FNA Cytology in the Diagnosis of Lymphoma

FNA Cytology in the Diagnosis of Lymphoma
Author: Lambert Skoog
Publisher: Karger Medical and Scientific Publishers
Total Pages: 89
Release: 2009
Genre: Medical
ISBN: 3805586264

A comprehensive color manual Fine-needle aspiration (FNA) became important for the cytology of the enlarged lymph node in the 1950s and 1960s and was accepted in the diagnosis of various types of lymphadenitis and metastatic disease. The diagnosis of lymphoma by FNA cytology, however, remained controversial for many years, as FNA smears did not allow the evaluation of growth pattern. Only later with the introduction of immunocytochemistry on FNA material it became possible to conclusively diagnose the majority of lymphomas with an accuracy comparable to that of histopathology. Other ancillary techniques such as FISH and PCR can now also be applied successfully to FNA material. These facts together with the excellent clinical performance of FNA sampling should increase the spread of the technique. This comprehensive manual presents the cytomorphologic and immunocytochemical characteristics of both non-Hodgkin and Hodgkin lymphomas. It discusses the technical, methodological aspects of lymphoma diagnosis and describes the cytologic features of reactive lymphoid lesions and the major types of neoplastic lymphoid lesions, based on the most recent (2001) WHO lymphoma classification. Key cytologic and immunologic features are listed to facilitate a conclusive diagnosis of the different lesions. This publication will be of immense value to clinicians such as cytopathologists, pathologists, oncologists, and hematologists involved in the clinical work-up and management of patients with lymph node lesions.

The International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology

The International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology
Author: Andrew S. Field
Publisher: Springer Nature
Total Pages: 190
Release: 2020-02-22
Genre: Medical
ISBN: 3030268837

This text describes a system of reporting breast fine needle aspiration biopsy that uses five clearly defined categories, each described by a specific term and each with a specific risk of malignancy. The five categories are insufficient/inadequate, benign, atypical, suspicious of malignancy and malignant. Each category has a risk of malignancy and is linked to management recommendations, which include several options because it is recognized that diagnostic infrastructure, such as the availability of core needle biopsy and ultrasound guidance, vary between developed and low and middle income countries. This text includes key diagnostic cytological criteria for each of the many lesions and tumors found in the breast. The cytopathology of specific lesions is illustrated with high quality photomicrographs with clear figure descriptions. Chapters also discuss current and potential future ancillary tests, liquid based cytology, nipple cytology and management. An additional chapter provides an overview of an approach to the diagnosis of direct smears of breast fine needle aspiration biopsies. The International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology provides a clear logical approach to the diagnosis and categorization of breast lesions by FNAB cytology, and aims to facilitate communication with breast clinicians, further research into breast cytopathology and related molecular pathology, and improve patient care.

Atlas of Fine Needle Aspiration Cytology

Atlas of Fine Needle Aspiration Cytology
Author: Henryk A. Domanski
Publisher: Springer Science & Business Media
Total Pages: 576
Release: 2013-10-13
Genre: Medical
ISBN: 1447124464

This book covers all of the diagnostic areas where FNAC is used today. This includes palpable lesions and lesions sampled using various radiological methods, and correlations with ancillary examinations detailed on an entity-by-entity basis. As well as being a complete atlas of the facts and findings important to FNAC, this atlas is a guide to diagnostic methods that optimize health care. The interaction of the cytologist or cytopathologist with other specialists (radiologists, oncologists and surgeons) involved in the diagnosis and treatment of patients with suspicious mass lesions is emphasized and illustrated throughout. With contributions from experts in the field internationally and abundant colour images Atlas of Fine Needle Aspiration Cytology provides a comprehensive and up-to-date guide to FNAC for pathologists, cytopathologists, radiologists, oncologists, surgeons and others involved in the diagnosis and treatment of patients with suspicious mass lesions.

Lymph Node Cytopathology

Lymph Node Cytopathology
Author: Stefan E. Pambuccian
Publisher: Springer Science & Business Media
Total Pages: 292
Release: 2010-10-17
Genre: Medical
ISBN: 1441969640

This volume in the Essentials in Cytopathology book series will focus on the cytopathology of lymph nodes. It will address the topic of fine needle aspiration of lymph nodes and fulfill the need for an easy-to-use and authoritative synopsis of lymph node cytopathology. The book with adopt an algorithmic diagnostic approach, starting from the cytomorphologic pattern of the lymph node aspirate. The focus will be on the appropriate and effective use of ancillary studies (immunohistochemistry, flow cytometry, fluorescence in situ hybridization and molecular techniques) and integration of their results into the final diagnosis. The book will present the cytopathologic features and differential diagnoses for the major cytologic patterns in lymph node fine needle aspiration. The entities typically falling within each of these patterns will be discussed with illustration of the spectrum of cytologic features, differential diagnoses and pitfalls. The book will cover the full spectrum of benign and malignant primary conditions of the lymph nodes, with emphasis on common disorders. Discussion of metastatic conditions will be restricted to those that are relevant to the differential diagnosis of primary lymphoid disorders. This book is designed as an easy to use resource that fits into the lab coat pocket, ideal for portability and quick reference. It is heavily illustrated and contains useful algorithms that guide the reader through the differential diagnosis of common and uncommon entities encountered in lymph node aspirates. The accompanying text follows an easy to use pattern-based outline. A useful resource for every pathologist, cytopathologist, fellow and trainee.

