Fractionated Hyperthermia and Thermotolerance
Author | : Ole Steen Nielson |
Publisher | : |
Total Pages | : 53 |
Release | : 1984 |
Genre | : Experimental immunology |
ISBN | : |
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Author | : Ole Steen Nielson |
Publisher | : |
Total Pages | : 53 |
Release | : 1984 |
Genre | : Experimental immunology |
ISBN | : |
Author | : M. Urano |
Publisher | : VSP |
Total Pages | : 368 |
Release | : 1994-04 |
Genre | : Science |
ISBN | : 9789067641661 |
The number of studies on the use of hyperthermia in combination with chemotherapeutic agents is steadily increasing. However, thermochemotherapy has not yet captured significant clinical interest. Therefore, this fourth volume in the book series Hyperthermia and Oncology deals with this topic, as the editors feel there is a significant potential for this combined modality as an adjuvant to palliative or definitive radiotherapy, or the use of chemotherapy alone to treat localized or advanced diseases. The articles in this volume deal with various aspects of chemotherapy combined with hyperthermia and will be of value and interest to researchers in this field.
Author | : M.Heinrich Seegenschmiedt |
Publisher | : Springer Science & Business Media |
Total Pages | : 479 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 3642578586 |
Hyperthermia has been found to be of great benefit in combination with radiation therapy or chemotherapy in the management of patients with difficult and com plicated tumor problems. It has been demonstrated to increase the efficacy, of ionising radiation when used locally but also has been of help in combination with systemic chemotherapy where hyperthermia is carried out to the total body. Problems remain with regard to maximizing the effects of hyperthermia as in fluenced by blood flow, heat loss, etc. The present volume defines the current knowledge relative to hyperthermia with radiation therapy and/or chemotherapy, giving a comprehensive overview of its use in cancer management. Philadelphia/Hamburg, June 1995 L.W. BRADY H.-P. HEILMANN Preface In an attempt to overcome tumor resistance, hypoxia, or unfavorable tumor condi tions, oncological research has come to focus on gene therapy, immunotherapy, new cytotoxic agents, and increasingly sophisticated radiotherapy. Radiation research has been directed towards heavy particle therapy and modification of the radiation response by either protecting or sensitizing agents. Improved dose localization using rotational or conformal strategies has also been implemented. Recently, changes in radiation fractionation schedules have shown promise of better results. Hyperthermia in cancer therapy can be viewed similarly as another means to increase the sensitivity of tumors to radio- and chemotherapy.
Author | : Andras Szasz |
Publisher | : Springer Science & Business Media |
Total Pages | : 575 |
Release | : 2010-11-23 |
Genre | : Medical |
ISBN | : 9048194989 |
Oncothermia is the next generation medical innovation that delivers selective, controlled and deep energy for cancer treatment. The basic principles for oncothermia stem from oncological hyperthermia, the oldest approach to treating cancer. Nevertheless, hyperthermia has been wrought with significant controversy, mostly stemming from shortcomings of controlled energy delivery. Oncothermia has been able to overcome these insufficiencies and prove to be a controlled, safe and efficacious treatment option. This book is the first attempt to elucidate the theory and practice of oncothermia, based on rigorous mathematical and biophysical analysis, not centered on the temperature increase. It is supported by numerous in-vitro and in-vivo findings and twenty years of clinical experience. This book will help scientists, researchers and medical practitioners in understanding the scientific and conceptual underpinnings of oncothermia and will add another valuable tool in the fight against cancer. Professor Andras Szasz is the inventor of oncothermia and the Head of St Istvan University's Biotechnics Department in Hungary. He has published over 300 papers and lectured at various universities around the world. Dr. Oliver Szasz is the managing director of Oncotherm, the global manufacturer and distributor of medical devices for cancer treatment used in Europe & Asia since the late 1980s. Dr. Nora Szasz is currently a management consultant in healthcare for McKinsey & Co.
Author | : S.B. Field |
Publisher | : Springer Science & Business Media |
Total Pages | : 672 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 9400935978 |
In the 1960s a firm rationale was developed for using raised temperatures to treat malignant disease and there has been a continuous expansion of the field ever since. However, a major limitation exists in our ability to heat human tumours, especially those sited deep in the body, with a reasonable degree of temperature uniformity. This problem has resulted in engineers and physicists collaborating closely with biologists and clinicians towards the common goal of developing and testing the clinical potential of this exciting treatment modality. The aim of the physicist and engineer is to develop acceptible methods of heating tumQur masses in as many sites as possible to therapeutic temperatures avoiding excessive heating of normal structures and, at the same time, obtaining the temperature distribution throughout the heated volume. The problem is magnified by both the theoretical and technical limitations of heating methods and devices. Moreover, the modelling of external deposition of energy in tissue and knowledge of tissue perfusion are ill-defined. To this must be added the conceptual difficulty of defining a thermal dose. The NATO course was designed to provide a basis for the integration of physics and technology relevant to the development of hyperthermia. There were 48 lectures covering the theoretical and practical aspects of system design and assessment, including, as far as possible, all the techniques of current interest and importance in the field.
Author | : National Cancer Institute (U.S.) |
Publisher | : |
Total Pages | : 584 |
Release | : 1982 |
Genre | : Cancer |
ISBN | : |
Author | : Wolfgang Hinkelbein |
Publisher | : Springer Science & Business Media |
Total Pages | : 429 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 3642832636 |
Physicians and biologists here present their experimental work in the field of hyperthermia, paying particular regard to its relevance in clinical situations. Principles of heat action and combined treatment modalities are explicated. The main topics discussed are the effects of such treatment on normal tissues, animal tumors, malignant cell lines and human tumors.
Author | : Haim I. Bicher |
Publisher | : Springer Science & Business Media |
Total Pages | : 545 |
Release | : 2013-03-08 |
Genre | : Medical |
ISBN | : 1468457667 |
Hyperthermia as a safe and effective cancer treatment modality is rapidly evolving propelled by widespread research and clinical efforts worldwide. Presentations on Hyperthermia experience are now commonplace at Oncology meetings, as are congresses dedicated entirely to the intertwined interactions between basic sciences and patient treatment that together are forming the structure of a new medical specialty. Such was the XII International Symposium on Clinical Hyperthermia held in Rome, Italy, April 27 - 29, 1989. Papers presented therein constitute the backbone of this book. Biology research has provided data describing mechanisms of action for the cancer cell killing and physiological effects of Hyperthermia. Physics research has led to the development of equipment enabling treatment of many areas of the human body, as well as explained the limitations that still constrain our ability to treat, especially in the areas of deep seated tumor heating and non-invasive thermometry. The main question that will decide the future of this modality is that of its clinical use. To put it succinctly, what do we do with this potentially useful tool in an everyday clinical oncological practice . •• ? This is the main question addressed in this book as "Consensus on Hyperthermia for the 1990s. " The book in cludes 28 presented papers and 25 invited chapters from some of the leading experts in the field. Their basic mechanisms of action were physics principles, treatment quality assurance and especially, clinical indications.
Author | : Leopold J. Anghileri |
Publisher | : CRC Press |
Total Pages | : 345 |
Release | : 2019-06-04 |
Genre | : Medical |
ISBN | : 1000012670 |
First published in 1986, Hyperthermia in Cancer Treatment is a most useful guide to the relationship between Hyperthermia, and the ways in which it is used for the control and treatment of cancer cells. Well-structured and comprehensive, this book is a must-read for any students of Oncology or professionals in their respective fields.