Of Molecules and Men

Of Molecules and Men
Author: Francis Crick
Publisher:
Total Pages: 0
Release: 2004
Genre: Biology
ISBN: 9781591021858

"In his third lecture Crick anticipates events and trends that have in fact come to pass in the past four decades, including the increasing use of computer technology and robotics in mind-brain research, explorations into right-side versus left-side uses of the brain, and controversies surrounding the existence of the soul."--BOOK JACKET.

Bacterial Resistance to Antibiotics

Bacterial Resistance to Antibiotics
Author: Boyan B. Bonev
Publisher: John Wiley & Sons
Total Pages: 288
Release: 2019-06-10
Genre: Science
ISBN: 111994077X

AN AUTHORITATIVE SURVEY OF CURRENT RESEARCH INTO CLINICALLY USEFUL CONVENTIONAL AND NONCONVENTIONAL ANTIBIOTIC THERAPEUTICS Pharmaceutically-active antibiotics revolutionized the treatment of infectious diseases, leading to decreased mortality and increased life expectancy. However, recent years have seen an alarming rise in the number and frequency of antibiotic-resistant "Superbugs." The Centers for Disease Control and Prevention (CDC) estimates that over two million antibiotic-resistant infections occur in the United States annually, resulting in approximately 23,000 deaths. Despite the danger to public health, a minimal number of new antibiotic drugs are currently in development or in clinical trials by major pharmaceutical companies. To prevent reverting back to the pre-antibiotic era—when diseases caused by parasites or infections were virtually untreatable and frequently resulted in death—new and innovative approaches are needed to combat the increasing resistance of pathogenic bacteria to antibiotics. Bacterial Resistance to Antibiotics – From Molecules to Man examines the current state and future direction of research into developing clinically-useful next-generation novel antibiotics. An internationally-recognized team of experts cover topics including glycopeptide antibiotic resistance, anti-tuberculosis agents, anti-virulence therapies, tetracyclines, the molecular and structural determinants of resistance, and more. Presents a multidisciplinary approach for the optimization of novel antibiotics for maximum potency, minimal toxicity, and appropriated degradability Highlights critical aspects that may relieve the problematic medical situation of antibiotic resistance Includes an overview of the genetic and molecular mechanisms of antibiotic resistance Addresses contemporary issues of global public health and longevity Includes full references, author remarks, and color illustrations, graphs, and charts Bacterial Resistance to Antibiotics – From Molecules to Man is a valuable source of up-to-date information for medical practitioners, researchers, academics, and professionals in public health, pharmaceuticals, microbiology, and related fields.

The Ables

The Ables
Author: Jeremy Scott
Publisher: Turner Publishing Company
Total Pages: 356
Release: 2019-06-11
Genre: Young Adult Fiction
ISBN: 1684423384

I did have fantastic hearing, mostly by virtue of being blind. But that couldn't actually mean that he's trying to tell me I have super powers, right? Because that would be ridiculous. It wasn't the "sex talk" he expected. Phillip Sallinger's dad has told him he's a custodian--a guardian--and his genetically inherited power is telekinesis. He'll learn to move objects with his mind. Excited to begin superhero high school until he discovers he's assigned to a "special ed" class for disabled empowered kids, he suddenly feels like an outsider. Bullied, threatened, and betrayed, Phillip struggles, even as he and his friends--calling themselves the Ables--find ways to maximize their powers to overcome their disabilities, and are the first to identify the growing evil threatening humanity. As vital custodians disappear and the custodian leadership is mired in indecision, a mysterious and powerful figure taunts Phillip, and the enemy is poised to strike. But what if the next "one who does all," the multi-gifted custodian predicted to come, is one of the Ables?

Marvels

Marvels
Author: Kurt Busiek
Publisher: Marvel Entertainment
Total Pages: 163
Release: 2010-07-07
Genre: Comics & Graphic Novels
ISBN: 0785179569

Collects Marvels: Eye of the Camera #1-6. News photographer Phil Sheldon's back, with the man-on-the-street's perspective on the big events of the Marvel Universe, from the Avengers, the all-new X-Men and the Secret Wars to Dracula and the Werewolf By Night. But this time, Phil's world is going to be rocked not just by superheroes and super-villains -- but by something far more personal, as well.

