“Fortification of Topical Minoxidil with Finasteride”: An account of upkeep of hair density after replacing oral Finasteride.

“Fortification of Topical Minoxidil with Finasteride”: An account of upkeep of hair density after replacing oral Finasteride.
Author: Dr.H.K.Saboowala.
Publisher: Dr.Hakim Saboowala
Total Pages: 32
Release: 2022-11-25
Genre: Medical
ISBN:

“Fortification of Topical Minoxidil with Finasteride”: An account of upkeep of hair density after replacing oral Finasteride. Finasteride reduces DHT level by inhibiting type II 5α reductase, the enzyme responsible for conversion of testosterone to DHT, thereby inhibiting miniaturization of hair follicles. It also promotes the anagen phase of hair growth. Oral intake of finasteride reduces DHT levels in the blood and causes side effects such as decreased libido, erectile dysfunction, etc., Once oral finasteride is stopped, the DHT level rises and reverses its effects, thereby resulting in less dense hair. This accounts for an indefinite period of oral finasteride treatment. Studies show that topical finasteride appears to have results equivalent to oral finasteride in AGA and has better tolerance. Therefore, the study was conducted to assess the efficacy of topical minoxidil fortified with finasteride in the maintenance of hair density post- treatment with oral finasteride. Thus, an attempt has been made in this Booklet to present the evidence base study report comprehensively along with relevant IMAGES and TABLES for better understanding. …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London)

Androgenetic Alopecia From A to Z

Androgenetic Alopecia From A to Z
Author: Konstantinos Anastassakis
Publisher: Springer Nature
Total Pages: 515
Release: 2022-10-26
Genre: Medical
ISBN: 3031080572

This second of three related volumes, designed as a reference tool for the understanding and treatment of Androgenetic Alopecia and Female Pattern Hair Loss (AGA/FPHL), is structured in 4 sections: 63 dedicated chapters covering every aspect of medical (non-surgical, non-invasive) and nutritional treatment options and clinical effects. FDA-approved hair growth drugs, every frequently prescribed "off-label" or experimental drug, hormones, cosmeceuticals, and popular fraudulent controversial products are all presented in 26 chapters, with figures, tables, algorithms, and thousands of fully updated and balanced literature citations. Filling a gap in the latest literature, Androgenetic Alopecia From A to Z: Drugs, Herbs, Nutrition, and Supplements includes a thorough review of lifestyle and nutritional factors specifically affecting AGA/FPHL, including excessive caloric intake, high-fat diets, caloric deprivation, alcohol abuse, and smoking. The intricate effects of nutrition on hair loss, one of the most neglected and misunderstood fields in Dermatology, are presented as well, with a plethora of clinically valuable information: why food supplements are so popular, the regulatory minefield of supplements, and the life-threatening perils of nutritional supplementation, are all reviewed extensively. Each vitamin, major mineral, and trace element implicated in follicular physiology is reviewed in altogether 24 dedicated chapters according to their specific effects on the hair follicle, food sources, dietary recommendations, and the impact of deficiency or excess. This volume includes a comprehensive chapter on the understanding of Complementary-Alternative Medicine (CAM). CAM is an umbrella term for methods that lie outside evidence-based medicine and a part of a societal trend towards the rejection of science as a method of determining facts. The pitfalls and challenges in understanding botanicals with reported hair growth properties, from publication bias to lack of standardization, as well as their unpredictable pharmacological and physiological effects, are all explained in detail. Finally, all popular botanical products reported to possess hair growth properties are appraised in 14 dedicated chapters, each including a detailed review of the general effects, the suggested biochemical mechanisms, claimed actions on the hair follicle, all available studies, and hundreds of literature citations. This carefully crafted book will be an invaluable reference tool for dermatologists and all clinical practitioners dealing with Androgenetic Alopecia and Female Pattern Hair Loss and will help them answer challenging patient questions, debunk myths on hair growth drugs, and supplements and navigate patients towards effective and safe treatment schemes.

Ginseng

Ginseng
Author: Christophe Hano
Publisher: BoD – Books on Demand
Total Pages: 100
Release: 2022-06-15
Genre: Medical
ISBN: 1839690569

Ginseng is the most well-known Chinese medicine as well as one of the most used herbal medicines. It has a wide range of medical and pharmacological uses. This book provides an up-to-date critical view of the botanical description and complexity of ginseng, including its phytochemistry, traditional and biotechnological production systems, traditional usage, current applications, and future directions for the development of ginseng compounds as effective medicinal agents. It is a useful resource for academicians, scientists, students, and industry professionals interested in traditional medicine and ginseng.