The Bethesda System for Reporting Thyroid Cytopathology

The Bethesda System for Reporting Thyroid Cytopathology
Author: Syed Z. Ali
Publisher: Springer Science & Business Media
Total Pages: 257
Release: 2010-03-20
Genre: Medical
ISBN: 0387876669

This atlas is the offspring of the “The National Cancer Institute (NCI) Thyroid Fine Needle Aspiration (FNA) State of the Science Conference,” hosted by the NCI and organized by Dr. Andrea Abati. Preparations for the conference began 18 months earlier with the designation of a steering committee and the establishment of a dedicated, p- manent web site. The meeting took place on October 22 and 23, 2007 in Bethesda, Maryland and was co-moderated by Susan J. Mandel and Edmund S. Cibas. The discussions and conclusions regarding terminology and morphologic criteria 1, 2 from the meeting were summarized in publications by Baloch et al. and form the framework for this atlas. The atlas is organized by the general categories of “Nondiagnostic,” “Benign,” “Follicular Neoplasm/Suspicious for a Follicular Neoplasm”, “Suspicious for Malignancy,” and “Malignant,” and it includes the defi- tions and morphologic criteria of these categories as set forth by Baloch et al. The majority of the conference participants also agreed on a category of “undetermined significance,” which is incorporated in this atlas (Chap. 4). It is critical that the cytopathologist communicate thyroid FNA interpretations to the referring physician in terms that are succinct, unambiguous, and helpful clinically. We recognize that the terminology used here is a flexible framework that can be modified by individual laboratories to meet the needs of their providers and the patients they serve.

Rapid On-site Evaluation (ROSE)

Rapid On-site Evaluation (ROSE)
Author: Guoping Cai
Publisher: Springer Nature
Total Pages: 426
Release: 2019-08-30
Genre: Medical
ISBN: 303021799X

This book introduces basic ROSE techniques and resources required to set up ROSE service. It reviews the cytomorphologic features that are recognizable during ROSE, including those important for sample adequacy, specimen triage, preliminary interpretation, and potential diagnostic pitfalls. Economic and regulatory aspects are discussed as well as the pros and cons of telecytology. The book is formatted for clinical settings, simulating the ROSE process that occurs in the ultrasound room, CT room, bronchoscopy suite, and endoscopy suite. Each chapter focuses on the cytomorphologic clues and pitfalls of the entities specific to that clinical setting. Rapid On-Site Evaluation: A Practical Guide will be a valuable resource for pathologists, cytotechnologists, physicians who perform biopsies and/or ROSE evaluation, and trainees for utilizing ROSE and improving diagnostic performance of biopsies.

Transabdominal Fine-needle Aspiration Biopsy

Transabdominal Fine-needle Aspiration Biopsy
Author: Grace Chia-yu Hsu Yang
Publisher: World Scientific
Total Pages: 486
Release: 2007
Genre: Medical
ISBN: 9812568824

? Over 1,350 illustrations in 350 innovative composite figures designed to teach general pathologists the cytologic approach and cytologists the histologic basis for cytologic criteria? CD-ROM containing high resolution composite images that can be enlarged to the size of computer screen and detailed legends with clinical presentation, cytologic clues with different stains from low to high magnification as well as the mistakes made and lessons learned? Pathologic entities are arranged in the current classifications used by surgical pathologists so that they can translate their experience in histopathology to cytopathology? New classifications of tumors based on advances in cytogenetic and molecular evidence and all new illustrated cases from G C H Yang's collection? A new chapter on gynecologic tumors has been added. The chapter on malignant lymphoma has been completely rewritten to incorporate current WHO classifications. New tumors discovered in the past 16 years and new classifications of adrenal, kidney, liver and pancreatic tumors have been addedThe objective of this book is to share authors' combined 30 years' experience in the fine-needle aspiration biopsy diagnosis of organs beneath the diaphragm with general pathologists. Starting from the basics, this book progresses to in-depth cytomorphologic analysis with histologic and immunohistochemical confirmation of specific entities. Cytohistological correlation is emphasized by using composite images from either resected tumor or the cell block whenever possible. In addition, ultrastructural basis of cytological features is emphasized. Both cytology and electron microscopy classify tumors by meticulously analyzing the cytoplasmic features and cell junctions of scanty sample. Every histopathology entity should have a counterpart in cytopathology, since both derive from the same entity undergoing the same pathological process. The difference is in the artifacts; thus an attempt was made to explain the artifacts of aspiration cytology so that histopathologists may understand the cytologic approach and learn to interpret aspiration cytology with confidence.

Modern Techniques in Cytopathology

Modern Techniques in Cytopathology
Author: M.M. Bui
Publisher: Karger Medical and Scientific Publishers
Total Pages: 120
Release: 2020-01-13
Genre: Medical
ISBN: 3318065765

In the era of precision medicine, physicians are increasingly in need of more definitive diagnostic, prognostic, and predictive information derived from small biopsy specimens such as cytology samples in order to guide effective patient care. Cytopathology is well poised to meet this challenge. Whilst the traditional cytomorphologic component of cytology practice is still valid, enormous advances have been made in the field of cytopathology thanks to transformative technology and innovative individuals that have augmented the cytologists' ability to meet the demands of modern medicine. The purpose of this book is to describe, illustrate, and review many of the most recent developments regarding modern techniques employed in cytopathology. This latest monograph is intended for all cytologists including cytopathologists, cytotechnologists, cytology lab assistants, trainees, research scientists, and anyone who is interested in the field of cytopathology. We have invited pioneering experts in their respective fields to author these chapters. This book is not only the culmination of their groundbreaking work and effort but also presents a critical review of the current literature. We have attempted to provide readers with an informative and comprehensive aid so that they may better appreciate how emerging technology has been applied to cytology. Each chapter in this book presents a stand-alone contemporary review of emerging topics in cytopathology. We hope that you will find this monograph thought-provoking and a valuable reference for your practice.