Apoptosis and Beyond

Apoptosis and Beyond
Author: James A. Radosevich
Publisher: John Wiley & Sons
Total Pages: 768
Release: 2018-09-18
Genre: Science
ISBN: 1119432359

These volumes teach readers to think beyond apoptosis and describes all of the known processes that cells can undergo which result in cell death This two-volume source on how cells dies is the first, comprehensive collection to cover all of the known processes that cells undergo when they die. It is also the only one of its kind to compare these processes. It seeks to enlighten those in the field about these many processes and to stimulate their thinking at looking at these pathways when their research system does not show signs of activation of the classic apoptotic pathway. In addition, it links activities like the molecular biology of one process (eg. Necrosis) to another process (eg. apoptosis) and contrasts those that are close to each. Volume 1 of Apoptosis and Beyond: The Many Ways Cells Die begins with a general view of the cytoplasmic and nuclear features of apoptosis. It then goes on to offer chapters on targeting the cell death mechanism; microbial programmed cell death; autophagy; cell injury, adaptation, and necrosis; necroptosis; ferroptosis; anoikis; pyronecrosis; and more. Volume 2 covers such subjects as phenoptosis; pyroptosis; hematopoiesis and eryptosis; cyclophilin d-dependent necrosis; and the role of phospholipase in cell death. Covers all known processes that dying cells undergo Provides extensive coverage of a topic not fully covered before Offers chapters written by top researchers in the field Provides activities that link and contrast processes to each other Apoptosis and Beyond: The Many Ways Cells Die will appeal to students and researchers/clinicians in cell biology, molecular biology, oncology, and tumor biology.

Beyond the Magic Bullet

Beyond the Magic Bullet
Author: Raymond Chang
Publisher: Square One Publishers, Inc.
Total Pages: 245
Release: 2012-05-17
Genre: Health & Fitness
ISBN: 0757052320

While scientists win occasional skirmishes in the battle against cancer, the overall war continues to go badly. Stories abound about revolutionary drugs that may be available in the future, but offer no real help to those who have cancer today. At present, conventional approaches continue to rely on a narrowly focused strategy of treatments, with doctors using, at best, only one or two drugs or other therapies at a time. While this may be acceptable in a laboratory setting or a clinical trial, it has done little to diminish the number of people who die each year from this dread disease. Recently, however, conventional medicine’s core strategy has been re-examined, and a new, potentially more effective approach has emerged—one that combines the best of Eastern wisdom with Western science. Beyond the Magic Bullet—The Anti-Cancer Cocktail by Dr. Raymond Chang takes a penetrating look at this bold new way of treating cancer. The book begins by examining modern medicine’s use of surgery, radiation, chemotherapy, hormone therapy, and targeted drugs in the war against cancer. It then offers a new therapy based on the knowledge that certain off-label drugs, nutrients, and therapies are each somewhat effective against cancer. By combining these therapeutic agents into a “cocktail,” doctors have found that they can attack the cancer all at once, on many different levels and at several different angles, with the goal of overwhelming the disease. Dr. Chang not only discusses the effectiveness of the cocktail, but also provides an examination of the most valuable agents available. For over a thousand years, Traditional Chinese Medicine has used the cocktail approach to safely and effectively fight disease. Throughout the world, the most successful treatments for HIV and Hepatitis C are based on this strategy. Beyond the Magic Bullet—The Anti-Cancer Cocktail leads the way to a bright new future of hope and healing.

Apoptosis and Beyond, 2 Volume Set

Apoptosis and Beyond, 2 Volume Set
Author: James A. Radosevich
Publisher: John Wiley & Sons
Total Pages: 784
Release: 2018-12-27
Genre: Science
ISBN: 1119432421