Creating a Physical Biology

Creating a Physical Biology
Author: Phillip R. Sloan
Publisher: University of Chicago Press
Total Pages: 331
Release: 2011-12-15
Genre: Science
ISBN: 0226767825

Despite its historical impact on the biological sciences, the paper entitled 'On the Nature of Gene Mutation and Gene Structure' has remained largely inaccessible because it was only published in a short-lived German periodical. This book makes the 'Three Man' Paper available in English for the first time.

An Introduction to Interdisciplinary Toxicology

An Introduction to Interdisciplinary Toxicology
Author: Carey N. Pope
Publisher: Academic Press
Total Pages: 644
Release: 2020-03-06
Genre: Medical
ISBN: 0128136022

An Introduction to Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology, from "simple” molecular systems, to complex human communities, with expertise from a spectrum of interacting disciplines. Chapters are written by specialists within a given subject, such as a chemical engineer, nutritional scientist, or a microbiologist, so subjects are clearly explained and discussed within the toxicology context. Many chapters are comparative across species so that students in ecotoxicology learn mammalian toxicology and vice versa. Specific citations, further reading, study questions, and other learning features are also included. The book allows students to concurrently learn concepts in both biomedical and environmental toxicology fields, thus better equipping them for the many career opportunities toxicology provides. This book will also be useful to those wishing to reference how disciplines interact within the broad field of toxicology. Covers major topics and newer areas in toxicology, including nanotoxicology, Tox21, epigenetic toxicology, and organ-specific toxicity Includes a variety of perspectives to give a complete understanding of toxicology Written by specialists within each subject area, e.g., a chemical engineer, to ensure concepts are clearly explained

Molecular Biology of the Male Reproductive System

Molecular Biology of the Male Reproductive System
Author: David de Kretser
Publisher: Elsevier
Total Pages: 502
Release: 2012-12-02
Genre: Science
ISBN: 008091764X

Written by experts in their respective fields, this book reviews the expanding knowledge concerning the mechanisms regulating male reproduction at the molecular and cellular levels. It covers the development of the testes and regulatory controls for spermatogenesis and steroidogenesis, and it considers aspects of Sertoli cell function. Areas of emphasis include communication between the various cell types involved in reproduction by hormone and growth factors and the mechanisms by which these factors regulate gene expression. A number of mammalian systems, including humans, are covered. The carefully selected authors provide a clear synopsis of the concepts in each area as well as the latest references, enabling the reader to investigate the topic further. This book is of interest to those seeking an understanding of the regulatory mechanisms in male reproduction and is written for the graduate and postgraduate levels. - Provides up-to-date reviews of the molecular and cellular biology of male reproduction - Includes chapters on the developmental biology of the testes - Links conventional hormonal control of testicular function with the evolving role of growth factors and proto-oncogenes

Pathophysiology of Headaches

Pathophysiology of Headaches
Author: Messoud Ashina
Publisher: Springer
Total Pages: 277
Release: 2015-04-14
Genre: Medical
ISBN: 3319156217

This book provides a detailed overview of the current state of knowledge regarding the pathophysiology of both primary headaches – migraine, tension-type headache (TTH), and cluster headache – and the very important and frequent type of secondary headache, medication overuse headache (MOH). After an introductory chapter describing relevant neuroanatomy and vascular anatomy, the evidence gained from animal models regarding the pathophysiology of migraine and the other primary headaches is reviewed. Knowledge of the genetic component in the different types of headache is then examined with reference to recent evidence, for example regarding the implication of the trigeminovascular system and cortical spreading depression in migraine. Detailed information is provided on insights into primary headaches from imaging studies, including functional magnetic resonance imaging and positron emission tomography and on their neurophysiology and biochemistry. A further series of important chapters describe present knowledge of the pathophysiology of each specific type of headache and consider future directions. Written by acknowledged experts in their fields from Europe and the United States, clinicians and students will find Pathophysiology of Headaches to be an excellent source of up-to-date information on why patients experience headaches. In addition, it will be of value for pain researchers investigating the underlying mechanisms of headache.

Exploring the Biological Contributions to Human Health

Exploring the Biological Contributions to Human Health
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 287
Release: 2001-07-02
Genre: Medical
ISBN: 0309132975

It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.