IADVL Textbook of Trichology

IADVL Textbook of Trichology
Author: BS Chandrashekar
Publisher: JP Medical Ltd
Total Pages: 585
Release: 2018-06-30
Genre: Medical
ISBN: 935270391X

Trichology is the science of the structure, function and diseases of the human hair. This book is a comprehensive guide to the diagnosis and treatment of diseases and disorders of the hair and scalp. Divided into six sections, the text begins with an overview of hair and the normal scalp, factors controlling hair growth and changes that occur during the aging process. The next section discusses diagnostic trichology methods including microscopy and trichoscopy. The following chapters detail the diagnosis and treatment of numerous hair disorders covering both clinical and surgical procedures, for common and more complex conditions. A chapter on recent advances in surgical management is included. The final section discusses interdisciplinary issues in the management of hair disorders such as paediatric, psychiatric, gynaecologic and endocrinologic liaison therapy. Each chapter begins with a ‘key messages’ box and concludes with a summary of the topic. The book is highly illustrated with clinical photographs, diagrams and tables. Key points Comprehensive guide to the diagnosis and management of diseases and disorders of the hair and scalp Covers both clinical and surgical treatment methods Features discussion on liaison therapy between different medical disciplines Highly illustrated with clinical photographs, diagrams, tables and boxes

From GWAS Hits to Treatment Targets

From GWAS Hits to Treatment Targets
Author: Jeanette Erdmann
Publisher: Frontiers Media SA
Total Pages: 135
Release: 2019-08-16
Genre:
ISBN: 2889459829

Genome-wide association (GWA) studies, as a prototype of large-scale OMICs studies, have advanced our understanding of the genetic basis of many common diseases. With respect to coronary artery disease (CAD) and cardiovascular risk factors, like lipids, blood pressure or BMI, they have identified hundreds of chromosomal loci that modulate disease risk. Despite their scientific success, GWA studies have been criticized for having failed so far in delivering diagnostically or therapeutically relevant products. However, the ability to achieve such goals has been strengthened recently by further layers of OMICs-based data, including large-scale transcriptomics data, and better annotation of regulatory sequences and epigenetic changes in the genome (e.g. through the ENCODE project), as well as novel tools for bioinformatics analysis, allowing a systems medicine based approach to be applied. All in all, the last decade with its “gold rush of genomic discovery” led to the identification of known and novel pathways involved in the pathogenesis of cardiovascular diseases and point to novel treatment targets. This Research Topic has gathered contributions from scientists working in the field of cardiovascular genetics who have common interests in understanding the pathomechanisms linking genetic association findings and disease to finally translate the findings from large-scale genetic studies into novel treatment options.

ACS(I) Textbook on Cutaneous & Aesthetic Surgery

ACS(I) Textbook on Cutaneous & Aesthetic Surgery
Author: Mysore Venkataram
Publisher: JP Medical Ltd
Total Pages: 810
Release: 2017-07-17
Genre: Medical
ISBN: 9352700333

The new edition of this two volume set has been fully revised to provide dermatosurgeons with the latest developments and techniques in the field. The book has been expanded to eighteen sections and 152 chapters, all falling under subspecialties of dermatosurgery, aesthetics, lasers, and practice management. Each technique includes discussion on historical background, indications, contraindications, instrumentation, procedures, adverse effects, complications, and references. The second edition features 81 new chapters on topics such as body shaping, microneedle RF, new laser and energy technologies, platelets rich plasma, regional surgeries, and training in dermatosurgery. The text is enhanced by nearly 2000 clinical photographs and diagrams and also includes text boxes, tables and keynotes in each chapter. Key points Fully revised, second edition of two volume set providing latest techniques in cutaneous and aesthetic surgery Expanded text with 81 new chapters Features nearly 2000 clinical photographs and diagrams Previous edition (9789350258903) published in 2012

Systems of Nanovesicular Drug Delivery

Systems of Nanovesicular Drug Delivery
Author: Amit Kumar Nayak
Publisher: Academic Press
Total Pages: 469
Release: 2022-07-16
Genre: Medical
ISBN: 0323914225