These volumes teach readers to think beyond apoptosis and describes all of the known processes that cells can undergo which result in cell death This two-volume source on how cells dies is the first, comprehensive collection to cover all of the known processes that cells undergo when they die. It is also the only one of its kind to compare these processes. It seeks to enlighten those in the field about these many processes and to stimulate their thinking at looking at these pathways when their research system does not show signs of activation of the classic apoptotic pathway. In addition, it links activities like the molecular biology of one process (eg. Necrosis) to another process (eg. apoptosis) and contrasts those that are close to each. Volume 1 of Apoptosis and Beyond: The Many Ways Cells Die begins with a general view of the cytoplasmic and nuclear features of apoptosis. It then goes on to offer chapters on targeting the cell death mechanism; microbial programmed cell death; autophagy; cell injury, adaptation, and necrosis; necroptosis; ferroptosis; anoikis; pyronecrosis; and more. Volume 2 covers such subjects as phenoptosis; pyroptosis; hematopoiesis and eryptosis; cyclophilin d-dependent necrosis; and the role of phospholipase in cell death. Covers all known processes that dying cells undergo Provides extensive coverage of a topic not fully covered before Offers chapters written by top researchers in the field Provides activities that link and contrast processes to each other Apoptosis and Beyond: The Many Ways Cells Die will appeal to students and researchers/clinicians in cell biology, molecular biology, oncology, and tumor biology.

Cell Death

Cell Death
Author: Douglas R. Green
Publisher:
Total Pages: 0
Release: 2018
Genre: Science
ISBN: 9781621822141

A million cells in our bodies die every second--they commit suicide by activating a process called apoptosis or other forms of programmed cell death. These mechanisms are essential for survival of the body as a whole and play critical roles in various developmental processes, the immune system, and cancer. In this second edition of Douglas Green's essential book on cell death, Green retains the bottom-up approach of the first edition, starting with the enzymes that carry out the execution (caspases) and their cellular targets before examining the machinery that connects them to signals that cause cell death. He also describes the roles of cell death in development, neuronal selection, and the development of self-tolerance in the immune system, as well as how the body uses cell death to defend against cancer. The new edition is fully updated to cover the many recent advances in our understanding of the death machinery and signals that control cell death. These include the mechanisms regulating necroptosis, mitophagy, and newly identified processes, such as ferroptosis. The book will thus be of great interest to researchers actively working in the field, as well as biologists and undergraduates encountering the topic for the first time.

Proton and Carbon Ion Therapy

Proton and Carbon Ion Therapy
Author: C-M Charlie Ma
Publisher: CRC Press
Total Pages: 258
Release: 2012-10-09
Genre: Science
ISBN: 1439816077

Proton and Carbon Ion Therapy is an up-to-date guide to using proton and carbon ion therapy in modern cancer treatment. The book covers the physics and radiobiology basics of proton and ion beams, dosimetry methods and radiation measurements, and treatment delivery systems. It gives practical guidance on patient setup, target localization, and treatment planning for clinical proton and carbon ion therapy. The text also offers detailed reports on the treatment of pediatric cancers, lymphomas, and various other cancers. After an overview, the book focuses on the fundamental aspects of proton and carbon ion therapy equipment, including accelerators, gantries, and delivery systems. It then discusses dosimetry, biology, imaging, and treatment planning basics and provides clinical guidelines on the use of proton and carbon ion therapy for the treatment of specific cancers. Suitable for anyone involved with medical physics and radiation therapy, this book offers a balanced and critical assessment of state-of-the-art technologies, major challenges, and the future outlook of proton and carbon ion therapy. It presents a thorough introduction for those new to the field while providing a helpful, up-to-date reference for readers already using the therapy in clinical settings.

Life Over Cancer

Life Over Cancer
Author: Keith Block
Publisher: Bantam
Total Pages: 610
Release: 2009-04-21
Genre: Health & Fitness
ISBN: 0553801147

Dr. Keith Block is at the global vanguard of innovative cancer care. As medical director of the Block Center for Integrative Cancer Treatment in Evanston, Illinois, he has treated thousands of patients who have lived long, full lives beyond their original prognoses. Now he has distilled almost thirty years of experience into the first book that gives patients a systematic, research-based plan for developing the physical and emotional vitality they need to meet the demands of treatment and recovery. Based on a profound understanding of how body and mind can work together to defeat disease, this groundbreaking book offers: • Innovative approaches to conventional treatments, such as “chronotherapy”–chemotherapy timed to patients’ unique circadian rhythms for enhanced effectiveness and reduced toxicity • Dietary choices that make the biochemical environment hostile to cancer growth and recurrence, and strengthen the immune system’s ability to attack remaining cancer cells • Precise supplement protocols to tame treatment side effects, relieve disease-related symptoms, and modify processes like inflammation and glycemia that can fuel cancer if left untreated • A new paradigm for exercise and stress reduction that restores your strength, reduces anxiety and depression, and supports the body’s own ability to heal • A complete program for remission maintenance–a proactive plan to make sure the cancer never returns Also included are “quick-start” maps to help you find the information you need right now and many case histories that will support and inspire you. Encouraging, compassionate, and authoritative, Life over Cancer is the guide patients everywhere have been waiting for.

