The Threat of Pandemic Influenza

The Threat of Pandemic Influenza
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 431
Release: 2005-04-09
Genre: Medical
ISBN: 0309095042

Public health officials and organizations around the world remain on high alert because of increasing concerns about the prospect of an influenza pandemic, which many experts believe to be inevitable. Moreover, recent problems with the availability and strain-specificity of vaccine for annual flu epidemics in some countries and the rise of pandemic strains of avian flu in disparate geographic regions have alarmed experts about the world's ability to prevent or contain a human pandemic. The workshop summary, The Threat of Pandemic Influenza: Are We Ready? addresses these urgent concerns. The report describes what steps the United States and other countries have taken thus far to prepare for the next outbreak of "killer flu." It also looks at gaps in readiness, including hospitals' inability to absorb a surge of patients and many nations' incapacity to monitor and detect flu outbreaks. The report points to the need for international agreements to share flu vaccine and antiviral stockpiles to ensure that the 88 percent of nations that cannot manufacture or stockpile these products have access to them. It chronicles the toll of the H5N1 strain of avian flu currently circulating among poultry in many parts of Asia, which now accounts for the culling of millions of birds and the death of at least 50 persons. And it compares the costs of preparations with the costs of illness and death that could arise during an outbreak.

Flu

Flu
Author: Gina Kolata
Publisher: Farrar, Straus and Giroux
Total Pages: 378
Release: 2011-04-01
Genre: Social Science
ISBN: 1429979356

Veteran journalist Gina Kolata's Flu: The Story of the Great Influenza Pandemic of 1918 and the Search for the Virus That Caused It presents a fascinating look at true story of the world's deadliest disease. In 1918, the Great Flu Epidemic felled the young and healthy virtually overnight. An estimated forty million people died as the epidemic raged. Children were left orphaned and families were devastated. As many American soldiers were killed by the 1918 flu as were killed in battle during World War I. And no area of the globe was safe. Eskimos living in remote outposts in the frozen tundra were sickened and killed by the flu in such numbers that entire villages were wiped out. Scientists have recently rediscovered shards of the flu virus frozen in Alaska and preserved in scraps of tissue in a government warehouse. Gina Kolata, an acclaimed reporter for The New York Times, unravels the mystery of this lethal virus with the high drama of a great adventure story. Delving into the history of the flu and previous epidemics, detailing the science and the latest understanding of this mortal disease, Kolata addresses the prospects for a great epidemic recurring, and, most important, what can be done to prevent it.

The Deadly Truth

The Deadly Truth
Author: Gerald N. Grob
Publisher: Harvard University Press
Total Pages: 374
Release: 2009-07
Genre: History
ISBN: 9780674037946

The Deadly Truth chronicles the complex interactions between disease and the peoples of America from the pre-Columbian world to the present. Grob's ultimate lesson is stark but valuable: there can be no final victory over disease. The world in which we live undergoes constant change, which in turn creates novel risks to human health and life. We conquer particular diseases, but others always arise in their stead. In a powerful challenge to our tendency to see disease as unnatural and its virtual elimination as a real possibility, Grob asserts the undeniable biological persistence of disease. Diseases ranging from malaria to cancer have shaped the social landscape--sometimes through brief, furious outbreaks, and at other times through gradual occurrence, control, and recurrence. Grob integrates statistical data with particular peoples and places while giving us the larger patterns of the ebb and flow of disease over centuries. Throughout, we see how much of our history, culture, and nation-building was determined--in ways we often don't realize--by the environment and the diseases it fostered. The way in which we live has shaped, and will continue to shape, the diseases from which we get sick and die. By accepting the presence of disease and understanding the way in which it has physically interacted with people and places in past eras, Grob illuminates the extraordinarily complex forces that shape our morbidity and mortality patterns and provides a realistic appreciation of the individual, social, environmental, and biological determinants of human health.

The Transmission of Epidemic Influenza

The Transmission of Epidemic Influenza
Author: R.E. Hope-Simpson
Publisher: Springer Science & Business Media
Total Pages: 257
Release: 2013-11-11
Genre: Medical
ISBN: 1489923853

THE PLAGUE YEARS Mankind has always been fascinated by "origins," and biologists are no exception. Darwin is our most famous example. What is the origin of mankind, of species, of infectious diseases? In the last few years we have seen the emergence and spread of some apparently "new" viruses, such as HIV -1 and the virus causing bovine spongiform encephalomyelopathy. But are these, in fact, entirely new agents, or mutated forms of "old" viruses that have evolved along with us for eons? Edgar Hope-Simpson could not have written this book at a more opportune moment. He is a firm believer in gradual evolution, rather than the sudden arrival of new agents. I suspect that he would also have a naturalist's Darwinian approach for the origin of AIDS. It has been a source of some amazement to me over the years how even the most innovative scientists conform to a current hypothesis. Pioneer thinking comes more easily to persons outside the scientific mainstream. Edgar Hope Simpson has always struck me as a modem-day naturalist of the classic style, observant and perhaps a little maverick in line of thought. Certainly, the central hypothesis propounded in this book will be controversial to many scientists. From his unique citadel, the Epidemiological Research Unit in Cirencester, he has carefully reexamined mortality data from old records as well as new.