If nothing else, 2020 reminded us that, whether we like it or not, human society forms part of a broader ecological community that includes species with management challenges. My experience in Melbourne highlighted how environmental threats to humanity are best managed when governments adopt evidence-based strategies (that might also require incentives for human cooperation). Fundamental research, ranging from quantitative natural history to broader insights about ecological and evolutionary processes, invariably forms the backbone of such evidence. The collection of papers in this 2020 Highlights eBook represents a sample of articles in Frontiers in Ecology and Evolution that contribute to our collective wisdom in the discipline and generated sizeable interest among our readers. We hope you also find them interesting.