Never Fear Cancer Again

Never Fear Cancer Again
Author: Raymond Francis
Publisher: Health Communications, Inc.
Total Pages: 386
Release: 2011-08-01
Genre: Health & Fitness
ISBN: 075731550X

Most cancer research dollars have been wasted by asking the wrong questions, looking in the wrong places, and recycling the same failed approaches while expecting different results. Conventional cancer treatments damage health, cause new cancers, lower the quality of life, and decrease the chances of survival. In fact, most people who die from cancer are not dying from cancer, but from their treatments! That's the bad news. Here's the good news: We can end the cancer epidemic. In Never Fear Cancer Again, readers will gain a revolutionary new understanding of health and disease and will come to understand that cancer is a biological process that can be turned on and off, not something that can be surgically removed or destroyed with radiation or toxic chemicals. So whether cancer has already been diagnosed or if prevention is the concern, it is possible to turn off the wayward production of these malfunctioning cells once and for all by reading this book and implementing its strategies. The key to any disease has one simple cause: malfunctioning cells that are created by either deficiency or toxicity. By switching off the malfunctioning cells, you switch off the cancer. Never Fear Cancer Again guides readers along six pathways that cause deficiency or toxicity at the cellular level: nutritional path, genetic path, medical path, toxin path, physical path, and the psychological path. By making key lifestyle changes, people truly have the power to take control of cancer and transform their health. This radically different, yet holistic approach restored author Raymond Francis back to health just as it has helped thousands of others, many of whom were told they had no other options or that their cancer was incurable. Take back your health with this book and never fear cancer again.

The Metabolic Approach to Cancer

The Metabolic Approach to Cancer
Author: Nasha Winters
Publisher: Chelsea Green Publishing
Total Pages: 409
Release: 2017
Genre: Cancer
ISBN: 1603586865

The Optimal Terrain Ten Protocol to Reboot Cellular Health Since the beginning of the twentieth century, cancer rates have increased exponentially--now affecting almost 50 percent of the American population. Conventional treatment continues to rely on chemotherapy, surgery, and radiation to attack cancer cells. Yet research has repeatedly shown that 95 percent of cancer cases are directly linked to diet and lifestyle. The Metabolic Approach to Cancer is the book we have been waiting for--it offers an innovative, metabolic-focused nutrition protocol that actually works. Naturopathic, integrative oncologist and cancer survivor Dr. Nasha Winters and nutrition therapist Jess Higgins Kelley have identified the ten key elements of a person's "terrain" (think of it as a topographical map of our body) that are crucial to preventing and managing cancer. Each of the terrain ten elements--including epigenetics, the microbiome, the immune system, toxin exposures, and blood sugar balance--is illuminated as it relates to the cancer process, then given a heavily researched and tested, non-toxic and metabolic, focused nutrition prescription. The metabolic theory of cancer--that cancer is fueled by high carbohydrate diets, not "bad" genetics--was introduced by Nobel Prize-laureate and scientist Otto Warburg in 1931. It has been largely disregarded by conventional oncology ever since. But this theory is resurging as a result of research showing incredible clinical outcomes when cancer cells are deprived of their primary fuel source (glucose). The ketogenic diet--which relies on the body's production of ketones as fuel--is the centerpiece of The Metabolic Approach to Cancer. Further, Winters and Kelley explain how to harness the anticancer potential of phytonutrients abundant in low-glycemic plant and animal foods to address the 10 hallmarks of cancer--an approach Western medicine does with drug based therapies. Their optimized, genetically-tuned diet shuns grains, legumes, sugar, genetically modified foods, pesticides, and synthetic ingredients while emphasizing whole, wild, local, organic, fermented, heirloom, and low-glycemic foods and herbs. Other components of their approach include harm-reductive herbal therapies like mistletoe (considered the original immunotherapy and common in European cancer care centers) and cannabinoids (which shrink tumors and increase quality of life, yet are illegal in more than half of the United States). Through addressing the ten root causes of cancer and approaching the disease from a nutrition-focused standpoint, we can slow cancer's endemic spread and live optimized lives.