Fate and Effects of Anticancer Drugs in the Environment

Fate and Effects of Anticancer Drugs in the Environment
Author: Ester Heath
Publisher: Springer Nature
Total Pages: 472
Release: 2020-01-01
Genre: Science
ISBN: 3030210480

The book provides current knowledge and research on the presence and effects of anticancer drug residues in the aqueous environment and covers all relevant aspects of the presence of these residues in wastewaters and natural aquatic systems, where numerous analogies between their pharmacokinetics and pharmacodynamics in humans and their effects in the environment can be drawn. This book comprises of 18 chapters and represents the combined work of leading scientists from different research institutions from across the globe. We present the state of the art in the field of anticancer drug residues in the aquatic environment while being cognizant of the many challenges that remain.

Pharmaceutical Residues in Freshwater: Hazards and Policy Responses

Pharmaceutical Residues in Freshwater: Hazards and Policy Responses
Author: Organisation for Economic Co-Operation and Development (OECD)
Publisher: IWA Publishing
Total Pages: 138
Release: 2020-07-15
Genre: Science
ISBN: 1789061814

This report calls for a better understanding of the effects of pharmaceutical residues in the environment, greater international collaboration and accountability distribution, and policy actions to prevent and remedy emerging concerns. Laboratory and field tests show traces of oral contraceptives causing the feminisation of fish and amphibians, and residues of psychiatric drugs altering fish behaviour. Antimicrobial resistance, linked to the overuse of antibiotics, has rapidly escalated into a global health crisis. Unless adequate measures are taken to manage the risks, pharmaceutical residues will increasingly be released into the environment as ageing populations, advances in healthcare, and intensification of meat and fish production spur the demand for pharmaceuticals worldwide. The report outlines a collective, life‑cycle approach to managing pharmaceuticals in the environment. A policy mix of source‑directed, use‑orientated and end‑of‑pipe measures, involving several policy sectors, can help to improve health and protect the environment.

Hospital Wastewaters

Hospital Wastewaters
Author: Paola Verlicchi
Publisher: Springer
Total Pages: 254
Release: 2017-09-04
Genre: Technology & Engineering
ISBN: 3319621785

This volume addresses hospital effluents in terms of their composition and the management and treatment strategies currently (being) adopted around the globe. In this context, one major focus is on pharmaceutical compounds: their observed concentration range, ecotoxicological effects, and the removal efficiency achieved by the different technologies. Another focus is on management strategies (dedicated hospital wastewater treatment, or a combined approach also involving urban wastewater) and currently adopted treatments to reduce the released pollutant load. Innovative and promising technologies under investigation at the lab and pilot scale are presented. A discussion of remaining knowledge gaps and future research requirements rounds out the coverage. The respective chapters, written by experts in the different fields, provide useful information for a broad audience: scientists involved in the management and treatment of hospital effluents and wastewater containing micropollutants, administrators and decision-makers, legislators involved in the authorization and management of healthcare structure effluents, and environmental engineers involved in the design of wastewater treatment plants, as well as newcomers and students interested in these issues.

Management of Contaminants of Emerging Concern (CEC) in Environment

Management of Contaminants of Emerging Concern (CEC) in Environment
Author: Pardeep Singh
Publisher: Elsevier
Total Pages: 468
Release: 2021-03-12
Genre: Technology & Engineering
ISBN: 0128222646

Management of Contaminants of Emerging Concern (CEC) in Environment provides information about new concepts and latest developments in origin, reaction pathways, transportation, transformation products, identification, and adverse effects of CEC, as well as recent remediation technologies and tools for CEC. The book explores processes such as nanotechnology for the degradation of CEC by using various heterogeneous catalysts. The chapters incorporate both theoretical and practical aspects and can serve as a baseline for future studies. So, Management of Contaminants of Emerging Concern (CEC) in Environment is an indispensable resource for university students, teachers, and researchers, especially those working in the area of remediation and management of contaminants of emerging concern. Takes a holistic approach, focusing on the origin of contaminants, type of contaminants, remediation technologies, regulations and legal aspects Applies chemical, physical and biological processes for the treatment of emerging contaminants Written by a team of internationally reputed and rising researchers

The Undying

The Undying
Author: Anne Boyer
Publisher: Farrar, Straus and Giroux
Total Pages: 320
Release: 2019-09-17
Genre: Biography & Autobiography
ISBN: 0374719489

