691X

Diversity and Functions of GABA Receptors: A Tribute to Hanns Möhler, Part B, a new volume of Advances in Pharmacology, presents the diversity and functions of GABA Receptors. The volume looks at research performed in the past 20 years, which has revealed specific physiological and pharmacological functions of individual GABAA receptor subtypes, providing novel opportunities for drug development. - Contributions from the best authors in the field - An essential resource for pharmacologists, immunologists, and biochemists