Foreign Gene Expression in Fission Yeast: Schizosaccharomyces pombe

Foreign Gene Expression in Fission Yeast: Schizosaccharomyces pombe
Author: Yuko Giga-Hama
Publisher: Springer Science & Business Media
Total Pages: 239
Release: 2013-03-09
Genre: Science
ISBN: 3662034727

Recombinant proteins, produced in cells or microorganisms, play an important role in basic research, medical science and the biotechnology industry. Many foreign gene expression systems using mammalian cells, E. coli, insect cells, yeast and other organisms as hosts have been developed. However, only recently has the expression system of Schizosaccharomyces pombe as a host become a subject of focus, as it is expected to be profitable for expressing foreign genes. The reason for this is that S. pombe is evolutionarily more advanced than other types of yeast. This book describes the use of S. pombe in basic research and industrial applications.

The Molecular Biology of Schizosaccharomyces pombe

The Molecular Biology of Schizosaccharomyces pombe
Author: Richard Egel
Publisher: Springer Science & Business Media
Total Pages: 464
Release: 2013-03-14
Genre: Science
ISBN: 3662103605

The fission yeast Schizosaccharomyces pombe is the favoured tool of many productive research groups throughout the world, serving as a useful model for fundamental principles and mechanisms, such as genome organization, differential gene regulation, cell-cycle control, signal transduction, or cellular morphogenesis. This book collates the current state of knowledge derived from molecular studies in this simple eukaryotic microorganism. The entire sequence of its genome has been completed, emphasizing the comparative value and model status of this yeast. The individual chapters, highlighting up-to-date views on prominent aspects of molecular organization, were written by active research scientists, presenting the results of their investigations to other workers in neighbouring fields. This book intends to serve the fission yeast community as a handy source of reference for years to come. It will also be of particular value to the ever-increasing number of researchers starting to look into fission yeast affairs for comparative reasons from other platforms of molecular genetics and cell biology.

Molecular Biology of the Fission Yeast

Molecular Biology of the Fission Yeast
Author:
Publisher: Elsevier
Total Pages: 482
Release: 2012-12-02
Genre: Nature
ISBN: 0323140068

This highly researched yeast, which represents a system used by cell biologists, geneticists and molecular biologists, has been given only minimal coverage in the literature. Its properties make it an excellent organism for DNA and related biotechnology reseach. This book, which is the first attempt to collate existing information in one source, will be an invaluable aid to those initiating projects with this organism.

Protein Engineering Handbook, Volume 3

Protein Engineering Handbook, Volume 3
Author: Stefan Lutz
Publisher: John Wiley & Sons
Total Pages: 723
Release: 2012-09-14
Genre: Science
ISBN: 3527666982

This introduction collects 17 innovative approaches to engineer novel and improved proteins for diverse applications in biotechnology, chemistry, bioanalytics and medicine. As such, key developments covered in this reference and handbook include de novo enzyme design, cofactor design and metalloenzymes, extremophile proteins, and chemically resistant proteins for industrial processes. The editors integrate academic innovations and industrial applications so as to arrive at a balanced view of this multi-faceted topic. Throughout, the content is chosen to complement and extend the previously published two-volume handbook by the same editors, resulting in a superb overview of this burgeoning field.

The Early Days of Yeast Genetics

The Early Days of Yeast Genetics
Author: Michael N. Hall
Publisher:
Total Pages: 0
Release: 2008
Genre:
ISBN: 9780879698744

Yeast genetics began with Winge's 1935 studies of S. cerevisiae in Copenhagen, and afterwards was pursued by Lindegren in the U.S. and Ephrussi in France. Genetic studies in S. pombe were pioneered by Leupold in the 1940s in Switzerland. Within four decades, not without controversies, both yeast species were recognized as essential models in eukaryotic molecular cell biology. In this remarkable volume, Hall and Linder have assembled the reminiscences of many early investigators whose pioneering studies in the years before 1975 brought yeast biology to its current maturity. These illustrated essays about the science, the events and the personalities involved capture a fascinating era, in the informal style made famous by Phage and the Origins of Molecular Biology. This is a book that all scientists interested in the development of modern genetics and molecular biology should have on their shelves.

Handbook of Copper Pharmacology and Toxicology

Handbook of Copper Pharmacology and Toxicology
Author: Edward J. Massaro
Publisher: Springer Science & Business Media
Total Pages: 600
Release: 2002-07-01
Genre: Medical
ISBN: 1592592880

Edward J. Massaro and a panel of leading biomedical researchers and clinical practitioners review, in-depth, the status of our current knowledge concerning the biochemistry of copper in general and its role in health and disease in particular. Drawing on the wealth of new information emerging from the molecular biology revolution, these experts survey the most important research areas of copper pharmacology and toxicology, including copper proteins and transport, copper toxicity and therapeutics, and copper metabolism and homeostasis. They also discuss the molecular pathogenesis of copper in a variety of metabolic diseases, Menkes and Wilson's diseases and occipital horn syndrome, as well as the role of copper in Parkinson's disease, prion disease, familial amytrophic lateral sclerosis (ALS), and Alzheimer's disease.

Structural Genomics on Membrane Proteins

Structural Genomics on Membrane Proteins
Author: Kenneth H. Lundstrom
Publisher: CRC Press
Total Pages: 401
Release: 2006-02-23
Genre: Medical
ISBN: 1420016083

While the genomic revolution has quickly led to the deposit of more than 30,000 structures in the protein data bank (PDB), less than one percent of those contributions represent membrane proteins despite the fact that membrane proteins constitute some 20 percent of all proteins. This discrepancy becomes significantly troublesome when it is coupled

Biochemical Analysis Tools

Biochemical Analysis Tools
Author: Oana-Maria Boldura
Publisher: BoD – Books on Demand
Total Pages: 207
Release: 2020-06-24
Genre: Science
ISBN: 1789848563

This book explores the role of nucleic acid analysis and the advances it has led to in the field of life sciences. The first section is a collection of chapters covering experimental methods used in molecular biology, the techniques adjacent to these methods, and the steps of analysis before and after obtaining raw DNA data. The second section deals with the principles of chromatography, method development, sample preparation, and industrial applications.

Handbook of Industrial Mycology

Handbook of Industrial Mycology
Author: Zhiqiang An
Publisher: CRC Press
Total Pages: 785
Release: 2004-08-30
Genre: Science
ISBN: 0203970551

Several excellent books have been published that address one or more aspects of the diverse field of industrial mycology, but none of them cover the entire process of fungal bioactive metabolites discovery. Until now. The Handbook of Industrial Mycology provides, in one volume, an overview of recent developments in industrial mycology with emphasis on the discovery of bioactive metabolites and, most importantly, their underlying biology and genetics. Two additional features distinguish this book from other books in the field: 1) most chapters are prepared using experimental data to illustrate theories and 2) the authors provide methodologies and experimental protocols in their chapters. Presenting a comprehensive overview of recent advances, the book provides a framework of basic methods, tools, and organizational principles for channeling fungal germplasm into the academic, pharmaceutical, and enzyme discovery laboratories. It covers the complex range of processes involved in the discovery, characterization, and profiling of bioactive fungal metabolites. The book includes examples of several recently marketed fungal metabolites and explores the impact of fungi on applications in the pharmaceutical, food and beverage, agricultural, and agrochemical industries.