Experimentation with Human Beings

Experimentation with Human Beings
Author: Jay Katz
Publisher: Russell Sage Foundation
Total Pages: 1210
Release: 1972-07-24
Genre: Psychology
ISBN: 1610448340

In recent years, increasing concern has been voiced about the nature and extent of human experimentation and its impact on the investigator, subject, science, and society. This casebook represents the first attempt to provide comprehensive materials for studying the human experimentation process. Through case studies from medicine, biology, psychology, sociology, and law—as well as evaluative materials from many other disciplines—Dr. Katz examines the problems raised by human experimentation from the vantage points of each of its major participants—investigator, subject, professions, and state. He analyzes what kinds of authority should be delegated to these participants in the formulation, administration, and review of the human experimentation process. Alternative proposals, from allowing investigators a completely free hand to imposing centralized governmental control, are examined from both theoretical and practical perspectives. The conceptual framework of Experimentation with Human Beings is designed to facilitate not only the analysis of such concepts as "harm," "benefit," and "informed consent," but also the exploration of the problems raised by man's quest for knowledge and mastery, his willingness to risk human life, and his readiness to delegate authority to professionals and rely on their judgment.

The Uses of Humans in Experiment

The Uses of Humans in Experiment
Author:
Publisher: BRILL
Total Pages: 309
Release: 2016-03-11
Genre: Science
ISBN: 9004286713

Scientific experimentation with humans has a long history. Combining elements of history of science with history of medicine, The Uses of Humans in Experiment illustrates how humans have grappled with issues of consent, and how scientists have balanced experience with empiricism to achieve insights for scientific as well as clinical progress. The modern incarnation of ethics has often been considered a product of the second half of the twentieth century, as enshrined in international laws and codes, but these authors remind us that this territory has long been debated, considered, and revisited as a fundamental part of the scientific enterprise that privileges humans as ideal subjects for advancing research.

Experimenting with Humans and Animals

Experimenting with Humans and Animals
Author: Anita Guerrini
Publisher: JHU Press
Total Pages: 198
Release: 2003-07-02
Genre: History
ISBN: 9780801871979

Ethical questions about the use of animals and humans in research remain among the most vexing within both the scientific community and society at large. These often rancorous arguments have gone on, however, with little awareness of their historical antecedents. Experimentation on animals and particularly humans is often assumed to be a uniquely modern phenomenon, but the ideas and attitudes that encourage the biological and medical sciences to experiment on living creatures date from the earliest expression of Western thought. Here, Anita Guerrini looks at the history of these practices from vivisection in ancient Alexandria to present-day battles over animal rights and medical research employing human subjects. Guerrini discusses key historical episodes, including the discovery of blood circulation, the development of smallpox and polio vaccines, and recent AIDS research. She also explores the rise of the antivivisection movement in Victorian England, the modern animal rights movement, and current debates over gene therapy.--From publisher description.

Subjected to Science

Subjected to Science
Author: Susan E. Lederer
Publisher: JHU Press
Total Pages: 226
Release: 1997-11-07
Genre: History
ISBN: 9780801857096

Susan Lederer provides the first full-length history of early biomedical research with human subjects. Lederer offers detailed accounts of experiments conducted on both healthy and unhealthy men, women, and children, during the period from 1890 to 1940, including yellow fever experiments, Udo Wile's "dental drill" experiments on insane patients, and Hideyo Noguchi's syphilis experiments.

For the Good of Mankind?

For the Good of Mankind?
Author: Vicki Oransky Wittenstein
Publisher: Twenty-First Century Books
Total Pages: 100
Release: 2013-10-01
Genre: Juvenile Nonfiction
ISBN: 1467706590

Experiment: A child is deliberately infected with the deadly smallpox disease without his parents' informed consent. Result: The world's first vaccine. Experiment: A slave woman is forced to undergo more than thirty operations without anesthesia. Result: The beginnings of modern gynecology. Incidents like these paved the way for crucial, lifesaving medical discoveries. But they also harmed and humiliated their test subjects, many of whom did not agree to the experiments in the first place. How do doctors balance the need to test new medicines and procedures with their ethical duty to protect the rights of human subjects? Take a harrowing journey through some of history's greatest medical advances?and its most horrifying medical atrocities?to discover how human suffering has gone hand in hand with medical advancement.

The Use of Human Beings in Research

The Use of Human Beings in Research
Author: S.F. Spicker
Publisher: Springer Science & Business Media
Total Pages: 301
Release: 2012-12-06
Genre: Medical
ISBN: 9400927053

This volume, which has developed from the Fourteenth Trans Disciplinary Symposium on Philosophy and Medicine, September 5-8, 1982, at Tel Aviv University, Israel, contains the contributions of a group of distinguished scholars who together examine the ethical issues raised by the advance of biomedical science and technology. We are, of course, still at the beginning of a revolution in our understanding of human biology; scientific medicine and clinical research are scarcely one hundred years old. Both the sciences and the technology of medicine until ten or fifteen years ago had the feeling of the 19th century about them; we sense that they belonged to an older time; that era is ending. The next twenty-five to fifty years of investigative work belong to neurobiology, genetics, and reproductive biology. The technologies of information processing and imaging will make diagnosis and treatment almost incomprehensible by my generation of physicians. Our science and technology will become so powerful that we shall require all of the art and wisdom we can muster to be sure that they remain dedicated, as Francis Bacon hoped four centuries ago, "to the uses of life." It is well that, as philosophers and physicians, we grapple with the issues now when they are relatively simple, and while the pace of change is relatively slow. We require a strategy for the future; that strategy must be worked out by scientists, philosophers, physicians, lawyers, theologians, and, I should like to add, artists and poets.

The Human Experiment

The Human Experiment
Author: Jane Poynter
Publisher: Basic Books
Total Pages: 384
Release: 2006-08-18
Genre: Science
ISBN: 9781560257752

It's a story that has never been told … until now. Imagine being sealed into a closed environment for two years — cut off from the outside world with only seven other people — enduring never-ending hunger, severely low levels of oxygen, and extremely difficult relationships. Crew members struggled to survive in Biosphere 2, where they swore nothing would go in or out — no food or water, not even air — all in the name of science. For the first time, biospherian Jane Poynter — who lived and loved in the Biosphere — is ready to share what really happened in there. She takes readers on a riveting, fast-paced trip through shattered lives, scientific discovery, cults, love, fears of insanity, and inspiring human endurance. The eight biospherians who closed themselves into the Biosphere emerged 730 days later… much wiser, thinner, and having done what many had said was impossible.

Use of Laboratory Animals in Biomedical and Behavioral Research

Use of Laboratory Animals in Biomedical and Behavioral Research
Author: National Research Council
Publisher: National Academies Press
Total Pages: 113
Release: 1988-02-01
Genre: Science
ISBN: 0309038391

Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.