Fetal Cells In Maternal Blood
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| Author | : Sinuhe Hahn |
| Publisher | : Karger Medical and Scientific Publishers |
| Total Pages | : 145 |
| Release | : 2001-01-01 |
| Genre | : Medical |
| ISBN | : 3805572220 |
Is noninvasive, risk-free prenatal diagnosis of fetal genetic characteristics still a fantasy, or will it soon become reality? The current status of both the leading European research groups as well as the NIH-funded NIFTY study are reported here, indicating that certain fetal genetic traits can now be examined efficiently in a noninvasive manner. Considerable focus is placed on new laser-mediated systems for the effective micro-manipulation of single fetal cells, as well as their analysis by single-cell PCR and the pitfalls to avoid when performing such analyses. Other issues addressed in depth include: novel enrichment techniques, optimal fetal cell recognition, fetal cell culture, as well as the exciting finding that fetal cell traffic is elevated in certain pregnancy-related disorders, most prominently in preeclampsia. This publication is of interest to researchers in the field, genetic counsellors, gynecologists and obstetricians, and researchers in microchimerism, transplantation and transfusion medicine.
| Author | : Yuping Wang |
| Publisher | : Biota Publishing |
| Total Pages | : 126 |
| Release | : 2017-06-23 |
| Genre | : Medical |
| ISBN | : 1615047514 |
The placenta is an organ that connects the developing fetus to the uterine wall, thereby allowing nutrient uptake, waste elimination, and gas exchange via the mother's blood supply. Proper vascular development in the placenta is fundamental to ensuring a healthy fetus and successful pregnancy. This book provides an up-to-date summary and synthesis of knowledge regarding placental vascular biology and discusses the relevance of this vascular bed to the functions of the human placenta.
| Author | : Joe Leigh Simpson |
| Publisher | : |
| Total Pages | : 296 |
| Release | : 1994 |
| Genre | : Health & Fitness |
| ISBN | : |
Several lines of evidence indicate that foetal cells - lymphocytes, nucleated red cells, trophoblasts - exist in maternal blood during pregnancy. The potential thus exists for recovering foetal cells from maternal blood and then analysing these cells for foetal genetic abnormalities. This volume explores the biology and maternal foetal transfer of the three cell types during pregnancy, the use of flow cytometry and other techniques to enrich the yield of these cells from maternal blood, the application of diagnostic techniques for identifying cytogenetic and other genetic abnormalities, and public health and other issues involved in the implementation of such testing.
| Author | : S. Hahn |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2001 |
| Genre | : Medical |
| ISBN | : 9783318006995 |
Is noninvasive, risk-free prenatal diagnosis of fetal genetic characteristics still a fantasy, or will it soon become reality? The current status of both the leading European research groups as well as the NIH-funded NIFTY study are reported here, indicating that certain fetal genetic traits can now be examined efficiently in a noninvasive manner. Considerable focus is placed on new laser-mediated systems for the effective micro-manipulation of single fetal cells, as well as their analysis by single-cell PCR and the pitfalls to avoid when performing such analyses. Other issues addressed in depth include: novel enrichment techniques, optimal fetal cell recognition, fetal cell culture, as well as the exciting finding that fetal cell traffic is elevated in certain pregnancy-related disorders, most prominently in preeclampsia. This publication is of interest to researchers in the field, genetic counsellors, gynecologists and obstetricians, and researchers in microchimerism, transplantation and transfusion medicine.
| Author | : Yuk-Ming Dennis Lo |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 1994 |
| Genre | : Fetal cells from maternal blood |
| ISBN | : |
| Author | : Anthony Atala |
| Publisher | : Academic Press |
| Total Pages | : 438 |
| Release | : 2018-06-14 |
| Genre | : Medical |
| ISBN | : 0128120630 |
Perinatal Stem Cells provides researchers and clinicians with a comprehensive description of the current clinical and pre-clinical applications of stem cells derived from perinatal sources, such as amniotic fluid, placenta and placental membranes, the umbilical cord and Wharton’s jelly. It's compiled by leading experts in the field, offering readers detailed insights into sources of perinatal stem cells and their potential for disease treatment. Therapeutic applications of perinatal stem cells include the treatment of in utero and pregnancy related diseases, cardiac disease, liver disease, pulmonary disease, inflammatory diseases, for hematopoietic regeneration, and for neural protection after stroke or traumatic brain injury. In addition, the rapid advance in clinical translation and commercialization of perinatal stem cell therapies is highlighted in a section on Clinical and Industry Perspective which provides insight into the new opportunities and challenges involved in this novel and exciting industry. Explores current clinical and pre-clinical application of stem cells derived from perinatal sources Offers detailed insight into sources of perinatal stem cells and their potential for disease treatment Discusses progress in the manufacturing, banking and clinical translation of perinatal stem cells Edited by a world-renowned team to present a complete story of the development and promise of perinatal stem cells
| Author | : Raymond W. Redline |
| Publisher | : Cambridge University Press |
| Total Pages | : 367 |
| Release | : 2018-08-23 |
| Genre | : Medical |
| ISBN | : 1316632539 |
A guide to identifying disease processes in the placenta affecting pregnancy outcome, with current diagnostic criteria and clinical consequences.
| Author | : Laura Dean |
| Publisher | : |
| Total Pages | : |
| Release | : 2005 |
| Genre | : Blood group antigens |
| ISBN | : |
| Author | : Maria Wilhelmina Johanna Christina Jansen |
| Publisher | : |
| Total Pages | : 145 |
| Release | : 2000 |
| Genre | : |
| ISBN | : 9789056770440 |
| Author | : Anthony Carter |
| Publisher | : Boydell & Brewer |
| Total Pages | : 456 |
| Release | : 1998 |
| Genre | : Maternal-fetal exchange |
| ISBN | : 9781580460439 |
The 29 papers contained in this volume look closely at various aspects of what is termed, "The Maternal-Fetal Interface," as it relates to the latest research in placental science. A substantial section of the book is devoted to the troublesome question of vertical transmission of infectious agents: namely, the HIV-1 virus. However, other sections of the volume examine related issues such as drug and toxin transfer across the term placenta and the diversity of placental types and how this can affect a placenta's effectiveness as a barrier. Anthony Carter is at the University of Odense, Denmark Vibeke Dantzer is at the University of Copenhagen, DenmarkThomas Jansson is at the University of Gothenburg, Sweden
