This handbook brings together an international group of experts to offer a comprehensive resource on occupational stress. Including both theoretical and practical perspectives, it examines ways to reduce and treat stress, as well as the physiological, psychosocial, and neural underpinnings of it. Through 24 original and carefully selected essays, the authors offer new insights, resources, and tools to better understand, manage and treat stress in a professional environment. The book’s chapters are divided into 5 parts that address the conceptualisation of stress; present theoretical models (including the contribution of animal models); examine the psychological and physiological aspects of stress and ways to assess it; delve into psychosocial risks at work and their assessment (means and methods); and investigate how to cope with stress at work, including resilience training. Aspects such as the effects of leadership, simulation training, and stress-tests for hiring are also presented and discussed. The volume ends by exploring broader considerations regarding stress and culture, stress and occupational sectors (with a chapter focusing on studentship), and the pharmacology of stress. This handbook is an essential reference for researchers in organisational psychology, as well as business and management and education, who are interested in stress. Healthcare workers and therapists who treat stress will also find an invaluable resource in this far-reaching yet accessible collection.