WINNER OF THE 2020 PULITZER PRIZE IN GENERAL NONFICTION "The Undying is a startling, urgent intervention in our discourses about sickness and health, art and science, language and literature, and mortality and death. In dissecting what she terms 'the ideological regime of cancer,' Anne Boyer has produced a profound and unforgettable document on the experience of life itself." —Sally Rooney, author of Normal People "Anne Boyer’s radically unsentimental account of cancer and the 'carcinogenosphere' obliterates cliche. By demonstrating how her utterly specific experience is also irreducibly social, she opens up new spaces for thinking and feeling together. The Undying is an outraged, beautiful, and brilliant work of embodied critique." —Ben Lerner, author of The Topeka School A week after her forty-first birthday, the acclaimed poet Anne Boyer was diagnosed with highly aggressive triple-negative breast cancer. For a single mother living paycheck to paycheck who had always been the caregiver rather than the one needing care, the catastrophic illness was both a crisis and an initiation into new ideas about mortality and the gendered politics of illness. A twenty-first-century Illness as Metaphor, as well as a harrowing memoir of survival, The Undying explores the experience of illness as mediated by digital screens, weaving in ancient Roman dream diarists, cancer hoaxers and fetishists, cancer vloggers, corporate lies, John Donne, pro-pain ”dolorists,” the ecological costs of chemotherapy, and the many little murders of capitalism. It excoriates the pharmaceutical industry and the bland hypocrisies of ”pink ribbon culture” while also diving into the long literary line of women writing about their own illnesses and ongoing deaths: Audre Lorde, Kathy Acker, Susan Sontag, and others. A genre-bending memoir in the tradition of The Argonauts, The Undying will break your heart, make you angry enough to spit, and show you contemporary America as a thing both desperately ill and occasionally, perversely glorious. Includes black-and-white illustrations

How Tobacco Smoke Causes Disease

How Tobacco Smoke Causes Disease
Author: United States. Public Health Service. Office of the Surgeon General
Publisher:
Total Pages: 728
Release: 2010
Genre: Government publications
ISBN:

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Handbook of Anticancer Drugs from Marine Origin

Handbook of Anticancer Drugs from Marine Origin
Author: Se-Kwon Kim
Publisher: Springer
Total Pages: 801
Release: 2014-11-27
Genre: Science
ISBN: 3319071459

This timely desk reference focuses on marine-derived bioactive substances which have biological, medical and industrial applications. The medicinal value of these marine natural products are assessed and discussed. Their function as a new and important resource in novel, anticancer drug discovery research is also presented in international contributions from several research groups. For example, the potential role of Spongistatin, Apratoxin A, Eribulin mesylate, phlorotannins, fucoidan, as anticancer agents is explained. The mechanism of action of bioactive compounds present in marine algae, bacteria, fungus, sponges, seaweeds and other marine animals and plants are illustrated via several mechanisms. In addition, this handbook lists various compounds that are active candidates in chemoprevention and their target actions. The handbook also places into context the demand for anticancer nutraceuticals and their use as potential anti-cancer pharmaceuticals and medicines. This study of advanced and future types of natural compounds from marine sources is written to facilitate the understanding of Biotechnology and its application to marine natural product drug discovery research.

Development in Wastewater Treatment Research and Processes

Development in Wastewater Treatment Research and Processes
Author: Maulin P Shah
Publisher: Elsevier
Total Pages: 464
Release: 2024-01-13
Genre: Technology & Engineering
ISBN: 032399279X

Development in Wastewater Treatment Research and Processes: Innovative Trends in Removal of Refractory Pollutants from Pharmaceutical Waste Water sorts out emerging and burning issues faced by the pharmaceutical industry, along with common effluent treatment plans. The book provides a comprehensive view of recent advents of various novel, advanced and hybrid treatment technologies in pharmaceutical wastewater treatment to treat emerging pollutants released by the pharmaceutical industry in their untreated wastewater. In addition, the book gives insights into recent developments with a physico-chemical and microbiological focus on the treatment of emerging contaminants (pollutants) present in pharmaceutical wastewater. Discusses fundamentals of physico-chemical and microbiological wastewater treatment systems, advantages, limitations and promising solutions of different types of emerging contaminants present in pharmaceutical wastewater Presents recent trends and developments in the removal of refractory organics (pollutants/contaminants) from pharmaceutical wastewater for achieving sustainable wastewater treatment Covers applications of various advanced and hybrid treatment technologies for the removal of emerging contaminants from pharmaceutical wastewater treatment plants Includes hybrid treatment technologies, their design and application in the removal of pharmaceutical wastewater contaminants Addresses challenges for the full-scale implementation of bioreactors for pharmaceutical wastewater treatment