Fungal Metabolites

Fungal Metabolites
Author: Jean-Michel Mérillon
Publisher: Springer
Total Pages: 0
Release: 2017-02-20
Genre: Science
ISBN: 9783319250007

This handbook compiles authoritative information about fungal metabolites and their chemistry and biotechnology. The first in the reference work series “Phytochemicals”, and written by a team of international expert authors, this book provides reference information ranging from the description of fungal natural products, over their use e.g. as anticancer agents, to microbial synthesis, even spanning to the production of secondary metabolites on industrial scale. On the other hand it also describes global health issues related to aflatoxin production in foods and agriculture, including perspectives for detoxification. The handbook characterizes different compound classes derived from fungal secondary metabolites, like ergot alkaloids and aflatoxins. The discussion puts a special emphasis on how potentially useful compounds can be obtained and what applications they can find, on the one hand, and how potential dangers can be encountered on the other hand. The comprehensive chapters in this handbook will thus appeal to readers from diverse backgrounds in chemistry, biology, life sciences, and even medicine, who are working or planning to work with fungal (secondary) metabolites and their application. They provide the readers with rich sources of reference information on important topics in this field.

Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites, Volume 2

Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites, Volume 2
Author: Susanne Zeilinger
Publisher: Springer
Total Pages: 263
Release: 2015-06-15
Genre: Science
ISBN: 1493925318

​Fungi produce many chemically diverse secondary metabolites whose biological roles largely remain elusive. Within the increasing number of sequenced fungal genomes several important genes involved in secondary metabolite formation have been identified. Most of these genes are clustered and their coordinated transcription is controlled in a complex way by both narrow pathway-specific regulators as well as broad global transcription factors responsive to environmental cues. In recent years it was discovered many of the newly identified gene clusters are silent under laboratory conditions suggesting that the biosynthetic potential of fungi is far from being exploited. Besides identifying novel bioactive metabolites from still unexplored sources, the activation of these gene clusters by several approaches may result in the discovery of new substances with antibiotic and pharmaceutical benefits. This book covers recent advances in the field of fungal secondary metabolisms ranging from methodologies to biological aspects and will include the latest knowledge on fungal molecular biology, genomics, and metabolomics. With the related volume by Professor Juan-Francisco Martin, where the most relevant and well-studied fungal secondary metabolites are compiled, this book provides a comprehensive overview of the state-of-the-art of research on fungal secondary metabolites.

Modern Concepts in Penicillium and Aspergillus Classification

Modern Concepts in Penicillium and Aspergillus Classification
Author: Robert A. Samson
Publisher: Springer Science & Business
Total Pages: 502
Release: 1990-07-31
Genre: Science
ISBN: 9780306435164

In our view, the First International Penicillium and Aspergillus Workshop held in Baarn and Amsterdam in May, 1985, was a great success. The assembly in one place of so many specialists in these two genera produced both interesting viewpoints and lively discussions. But more particularly, a remarkable cohesion of ideas emerged, borne primarily of the realisation that taxonomy has passed from the hands of the solitary morphologist. The future of taxonomy lay in collaborative and multidisciplinary studies embracing morphology, physiology and newer methodologies. Penicillium and Aspergillus Workshop was borne logically The Second International from the first, and was held in Baarn on May 8-12, 1989. It was attended by 38 scientists from 16 countries. At this Workshop we have attempted to move further into new methods, especially by bringing together molecular biologists, medical and food mycologists and biochemists as well as more traditional taxonomists. We feel that the meeting contributed greatly to dialogue between taxonomists, and also fundamental and applied mycologists. At the meeting, we became aware that the approach to taxonomy of these genera is now becoming more pragmatic, with an increasing emphasis on consensus, and on stability of names. This is a noteworthy development, which we, as editors, welcome. So many species in Penicillium and Aspergillus are economically important in biotechnology, foods and medicine, and practical, stable taxonomy is of vital importance. These Proceedings comprise 40 papers divided into 9 chapters.

Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites

Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites
Author: Juan-Francisco Martín
Publisher: Springer
Total Pages: 357
Release: 2014-09-09
Genre: Science
ISBN: 1493911910

This volume describes the more relevant secondary metabolites of different fungi with current information on their biosynthesis and molecular genetics. Bolstered with color illustrations and photographs, the book describes the possible application of molecular genetics to directed strain improvement in great detail. The needs for future developments in this field are also discussed at length Written by authorities in the field, Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites provides a cutting-edge perspective on fungal secondary metabolism and underlying genetics and is a valuable resource for scientists, researchers, and educators in the field of fungal biology.

Bioactive Metabolites of Endophytic Fungi from Medicinal Plant

Bioactive Metabolites of Endophytic Fungi from Medicinal Plant
Author: Rezwana Khan
Publisher: LAP Lambert Academic Publishing
Total Pages: 228
Release: 2010-12
Genre:
ISBN: 9783843375443

It is a big challenge towards the scientists to meet the demand of ever increasing population in the world. Development of drug resistant pathogenic microorganisms, emergence of new diseases, appearance of life threatening viruses, management of post operative complication in patient with organ transplantation are some of the problems of twenty first century. It is necessary to identify safe and bioactive molecules to solve these problems. Different natural sources should be explored for this purpose. Endophytic fungus is one of the unexplored groups of organism. They are highly potent to produce bioactive compounds and can be considered as a source of novel secondary metabolites for medical, agricultural or industrial exploitation. This book comprises the research work on endophytic fungi. It provides the information about the endophytic fungi, procedure of isolation, identification and characterization of metabolites. This book will be useful to the young scientists especially those are working on drug development and drug discovery from natural product.

Endophytic Fungi

Endophytic Fungi
Author: Evelyn Hughes
Publisher: Nova Science Publishers
Total Pages: 0
Release: 2016-12-31
Genre: Medical
ISBN: 9781536103410

Endophytic fungi are important biotechnological tools because they produce many secondary metabolites. However, to access this important source of bioactive molecules, it is essential to explore the diversity of endophytic fungi and catalog their species richness in different ecosystems. This book reviews the diversity, characterisation and biocontrol of endophytic fungi.

Fungi and Fungal Metabolites for the Improvement of Human and Animal Nutrition and Health

Fungi and Fungal Metabolites for the Improvement of Human and Animal Nutrition and Health
Author: Laurent Dufoss ́e
Publisher: Mdpi AG
Total Pages: 460
Release: 2021-09-30
Genre: Science
ISBN: 9783036514666

The purpose of this book was not to provide a comprehensive overview of the vast arena of how fungi and fungal metabolites are able to improve human and animal nutrition and health; rather, we, as Guest Editors, wished to encourage authors working in this field to publish their most recent work in this rapidly growing journal in order for the large readership to appreciate the full potential of wonderful and beneficial fungi. Thus, this Special Issue welcomed scientific contributions on applications of fungi and fungal metabolites, such as bioactive fatty acids, pigments, polysaccharides, alkaloids, terpenoids, etc., with great potential in human and animal nutrition and health.