Systems of Nanovesicular Drug Delivery provides a thorough insight into the complete and up-to-date discussions about the preparation, properties and drug delivery applications of various nanovesicles. This volume discusses cubosomes, proniosomes and niosomes, dendrimerosomes and other new and effective approaches for drug delivery. It will be a valuable title and resource for academics and pharmaceutical scientists, including industrial pharmacists, analytical scientists, health care professionals and regulatory scientists actively involved in pharmaceutical products and process development of tailor-made polysaccharides in drug delivery applications. Recently, there have been a number of outstanding nanosystems in nanovesicular carrier-forms (such as nanoemulsions, self-nanoemulsifying systems, nanoliposomes, nanotransferosomes, etc.), that have been researched and developed for efficient drug delivery by many formulators, researchers and scientists. However, no previously published books have covered all these drug delivery nanovesicles collectively in a single resource. - Provides thorough insights and up-to-date discussions about the various systems of nanovesicular drug delivery - Covers advanced trigger-assisted systems (such as iontophoresis, ultra-sound triggering, etc.) and how they have been used for improved drug delivery by nanovesicles - Presents recent advances in drug delivery fields by global leaders and experts from academia, research, industry and regulatory agencies - Includes an updated literature review of relevant key topics, good quality illustrations, chemical structures, attractive flow charts and well-organized tables

Hair Loss and Restoration

Hair Loss and Restoration
Author: Jerry Shapiro
Publisher: CRC Press
Total Pages: 252
Release: 2015-04-17
Genre: Medical
ISBN: 0429586299

Treatment of hair disorders has progressed considerably over time. More patients are now interested in hair care and some are bombarded by promising advertisements. In reality, hair disorders may be complex and require accurate diagnosis for suitable treatment.Hair Loss and Restoration provides an extensive look at the practical management, both me

Hair Transplant 360 (For Assistants), Volume 2

Hair Transplant 360 (For Assistants), Volume 2
Author: Karamanovski Emina
Publisher: Wife Goes On
Total Pages: 148
Release: 2011-06
Genre: Health & Fitness
ISBN: 9789350251799

Hair Transplant 360 is conceived as an entirely new project idea in which the physicians and the assistants have each been afforded an equally, authoritative voice. Volume 2 is written by an assistant for assistants. Phase 1 training (how to train a new assistant and determine whether that individual will perform well using a new “foam model” technique developed by the author). Phase 2 training (how to train an assistant using live tissue after completion of phase 1 training developed by the author). Review of anatomy, physiology and surgery basics for the assistant. Graft preparation: Slivering and graft dissection (step-by-step approach). Managing difficult graft preparation situations: white hair, ethnic hair, scar tissue, etc. Graft placement technique and strategies (step-by-step approach). Understanding regional hair transplant principles (appropriate follicular unit selection and distribution according to their size, hair color and hair characteristics). Understanding the importance of hair curl. Managing difficult graft placement situations: popping, bleeding and oozing. Quality control for the assistant. Office set-up, photography basics, surgery room set-up and take down. Body ergonomics, stress management, team work.

Aging Hair

Aging Hair
Author: Ralph M. Trüeb
Publisher: Springer Science & Business Media
Total Pages: 273
Release: 2010-04-02
Genre: Medical
ISBN: 3642026362

“Aged? But he does not appear aged, just look, his hair has remained young!” Marcel Proust, In Search of Lost Time (1913–27) The appearance of hair plays an important role in peoples’ overall physical appe- ance and self-perception. With today’s increasing life-expectation, the desire to look youthful plays a bigger role than ever. The hair care industry has become aware of this, and capable to deliver active products that are directed toward meeting this c- sumer demand. The discovery of pharmacological targets and the development of safe and effective drugs such as minoxidil and fnasteride also indicate strategies of the drug industry for maintenance of healthy and beautiful hair in the young and old. The study of hair aging focuses on two main streams of interest: On the one hand, the esthetic problem of aging hair and its management, in other words everything that happens outside the skin; on the other hand, the biological problem of aging hair, in terms of microscopic, biochemical, and molecular changes, in other words the “secret life” of the hair follicle in the depth of the skin. Hair aging comprises hair shaft aging, and aging of the hair follicle. The former involves weathering and photoaging of the hair shaft, while the latter manifests as decrease of melanocyte function (graying) and decrease in hair production (alopecia).